As of August 2026, 157 paid clinical trials are recruiting in Tyler, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Tyler offers studies at sites including Texas Oncology - Northeast Texas for conditions such as Crohn's Disease, Ulcerative Colitis, Multiple Myeloma, Endometrial Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Tyler, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Texas Oncology - Northeast Texas | Carcinoma, Non-Small-Cell Lung, Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung (NSCLC) | 23 |
| Tyler Research Institute, LLC | Crohn's Disease, Ulcerative Colitis, Colitis, Ulcerative | 14 |
| Tyler Research Institute | Ulcerative Colitis, Obesity or Overweight, Crohn's Disease | 8 |
| CHRISTUS Trinity Mother Frances Health System | Atrial Fibrillation, Beta-blocker Therapy, Cardiomyopathy | 7 |
| Texas Oncology - Northeast | Advanced Lung Cancer, Advanced Solid Tumor, Carcinoma, Non-Small-Cell Lung | 5 |
| Texas Oncology - Tyler | Breast Cancer, Bone Metastases From Solid Tumors, Cancer | 5 |
| Texas Oncology | Advanced/Metastatic Solid Tumors, Colorectal Cancer, Esophageal Cancer | 4 |
| Texas Oncology, P.A. - Tyler | Gastric Cancer, Gastroesophageal Junction Cancer, Metastatic Castration-resistant Prostate Cancer | 4 |
| The University of Texas Health Science Center at Tyler | Carcinoma, Non-Small-Cell Lung, Crohn Disease, Extensive Stage Small Cell Lung Cancer (ES-SCLC) | 4 |
| Tyler Retina Consultants | DME, Diabetic Macular Edema, Diabetic Macular Edema (DME) | 4 |
| The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center | Non-small Cell Lung Cancer, Triple-Negative Breast Cancer, Breast Neoplasms | 4 |
| Texas Oncology Tyler | Chronic Lymphocytic Leukemia, CLL, Small Lymphocytic Lymphoma | 3 |
| Texas Oncology-Northeast Texas | Breast Cancer, Breast Neoplasms, Non-Small Cell Lung Cancer Metastatic | 3 |
| University of Texas Health Center at Tyler | KRAS G12C Lung Cancer, Moderately to Severely Active Crohns Disease, Moderately to Severely Active Ulcerative Colitis | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC), Non-Small Cell Lung Cancer | 2 |
| GSK Investigational Site | Multiple Myeloma, Neoplasms, Newly Diagnosed Multiple Myeloma | 2 |
| Precision Spine Care | Degenerative Disc Disease, Degenerative Disc Disease (DDD), Disc Degeneration | 2 |
| Texas Oncology Northeast Texas | Extensive Stage Small-cell Lung Cancer, Metastatic Castration-resistant Prostate Cancer, Small-cell Lung Cancer | 2 |
| Texas Oncology- Northeast Texas | B-Cell Non-Hodgkins Lymphoma, Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC) | 2 |
| Texas Oncology-Tyler | Essential Thrombocythemia, Ovarian Cancer | 2 |
| Tyler Cardiovascular Consultants | Atrial Fibrillation (AF), Cardiovascular Disease | 2 |
| UT Health East Texas HOPE Cancer Center | Carcinoma, Non-Small Cell Lung, Colorectal Neoplasms, Cutaneous Squamous Cell Cancer | 2 |
| 016 | Advanced Solid Tumor | 1 |
| Adverum Clinical | Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD | 1 |
Recruiting trials in Tyler grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 157 recruiting clinical trials in Tyler, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Tyler compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Tyler include Crohn's Disease (11), Ulcerative Colitis (8), Multiple Myeloma (6), Endometrial Cancer (5), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Tyler on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Tyler include Texas Oncology - Northeast Texas, Tyler Research Institute, LLC, Tyler Research Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Tyler are Cancer & tumors (77), Cardiovascular (15), Eye & vision (8). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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