Paid Clinical Trials in Toledo, OH
As of June 2026, 158 paid clinical trials are recruiting in Toledo, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Toledo offers studies at sites including Mercy Health - Saint Anne Hospital for conditions such as Asthma, Heart Failure, ARDS, ARDS (Acute Respiratory Distress Syndrome). Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Toledo
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Toledo has approximately 158 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Top Research Study Locations in Toledo
Researchers run research studies in Toledo, OH at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mercy Health - Saint Anne Hospital | Stage IV Lung Cancer AJCC v8, Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8 | 32 |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Ganglioneuroblastoma, Nodular | 30 |
| Mercy Health - Saint Vincent Hospital | Malignant Solid Neoplasm, Chronic Lymphocytic Leukemia, Melanoma | 19 |
| ProMedica Toledo Hospital | Acute Ischemic Stroke, Heart Failure, Acute Disease | 15 |
| Toledo Clinic Cancer Centers-Toledo | Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 14 |
| Mercy Health Sylvania Radiation Oncology Center | Malignant Solid Neoplasm, Melanoma, RISS Stage I Plasma Cell Myeloma | 11 |
| Mercy Health - St. Vincent Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 6 |
| Toledo Clinic Cancer Center | Bladder Carcinoma, Cancer Harboring BRAF Alterations, Colorectal Cancer | 6 |
| University of Toledo Medical Center | Atrial Fibrillation (AF), Chronic Pain, Pain | 6 |
| Mercy Health St. Vincent Medical Center | Acute Ischemic Stroke, Chronic Subdural Hematoma, Heart Failure | 5 |
| University of Toledo | Acute Myocardial Infarction (AMI), Cardiovascular Risk, Castration Levels of Testosterone | 5 |
| ProMedica | Acute Myocardial Infarction (AMI), Cardiovascular Risk, Ischemic Stroke | 4 |
| Toledo Institute of Clinical Research | C. Diff Infection, C.Difficile Diarrhea, CDI | 3 |
| Asthma & Allergy Center - Toledo | Asthma, Chronic Obstructive Pulmonary Disease | 3 |
| ADARx Clinical Site | HAE, Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2 | 2 |
| Saint Vincent Mercy Medical Center | Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | 2 |
| Toledo Children's Hospital | Cystic Fibrosis, Cystic Fibrosis (CF), Cystic Fibrosis Pulmonary Exacerbation | 2 |
| Toledo Institute of Clinical Research Inc. | Asthma, Moderate to Severe Chronic Obstructive Pulmonary Disease | 2 |
| Clinical Trial Site | Advanced Breast Cancer, Breast Cancer, ER Positive Breast Cancer | 1 |
| Consulting Orthopaedic Associates | Spinal Stenosis Lumbar | 1 |
| Corxel Investigational Site | Acute Ischemic Stroke | 1 |
| Deca Health | Lumbar Spinal Stenosis | 1 |
| Franklin Avenue Primary Care Center | Suicidal Ideation, Suicide Prevention, Suicide, Attempted | 1 |
| Hospital Council of Northwest Ohio | Advance Care Planning, Advance Directives, Chronic Illness | 1 |
| Interventional Pain Consultants | Chronic Pain | 1 |
| Kymera Investigative Site | Eosinophilic Asthma | 1 |
| Local Institution - 0013 | Multiple Myeloma | 1 |
| Local Institution - 2119 | Locally Advanced Solid Tumors, Metastatic Solid Tumors | 1 |
| Mercy Health | Aneurysm, Brain, Stroke, Thromboses, Intracranial | 1 |
| Mercy Health - St. Anne Cancer Center | Patients With Non-Small Cell Lung Cancer | 1 |
| Mercy Health Neuroscience Institute | Vertebral Artery Stenosis | 1 |
| Mercy Health St.Vincent Medical Center LLC | Interstitial Lung Disease, Progressive Pulmonary Fibrosis | 1 |
| Mercy Health- St. Vincent Medical Center LLC | Diastolic Heart Failure, Heart Failure, Heart Failure With Mid Range Ejection Fraction | 1 |
| Mercy Saint Vincent Medical Center | Cannabinoid Hyperemesis Syndrome | 1 |
| Mercy St. Vincent Medical Center | Viral Pneumonia | 1 |
| NGM Clinical Study Site | CRC (Colorectal Cancer), Cancer Cachexia, Colorectal Cancer | 1 |
| Northwest Ohio Hemophilia Treatment Center at the Toledo Hospital | Bleeding Disorder, Connective Tissue Disorder, Factor IX Deficiency | 1 |
| Octapharma Research Site | Acute Hereditary Angio Edema | 1 |
| ProMedica Physicians Pulmonary and Sleep Medicine - Toledo | Bronchiectasis | 1 |
| ProMedica Toledo | Longstanding Persistent Atrial Fibrillation, Persistent Atrial Fibrillation | 1 |
| St. Anne Hospital | Lumbar Spinal Stenosis | 1 |
| TG Therapeutics Investigational Trial Site | Multiple Sclerosis, Relapsing Multiple Sclerosis | 1 |
| Taylor Cancer Research Foundation | Extensive Stage Small Cell Lung Cancer (ES-SCLC) | 1 |
| Teva Investigational | Asthma | 1 |
| The Toledo Clinic Cancer Center | Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations | 1 |
| The University of Toledo | Cancer | 1 |
| The University of Toledo Medical Center | Lumbar Spinal Stenosis | 1 |
| Toledo | Heart Failure With Preserved Ejection Fraction, Pulmonary Hypertension | 1 |
| Toledo Clinic | Chronic Pain | 1 |
| Toledo Clinic Cancer Center - Toledo | Limited-stage Small Cell Lung Cancer (LS-SCLC) | 1 |
Active & Upcoming Studies in Toledo (2026)
Recruiting trials in Toledo grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (69 active studies)
- Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer · Phase 3 · NRG Oncology
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Neurology & pain (13 active studies)
- Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis · Phase 3 · ProMedica Health System
- Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial · Phase 2, Phase 3 · ProMedica Health System
Cardiovascular (12 active studies)
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program · Phase 3 · Alliance for Clinical Trials in Oncology
Common conditions studied in Toledo
- Asthma (8 active studies). Asthma research tests biologic therapies targeting IL-4, IL-5, and TSLP pathways for moderate-to-severe and eosinophilic disease.
- Heart Failure (6 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- ARDS (4 active studies). Recruiting ARDS studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- ARDS (Acute Respiratory Distress Syndrome) (4 active studies). Recruiting ARDS (Acute Respiratory Distress Syndrome) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Ischemic Stroke (4 active studies). Stroke trials test acute reperfusion strategies, neuroprotective agents, and rehabilitation technologies to improve recovery.
- Acute Respiratory Distress Syndrome (4 active studies). Recruiting Acute Respiratory Distress Syndrome studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Toledo
- National Cancer Institute (NCI)
- Children's Oncology Group
- NRG Oncology
- SWOG Cancer Research Network
- AstraZeneca
Local regulations and guidelines
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Toledo. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Toledo
Hipa.ai aggregates every recruiting study in Toledo from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Toledo?
There are approximately 158 recruiting clinical trials in Toledo, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Toledo pay participants?
Most recruiting trials in Toledo compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Toledo?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Toledo?
The most common conditions under active study in Toledo include Asthma (8), Heart Failure (6), ARDS (4), ARDS (Acute Respiratory Distress Syndrome) (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Toledo?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Toledo on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Toledo?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Toledo?
Recruiting research sites in Toledo include Mercy Health - Saint Anne Hospital, ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Mercy Health - Saint Vincent Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Toledo right now?
The largest active categories in Toledo are Cancer & tumors (69), Neurology & pain (13), Cardiovascular (12). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.