ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
for Bladder Carcinoma
Sites in Toledo, Cleveland +25 more locations
Sponsor: Guardant Health, Inc.
Sex: All·Age: 18+
Code: NCT05059444·Recruiting·Listed Sep 2021
Lung oncology Clinical Trials in Toledo, OH
As of July 2026, 4 paid clinical trials are recruiting for Lung oncology in Toledo, Ohio. Lung oncology trials investigate EGFR, ALK, KRAS, and other driver-mutation targeted therapies alongside immunotherapy combinations for non-small cell, small cell, and mesothelioma studies. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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4 clinical trials for Lung oncology
·Clear filters·↓ Download CSVClinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
for Pulmonary Nodule, Solitary
Sites in Toledo, Cincinnati +20 more locations
Sponsor: Veracyte, Inc.
Sex: All·Age: 29 - 85
Code: NCT06426628·Recruiting·Listed May 2024
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
Sites in Toledo, Sylvania +638 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
for Non-Small Cell Lung Cancer
Drug: Rilvegostomig
Sites in Toledo, Maumee +47 more locations
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT06357533·Phase 3·Recruiting·Listed Apr 2024
About research studies in Toledo
Toledo has approximately 121 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Top Research Study Locations in Toledo
Researchers run research studies in Toledo, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Ganglioneuroblastoma, Nodular | 31 |
| Mercy Health - Saint Anne Hospital | Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer | 20 |
| ProMedica Toledo Hospital | Acute Ischemic Stroke, Heart Failure, Stroke | 15 |
| Mercy Health - Saint Vincent Hospital | Malignant Solid Neoplasm, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 10 |
| Mercy Health Sylvania Radiation Oncology Center | Malignant Solid Neoplasm, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 8 |
| Mercy Health - St. Vincent Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 5 |
| Mercy Health St. Vincent Medical Center | Acute Ischemic Stroke, Chronic Subdural Hematoma, Heart Failure | 5 |
| Toledo Clinic Cancer Center | Bladder Carcinoma, Colorectal Cancer, Cutaneous Melanoma | 4 |
| ProMedica | Acute Myocardial Infarction (AMI), Cardiovascular Risk, Ischemic Stroke | 4 |
| University of Toledo Medical Center | Atrial Fibrillation (AF), Parkinsons Disease (PD), Sjögren's Syndrome | 3 |
| ADARx Clinical Site | HAE, Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2 | 2 |
| Mercy St. Vincent Medical Center | Intracranial Atherosclerotic Stenosis (ICAS), Stroke, Viral Pneumonia | 2 |
| Saint Vincent Mercy Medical Center | Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | 2 |
| Toledo Children's Hospital | Cystic Fibrosis, Cystic Fibrosis (CF), Cystic Fibrosis Pulmonary Exacerbation | 2 |
| Toledo Institute of Clinical Research Inc. | Asthma, Moderate to Severe Chronic Obstructive Pulmonary Disease | 2 |
| US Renal Care - Alexis | Hyperphosphatemia, Chronic Kidney Disease Requiring Chronic Dialysis, Chronic Kidney Disease, Receiving Dialysis | 2 |
| Asthma & Allergy Center - Toledo | Asthma, Chronic Obstructive Pulmonary Disease | 2 |
| Corxel Investigational Site | Acute Ischemic Stroke | 1 |
| Deca Health | Lumbar Spinal Stenosis | 1 |
| Interventional Pain Consultants | Chronic Pain | 1 |
| Jobst Vascular Institute - ProMedica Hospital | Pulmonary Embolism | 1 |
| Kymera Investigative Site | Eosinophilic Asthma | 1 |
| Mercy Health | Aneurysm, Brain, Stroke, Thromboses, Intracranial | 1 |
| Mercy Health Neuroscience Institute | Vertebral Artery Stenosis | 1 |
| Mercy Health St.Vincent Medical Center LLC | Interstitial Lung Disease, Progressive Pulmonary Fibrosis | 1 |
Active & Upcoming Studies in Toledo (2026)
Recruiting trials in Toledo grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (46 active studies)
- Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia · Phase 3 · Children's Oncology Group
- Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer · Phase 3 · NRG Oncology
Neurology & pain (14 active studies)
- Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis · Phase 3 · ProMedica Health System
- Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial · Phase 2, Phase 3 · ProMedica Health System
Cardiovascular (10 active studies)
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program · Phase 3 · Alliance for Clinical Trials in Oncology
Common conditions studied in Toledo
- Asthma (7 active studies). Asthma research tests biologic therapies targeting IL-4, IL-5, and TSLP pathways for moderate-to-severe and eosinophilic disease.
- Heart Failure (5 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Stroke (5 active studies). Stroke trials test acute reperfusion strategies, neuroprotective agents, and rehabilitation technologies to improve recovery.
- ARDS (4 active studies). Recruiting ARDS studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- ARDS (Acute Respiratory Distress Syndrome) (4 active studies). Recruiting ARDS (Acute Respiratory Distress Syndrome) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Ischemic Stroke (4 active studies). Stroke trials test acute reperfusion strategies, neuroprotective agents, and rehabilitation technologies to improve recovery.
Leading research sponsors in Toledo
- Children's Oncology Group
- National Cancer Institute (NCI)
- NRG Oncology
- Alliance for Clinical Trials in Oncology
- SWOG Cancer Research Network
Local regulations and guidelines
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Toledo. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Toledo
Hipa.ai aggregates every recruiting study in Toledo from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Toledo?
There are approximately 121 recruiting clinical trials in Toledo, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Toledo pay participants?
Most recruiting trials in Toledo compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Toledo?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Toledo?
The most common conditions under active study in Toledo include Asthma (7), Heart Failure (5), Stroke (5), ARDS (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Toledo?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Toledo on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Toledo?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Toledo?
Recruiting research sites in Toledo include ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Mercy Health - Saint Anne Hospital, ProMedica Toledo Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Toledo right now?
The largest active categories in Toledo are Cancer & tumors (46), Neurology & pain (14), Cardiovascular (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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