SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
for Cancer, Metastatic
67 locations incl. Birmingham
Sponsor: Massive Bio, Inc.
Sex: All·Age: All ages
Code: NCT03452774·Recruiting
Non-Hodgkin lymphoma Clinical Trials in Silver Spring, MD
As of June 2026, 1 paid clinical trial is recruiting for Non-Hodgkin lymphoma in Silver Spring, Maryland. Lymphoma research explores bispecific antibodies, CAR-T cell therapies, and new targeted agents for Hodgkin and non-Hodgkin lymphomas. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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1 clinical trial for Non-Hodgkin lymphoma
·Clear filters·↓ Download CSVAbout research studies in Silver Spring
Silver Spring has approximately 69 recruiting research studies across a wide range of therapeutic areas. Maryland hosts Johns Hopkins Medicine and the NIH Clinical Center in Bethesda, giving participants access to some of the most advanced early-phase research in the country.
Top Research Study Locations in Silver Spring
Researchers run research studies in Silver Spring, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Holy Cross Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Carcinoma, Ovarian Epithelial, Elevated CA15-3 or CEA or CA27-29 | 13 |
| Maryland Oncology Hematology, P.A. | Carcinoma, Non-Small-Cell Lung, Gastroesophageal Junction Cancer, Advanced Non-Small Cell Lung Cancer | 6 |
| Adventist Healthcare White Oak Medical Center | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, Acute Myocardial Infarction | 3 |
| Jadestone Clinical Research, LLC | Acute Myocardial Infarction (AMI), Cardiovascular Risk, Influenza | 3 |
| Maryland Oncology Hematology | Cancer, Chronic Lymphocytic Leukemia (CLL), Metastatic Prostate Cancer | 3 |
| Maryland Oncology Hematology - Silver Spring | Untreated, Unresectable, or Metastatic Colorectal Cancer, Chronic Lymphocytic Leukemia, Multiple Myeloma | 3 |
| Food and Drug Administration | Age-Related Macular Degeneration, Cone Dystrophy, Cone Rod Dystrophy | 2 |
| Jadestone Clinical Research | COVID-19 Infection, COVID-19 SARS-CoV-2 Infection | 2 |
| Javara | Focal Epilepsy | 2 |
| Maryland Oncology Hematology P A | Carcinoma, Non-Small-Cell Lung, Early Breast Cancer | 2 |
| TSC Alliance | Adult Caregivers of Individuals With TSC, Lymphangioleiomyomatosis, Tuberous Sclerosis | 2 |
| Holy Cross Hospital - Silver Spring | Breast Cancer, Folate Receptor-Alpha Positive, Recurrent Ovarian Cancer | 2 |
| Children's National Medical Center, Children's Research Institute | Caregiver Burden, Tracheostomy | 1 |
| Childrens National Hospital | Palliative Care Education | 1 |
| Direct Biologics Investigational Site | ARDS, Acute Respiratory Distress Syndrome | 1 |
| Food and Drug Administration (FDA) | Glaucoma | 1 |
| Javara - Privia Medical Group - Silver Spring Lockwood | Asthma | 1 |
| Javara Inc./Privia Medical Group - Silver Spring, MD - Columbia Pike | Proteinuric Kidney Disease | 1 |
| Maryland Oncology Hematology P.A. | Breast Cancer | 1 |
| Maryland Oncology Hematology, PA | Breast Cancer | 1 |
| Massive Bio SYNERGY-AI site | BRCA Gene Rearrangement, Bladder Cancer, Breast Cancer | 1 |
| Medical Center Orthotics & Prosthetics | Lower Extremity, Pareses | 1 |
| Medical Center Orthotics and Prosthetics - Silver Spring | Upper Limb Amputation Above Elbow, Upper Limb Amputation Below Elbow | 1 |
| Privia Medical Group, LLC - Kelly's Collaborative Care - Javara - PPDS | Type II Diabetes Mellitus | 1 |
| Sleep Research Center (SRC), Walter Reed Army Institute of Research | Acute Stress Reaction, Fear of Spiders | 1 |
Active & Upcoming Studies in Silver Spring (2026)
Recruiting trials in Silver Spring grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (35 active studies)
- A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer · Phase 2, Phase 3 · Pfizer
- Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer · Phase 3 · Pfizer
Vaccines (4 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
Neurology & pain (3 active studies)
- Long-term Safety and Tolerability of BHV-7000 · Phase 2 · Biohaven Therapeutics Ltd.
- A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy · Phase 2, Phase 3 · Biohaven Therapeutics Ltd.
Cardiovascular (3 active studies)
Eye & vision (3 active studies)
- Retinal Blood Flow and Autoregulation · Phase 4 · University of Maryland, Baltimore
- Adaptive Optics Imaging of Outer Retinal Diseases · Food and Drug Administration (FDA)
Diabetes & metabolic (1 active study)
- A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus · Phase 2 · Corxel Pharmaceuticals
Common conditions studied in Silver Spring
- Breast Cancer (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Endometrial Cancer (4 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Carcinoma, Non-Small-Cell Lung (3 active studies). Recruiting Carcinoma, Non-Small-Cell Lung studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Asthma (2 active studies). Asthma research tests biologic therapies targeting IL-4, IL-5, and TSLP pathways for moderate-to-severe and eosinophilic disease.
- Cancer (2 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Fallopian Tube Cancer (2 active studies). Recruiting Fallopian Tube Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Silver Spring
- AstraZeneca
- Pfizer
- AbbVie
- Merck Sharp & Dohme LLC
- Biohaven Therapeutics Ltd.
Local regulations and guidelines
Clinical trials in Maryland are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Maryland research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Silver Spring. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Silver Spring
Hipa.ai aggregates every recruiting study in Silver Spring from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Silver Spring?
There are approximately 69 recruiting clinical trials in Silver Spring, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Silver Spring pay participants?
Most recruiting trials in Silver Spring compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Silver Spring?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Silver Spring?
The most common conditions under active study in Silver Spring include Breast Cancer (4), Endometrial Cancer (4), Carcinoma, Non-Small-Cell Lung (3), Asthma (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Silver Spring?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Silver Spring on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Silver Spring?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Silver Spring?
Recruiting research sites in Silver Spring include Holy Cross Hospital, Maryland Oncology Hematology, P.A., Adventist Healthcare White Oak Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Silver Spring right now?
The largest active categories in Silver Spring are Cancer & tumors (35), Vaccines (4), Neurology & pain (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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