Cataract Clinical Trials

Recruiting cataract studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat cataract. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting cataract studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting cataract trials

Within

Clinical Evaluation of a Novel Trifocal IOL

for Aphakia

Sponsor: Alcon Research

Sex: All·Age: 22+

Code: NCT07587138

Clinical Trial on the Visual Function of Enhanced Monofocal and EDoF Intraocular Lenses

for Cataract

Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Sex: All·Age: 45 - 80

Code: NCT07715071

Clareon TruPlus vs Tecnis Eyhance IOLs in Cataract Patients

for Cataract

1 site in Gainesville

Sponsor: Gainesville Eye Associates

Sex: All·Age: 18+

Code: NCT07658040

Prospective, Randomized, Parallel-group Comparison of Two Refractive EDOF Intraocular Lenses: Johnson & Johnson Tecnis PureSee Versus 1stQ Comfort Z-EDOF

for Cataract

Sponsor: Vienna Hospital Association

Sex: All·Age: 40+

Code: NCT07688681

OCT-PRO Model vs. Clinicians: Cataract Surgery Outcome Prediction

for Cataract

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 18 - 90

Code: NCT07713069

Influence of Cataract Surgery on Corneal Biomechanical Properties in Patients With Pseudoexfoliation Syndrome

for Pseudoexfoliation Syndrome

Sponsor: Kata Culina

Sex: All·Age: 50 - 85

Code: NCT07719101

Lacrifill for Ocular Surface Optimization in Cataract Surgery

for Cataract

1 site in Largo

Sponsor: The Eye Institute of West Florida

Sex: All·Age: 40+

Code: NCT07648095

Toric Performance And Constant Evaluation

for Cataract

Sponsor: Carl Zeiss Meditec AG

Sex: All·Age: 18+

Code: NCT07471295·Phase 4

Apply to this trial

Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing County

for Visual Impairment

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07694505

Effects of Oxygen Cage Support During Cataract Surgery

for Cataract

Sponsor: Ataturk University

Sex: All·Age: 18 - 90

Code: NCT07632326

Post-refractive IOL Outcomes With Clareon TruPlus

for Cataract

1 site in Greensboro

Sponsor: Laser Defined Vision

Sex: All·Age: 18+

Code: NCT07610226

Apply to this trial

Small RNA tRF-31 Changes in Patients With Age-Related Cataract

for Cataract

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Sex: All·Age: 18+

Code: NCT07672899

Apply to this trial

Strengthening Community- to- Hospital Eye Care Pathways From Boko Eye Care Center in Rural Assam

for Cataract

Sponsor: Seva Canada Society

Sex: All·Age: 18+

Code: NCT07333248

A Prospective, Randomized, Subject- and Examiner-Masked, Multicenter Study Comparing Bilateral Clareon TruPlus and Bilateral Clareon Monofocal Intraocular Lens Implantation (Spherical and Toric) in Cataract Subjects

for Cataract

1 site in Sugar Land

Sponsor: Berkeley Eye Center

Sex: All·Age: 22+

Code: NCT07693205·Phase 4

Apply to this trial

Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery

for Cataract

1 site in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: All ages

Code: NCT07715591

Apply to this trial

Visual and Patient Reported Outcomes With Clareon TruPlus

for Cataract

1 site in Saint Louis Park

Sponsor: OVO LASIK + Lens

Sex: All·Age: 18+

Code: NCT07648355

Apply to this trial

Community-Based Eye Screening With Structured Referral Tracking for Preventing Avoidable Blindness in Adults in Rawalpindi, Pakistan

for Cataract

Sponsor: Health Services Academy, Islamabad, Pakistan

Sex: All·Age: 18+

Code: NCT07611682

Binocular and Monocular Distance-Corrected Visual Performance and Defocus Characteristics of Clareon Truplus Intraocular Lens (IOL)

for Cataract

1 site in Encino

Sponsor: Colvard Kandavel Eye Center

Sex: All·Age: 50 - 80

Code: NCT07589894

Artificial Intelligence-assisted Diagnosis in Ophthalmology

for Macular Degeneration

Sponsor: Marisse Masis-Solano

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07497815

Evaluation of the Effectiveness of Three Tear Substitute Formulations in Postoperative Discomfort After Cataract Surgery

for Cataract

Sponsor: Democritus University of Thrace

Sex: All·Age: 45 - 85

Code: NCT07581548

Study on Eye-Brain Cross-Organ Mapping and Systemic Disease Association Based on Multimodal Big Data

for Cataract

Sponsor: Beijing Friendship Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07541651

A Study on the Application of Smart Bed-Exit Alert Assistive Devices for Detecting Preoperative Bed Exits in Ophthalmic Surgery Patients in the Operating Room

for Cataract

Sponsor: National Taiwan University Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07693829

Apply to this trial

Effect of Surgical Planning Prompts on Elective Surgery Acceptance Rate

for Cataract

Sponsor: Tongji University

Sex: All·Age: 18+

Code: NCT07544641

Rebamipide Versus Diquafosol for Perioperative Dry Eye in Cataract Surgery

for Dry Eye Disease (DED)

Sponsor: Samsung Medical Center

Sex: All·Age: 40+

Code: NCT07397949·Phase 4

Partial Range Of Field IOLs in DMEK-Enabled Procedures

for Cataract

Sponsor: Universitair Ziekenhuis Brussel

Sex: All·Age: 40 - 90

Code: NCT07441616

Comparison of Early Postoperative Visual Acuity Between Intracapsular and Supracapsular Phacoemulsification: A Randomized Controlled Clinical Trial

for Cataract

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 50 - 90

Code: NCT07407049

JASPER™ Robotic Surgical System (Formerly Known as the ORYOM™ Robotic Surgical System) in Cataract Surgery

for Cataract

Sponsor: ForSight Robotics Ltd

Sex: All·Age: 55 - 80

Code: NCT07468409

Apply to this trial

Surgical Procedure Efficiency Evaluation stuDy

for Cataract

Sponsor: Alcon Research

Sex: All·Age: 18+

Code: NCT07228091

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Evaluation of Visual Outcomes, Complications, and Neuroadaptation Following Bilateral Implantation of enVista Envy Trifocal Intraocular Lenses

for Cataract

Sponsor: Pomeranian Medical University Szczecin

Sex: All·Age: 50 - 75

Code: NCT07696130

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Clinical Outcomes of Sedation in Cataract Surgery Performed Under Topical Anesthesia

for Cataract

Sponsor: Istanbul University - Cerrahpasa

Sex: All·Age: 50+

Code: NCT07347886

Comparison of Visual Outcomes and Patient Satisfaction in Mild to Moderate Glaucoma Patients Undergoing Cataract Surgery With EDOF Versus Monofocal IOLs

for GLAUCOMA 1, OPEN ANGLE, D (Disorder)

Sponsor: OMIQ Research

Sex: All·Age: 18+

Code: NCT07436871

Aqueous Humor and Ocular Tissue Analysis in Glaucoma and Cataract

for Primary Open-Angle Glaucoma (POAG)

Sponsor: Military Institute od Medicine National Research Institute

Sex: All·Age: 18+

Code: NCT07462000

Apply to this trial

Vivinex Impress XY1-EM vs RayOne EMV

for Cataract

Sponsor: Medical University of Bialystok

Sex: All·Age: 21 - 80

Code: NCT06891092

Apply to this trial

Comparing Single Versus Multiple Anti-VEGF Injections in Diabetic Patients Undergoing Cataract Surgery

for Diabetic Retinopathy (DR)

Sponsor: Ahmad Zeeshan Jamil

Sex: All·Age: 40+

Code: NCT07301775·Phase 4

Effect of Dry Eye Treatment on Corneal Astigmatism Measurements

for Dry Eye

Sponsor: Jin Yang

Sex: All·Age: All ages

Code: NCT07657858

Apply to this trial

Xinxing Eye Cohort Study

for Refractive Errors

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 0 - 100·Accepts healthy volunteers

Code: NCT07257536

Visual Function of Enhanced Monofocal Intraocular Lenses

for Cataract

Sponsor: Vienna Institute for Research in Ocular Surgery

Sex: All·Age: 21 - 105

Code: NCT07262021

The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients

for Peripheral Vascular Access in Pediatric Patients

Sponsor: Sibel Seçkin Pehlivan

Sex: All·Age: 0 Days - 18 Days

Code: NCT07315711

Dexmedetomidine and Propofol for Sedation in Cataract Surgery.

for Sedation

Sponsor: Saint-Joseph University

Sex: All·Age: 18+

Code: NCT07556133

Apply to this trial

Intraocular Lens Calculation Using Artificial Intelligence

for Cataract

Sponsor: Johannes Kepler University of Linz

Sex: All·Age: 21+

Code: NCT07202767

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)

for Cataract

1 site in San Antonio

Sponsor: SpyGlass Pharma, Inc.

Sex: All·Age: 22+

Code: NCT07218796·Phase 3

Apply to this trial

Long-term Safety & Performance of REVISYON SDS100 in Mild to Moderate Cataract: Extension Study (EB-CE-02)

for Age-related Cataract

Sponsor: Edinburgh Biosciences Ltd

Sex: All·Age: 40+

Code: NCT07246915

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)

for Cataract

1 site in Houston

Sponsor: SpyGlass Pharma, Inc.

Sex: All·Age: 22+

Code: NCT07218783·Phase 3

Apply to this trial

Unity VCS: A Comparison Study Evaluating Corneal Clarity and Thickness

for Cataract

1 site in Matthews

Sponsor: Metrolina Eye Associates, PLLC

Sex: All·Age: 18+

Code: NCT07222150

Apply to this trial

Effective Phaco Time and Endothelial Cell Loss When Using Veritas

for Cataract

1 site in ‘Aiea

Sponsor: Aloha Vision Consultants

Sex: All·Age: All ages

Code: NCT07176416

Apply to this trial

Visual Outcomes of an Enhanced Monofocal Intraocular Lens Targeted for Monovision in Highly Myopic Eyes: a Randomized Controlled Trial

for Cataract

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 18 - 85

Code: NCT07168109

Comparative Clinical Study of Intraocular Lens Injectors Lioli™, Pioli™, and Pioli™ Plus

for Cataract

Sponsor: AST Products, Inc.

Sex: All·Age: 40+

Code: NCT07140029

Apply to this trial

To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value in Improving Postoperative Outcomes.

for Cataract

1 site in New York

Sponsor: The New York Eye & Ear Infirmary

Sex: All·Age: 18+

Code: NCT07425496

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Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract Patients

for Cataract

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 18+

Code: NCT07126470

Apply to this trial

Odyssey Evaluation in Post LASIK Patients

for Cataract

1 site in Venice

Sponsor: Center For Sight

Sex: All·Age: 50+

Code: NCT07260695·Phase 4

Apply to this trial

Binaural Sound During Phacoemulsification and Posterior Chamber Lens Implantation in Geriatric Patients

for Cataract

Sponsor: Seoul National University Hospital

Sex: All·Age: 65+

Code: NCT07609186

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Visual Outcomes in Patients Contralaterally Implanted With PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro

for Cataract

5 sites incl. Baltimore

Sponsor: Brian Shafer

Sex: All·Age: 18+

Code: NCT07076277

Multimedia Education to Reduce Anxiety and Improve Care Awareness in Cataract Surgery Patients

for Cataract

Sponsor: Chang Gung Memorial Hospital

Sex: All·Age: 18+

Code: NCT07030946

Apply to this trial

Performance of Large Language Models for Structured Recognition and Refractive Prediction

for Cataract

Sponsor: Jin Yang

Sex: All·Age: 18+

Code: NCT07183891

Apply to this trial

Research on a New Intelligent Mobile Screening and Diagnosis Pattern for Ocular Diseases

for Ophthalmic Diseases (Specific Types Not Restricted)

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT07003165

Capella Scientia Development Study

for Cataract

Sponsor: Alcon Research

Sex: All·Age: 18+

Code: NCT06987474

Apply to this trial

Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery

for Cataract

Sponsor: Suez Canal University

Sex: All·Age: 65+

Code: NCT07080229·Phase 3

Apply to this trial

Visual Performance of Clareon Vivity and PureSee IOL

for Cataract

Sponsor: OMIQ Research

Sex: All·Age: 50+

Code: NCT07165197

Apply to this trial

Research Based on IOLMaster700 Cataract Diagnosis and Classification System

for Cataract

Sponsor: Shanghai 10th People's Hospital

Sex: All·Age: 40+

Code: NCT07022444

Efficacy and Safety of Tran Cannula in Combined Pseudoexfoliative Glaucoma and Cataract Surgery Compared With Augmented Ocular Irrigation

for Glaucoma, Open Angle, Pseudo-exfoliative

Sponsor: Hôpital Privé de la Baie

Sex: All·Age: 18+

Code: NCT06979752

Apply to this trial

Cataract clinical trials — common questions

Are cataract clinical trials free to join?

Yes. Participating in a cataract clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a cataract clinical trial?

Each cataract study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a cataract trial near me?

Use the location controls above. We'll show recruiting cataract trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many cataract trials are recruiting right now?

We're currently tracking roughly 24 recruiting cataract trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Cataract trials by city

Bradenton, FL Encino, CA Fayetteville, AR Huntington Beach, CA Los Angeles, CA Portland, OR Salt Lake City, UT

Related specialties

Ophthalmology