Diabetic retinopathy Clinical Trials

Recruiting diabetic retinopathy studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat diabetic retinopathy. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting diabetic retinopathy studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting diabetic retinopathy trials

Within

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)

for Diabetic Retinopathy

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07705607·Phase 3

A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)

for Diabetic Retinopathy

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07705555·Phase 3

Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes

for Diabetic Retinopathy

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 22+

Code: NCT06763952

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498 Following Intravitreal Administration in Participants With Diabetic Retinopathy

for Diabetic Retinopathy

1 site in Glendale

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07588100·Phase 1

Apply to this trial

Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

for Diabetic Retinopathy

14 sites incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07592273·Phase 2, Phase 3

Apply to this trial

Community-Based Eye Screening With Structured Referral Tracking for Preventing Avoidable Blindness in Adults in Rawalpindi, Pakistan

for Cataract

Sponsor: Health Services Academy, Islamabad, Pakistan

Sex: All·Age: 18+

Code: NCT07611682

Strategies for Improving Linkage-to-Care After Eye Disease Screening

for Age Related Macular Degeneration

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 60+

Code: NCT06943599

Apply to this trial

Wide Field OCTA in Ocular Diseases

for Age - Related Macular Degeneration (AMD)

Sponsor: IRCCS San Raffaele

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07298174

High Resolution Imaging OCT Study

for Normal Eyes

Sponsor: Heidelberg Engineering GmbH

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07338461

Multicenter RCT of Eye-Brain Imaging in Diabetes Neurovascular Coupling

for Diabetes Mellitus

Sponsor: Hejiang Ye

Sex: All·Age: 18 - 70

Code: NCT06813274·Phase 2

A Preliminary Exploratory Clinical Trial to Evaluate the Efficacy of NPDR-01 Eye Drops in the Treatment of Non-Proliferative Diabetic Retinopathy

for Non-proliferative Diabetic Retinopathy (NPDR)

Sponsor: Sichuan Academy of Medical Sciences

Sex: All·Age: 35 - 75

Code: NCT07198815·EARLY_Phase 1

Longitudinal Observational Study of Diabetic Retinopathy Progression in Type 2 Diabetes Patients

for Diabetic Retinopathy

Sponsor: Association for Innovation and Biomedical Research on Light and Image

Sex: All·Age: 35 - 80

Code: NCT07458516

Apply to this trial

Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium

for Retinopathy

1 site in Ann Arbor

Sponsor: MediBeacon

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04008121·EARLY_Phase 1

Apply to this trial

Analysis of DR Progression to Identify Risks and Need for Treatment

for Diabetic Retinopathy

Sponsor: Association for Innovation and Biomedical Research on Light and Image

Sex: All·Age: 35 - 90

Code: NCT07417410

Apply to this trial

Investigating the Retardation Effect of OCTA-Guided Targeted Photocoagulation on the Progression of Non-Perfusion Areas in Diabetic Retinopathy Patients

for Diabetic Retinopathy

Sponsor: Sichuan Provincial People's Hospital

Sex: All·Age: 18+

Code: NCT06821633

Performance of the Electroretinogram, Performed and Interpreted by an Advanced Practice Nurse, in the Screening for Diabetic Retinopathy.

for Diabetic Retinopathy

Sponsor: CHU de Reims

Sex: All·Age: 18+

Code: NCT06782997

Apply to this trial

Retinal Investigation Using Optos OCT Device

for AMD - Age-Related Macular Degeneration

Sponsor: Optos, PLC

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06846151

An Interpretable Fundus Diseases Report Generating System Based On Weakly Labelings

for Retinal Diseases

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06918028

Video-based Patient Education Intervention for Diabetic Eye Screening in Latinx Communities

for Diabetic Retinopathy

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06257082

Apply to this trial

Effect of Video Viewing on Intravitreal Injection Experience

for Age Related Macular Degeneration

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Sex: All·Age: 18+

Code: NCT07002372

Apply to this trial

Remote Ischemic Conditioning for Non-Proliferative Diabetic Retinopathy

for Diabetic Retinopathy

Sponsor: Xuxiang Zhang, MD

Sex: All·Age: 40 - 80

Code: NCT06713720

Apply to this trial

AI-Powered DIY Screening System for Diabetic Retinopathy

for Diabetic Retinopathy

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06892353

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01

for Diabetic Retinopathy

8 sites incl. Beverly Hills

Sponsor: Vantage Biosciences Ltd

Sex: All·Age: 18+

Code: NCT06770933·Phase 2

Apply to this trial

Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus

for Diabetes

Sponsor: Yufan Wang

Sex: All·Age: 20 - 79

Code: NCT06821399

Apply to this trial

Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy

for Proliferative Diabetic Retinopathy

Sponsor: Vastra Gotaland Region

Sex: All·Age: 18+

Code: NCT06549023

Apply to this trial

Prospective Cohort Study on Predicting the Progression of Diabetic Microangiopathy Using Multimodal Eye Imaging

for Diabetic Retinopathy

Sponsor: Peking University Third Hospital

Sex: All·Age: 40 - 80

Code: NCT06727955

Pivotal Trial of Automated Artificial Intelligence (AI) Based System for Early Diagnosis of Diabetic Retinopathy

for Diabetes

1 site in Richmond Hill

Sponsor: iHealthScreen Inc

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07151001

Apply to this trial

Defining Retinal Structures Using Hyperspectral Retinal Imaging

for Age-Related Macular Degeneration

Sponsor: Center for Eye Research Australia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07555574

Apply to this trial

A Study Intravitreal THN391 in Diabetic Macular Oedema Secondary to Non-Proliferative Diabetic Retinopathy.

for Diabetic Macular Edema

Sponsor: Therini Bio Pty Ltd

Sex: All·Age: 18 - 80

Code: NCT06701721·Phase 1

Apply to this trial

Is Community Based Monitoring of Diabetic Maculopathy and Pre-proliferative Diabetic Retinopathy Safe?

for Diabetes Mellitus

Sponsor: Hywel Dda Health Board

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06955611

Apply to this trial

Evaluating a New Peptide Therapy for Retinal Diseases: AMD, Diabetic Retinopathy, and Dystrophies

for Retinitis Pigmentosa (RP)

Sponsor: Ace Cells Lab Limited

Sex: All·Age: All ages

Code: NCT06787482·Phase 1, Phase 2

Apply to this trial

Assessing of Artificial Intelligence-based Software Platform for Diabetic Retinopathy Screening

for Diabetic Retinopathy

Sponsor: The Filatov Institute of Eye Diseases and Tissue Therapy

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06879834

Apply to this trial

Clinical Trial of Keluoxin Capsules in the Treatment of Diabetic Kidney Disease with Diabetic Retinopathy

for Diabetic Kidney Disease

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 18 - 75

Code: NCT06660940·Phase 4

Glaucoma Algorithm Validation Study in African Population - the MAGIC Study

for Glaucoma

Sponsor: Centro Hospitalar Universitário Lisboa Norte

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06552247

Artificial Intelligence for Diagnosing Diabetic Retinopathy in Primary Care

for Diabetic Retinopathy

Sponsor: Hospital de Clinicas de Porto Alegre

Sex: All·Age: 18+

Code: NCT07236879

Apply to this trial

Single-Cell Insights Into Diabetic Retinopathy Mechanisms

for Diabetic Retinopathy

Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Sex: All·Age: 18+

Code: NCT06497608

Pre-operative Vabysmo in Patients With Non-clearing Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy

for Diabetic Retinopathy

1 site in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT06191094·Phase 4

Comparing Artificial Intelligence for Assisted Diagnosis of Diabetic Retinopathy

for Diabetic Retinopathy

Sponsor: Zhejiang University

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06423274

Exploring the Interaction Between Metabolic Disorders and NLPR3 Inflammasome Activation in DR Inflammatory Damage

for Diabetic Retinopathy

Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

Sex: All·Age: 40 - 90

Code: NCT06272565

Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

for Vision Impairment and Blindness

Sponsor: University of Copenhagen

Sex: All·Age: 70+·Accepts healthy volunteers

Code: NCT07015034

Apply to this trial

A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema

for Diabetic Macular Edema

Sponsor: Incepta Pharmaceuticals Ltd

Sex: All·Age: 18+

Code: NCT06305416·Phase 3

Apply to this trial

Community Screening Study of Diabetic Retinopathy in Tianjin in 2024

for Diabetic Retinopathy

Sponsor: Li Xiaorong

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06478407

Apply to this trial

Early Percutaneous Transluminal Angioplasty in Diabetic Foot Syndrome (PTA-DFS)

for Diabetic Foot

Sponsor: Heinrich-Heine University, Duesseldorf

Sex: All·Age: 18+

Code: NCT06124586

Apply to this trial

Early Retinal Neurodegeneration As Risk Factor, Biomarker and Pharmacological Target of Diabetic Retinopathy

for Diabetic Retinopathy

Sponsor: IRCCS Ospedale San Raffaele

Sex: All·Age: 40 - 80·Accepts healthy volunteers

Code: NCT06582472

Apply to this trial

I-TRUST: Implementation of Teleophthalmology in Rural Health Systems Study

for Diabetic Retinopathy

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT05254535

Exploring the Effectiveness of AI Generative Models for Diabetic Patients

for Diabetes Mellitus, Type 2

Sponsor: Pakistan Council of Scientific and Industrial Research

Sex: All·Age: 18 - 100

Code: NCT05883072

Apply to this trial

Retinal Care Data Repository

for Diabetic Retinopathy

Sponsor: Retinal Care Inc.

Sex: All·Age: 0 - 100

Code: NCT04794907

Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland

for Diabetes Mellitus, Type 2

Sponsor: Steno Diabetes Center Greenland

Sex: All·Age: 18+

Code: NCT06264427

Apply to this trial

Treating Early Stage Diabetic Retinopathy

for Diabetic Retinopathy

1 site in Decatur

Sponsor: VA Office of Research and Development

Sex: All·Age: 30 - 80

Code: NCT05132660·EARLY_Phase 1

Project Open - Use of Administrative Health Data to Increase Diabetic Retinopathy Screening

for Diabetes

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05074342

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for NAION

for Eye Diseases

Sponsor: The Foundation for Orthopaedics and Regenerative Medicine

Sex: All·Age: All ages

Code: NCT05147701·Phase 1

Apply to this trial

Biomarker of Diabetic Retinopathy

for Diabetic Retinopathy

3 sites incl. Carmel

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05079399

Apply to this trial

Sleep, Diabetic Retinopathy and Melatonin

for Diabetes Mellitus

1 site in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 40 - 65

Code: NCT04547439·Phase 2

Apply to this trial

MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema

for Diabetic Macular Edema

Sponsor: Shenzhen MingSight Relin Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT04187443·Phase 1

Apply to this trial

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

for Diabetic Retinopathy

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT04505618

Apply to this trial

Village-Integrated Eye Worker Trial II

for Age-related Macular Degeneration

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT03752840

Apply to this trial

Intraoperative OCT Guidance of Intraocular Surgery II

for Macular Holes

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 4 Weeks+·Accepts healthy volunteers

Code: NCT03713268

Apply to this trial

Soluble Cluster of Differentiation 160 (sCD160) in Sera and Intra-ocular Fluids: Association With Ischaemic Retinopathies

for Diabetic Retinopathy

Sponsor: CHU de Reims

Sex: All·Age: 18+

Code: NCT03680794

Apply to this trial

The Diabetic Retinopathy Screening, Prevention and Control Program

for Diabetic Retinopathy

Sponsor: Shanghai Jiao Tong University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04240652

Apply to this trial

Liver X Receptor (LXR) as a Novel Therapeutic Target in Diabetic Retinopathy (DR)

for Diabetic Retinopathy

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 21 - 98·Accepts healthy volunteers

Code: NCT03403686

Apply to this trial

Diabetic retinopathy clinical trials — common questions

Are diabetic retinopathy clinical trials free to join?

Yes. Participating in a diabetic retinopathy clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a diabetic retinopathy clinical trial?

Each diabetic retinopathy study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a diabetic retinopathy trial near me?

Use the location controls above. We'll show recruiting diabetic retinopathy trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many diabetic retinopathy trials are recruiting right now?

We're currently tracking roughly 21 recruiting diabetic retinopathy trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Diabetic retinopathy trials by city

Madison, WI Birmingham, AL San Francisco, CA Ann Arbor, MI Aurora, CO Beverly Hills, CA Carmel, IN Chicago, IL Glendale, CA Miami, FL

Related specialties

Ophthalmology Retina