Lupus (SLE) Clinical Trials
Recruiting lupus (sle) studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.
Clinical trials study new ways to prevent, detect, or treat lupus (sle). Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting lupus (sle) studies with sites across the US; use the location tools to find ones near you.
What to expect
- Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
- Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
- No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.
Recruiting lupus (sle) trials
Continued Access to Deucravacitinib for Adult SLE/SjD and Pediatric PsO/PsA Study Completers
Study to Characterise Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of Anifrolumab Administered Subcutaneously (SC) or Intravenously (IV)
Saphnelo Use in Females of Child-bearing Potential
A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body
A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune Diseases
Safety and Efficacy of ONT01 in Lupus
A Study of ATG-201 in Adult Participants With Autoimmune Diseases
SNC116 Therapy for Refractory Systemic Lupus Erythematosus
A Study to Test CRT-402 in Refractory Autoimmune Disease
SII and SIRI as Prognostic Biomarkers in Lupus Nephritis
A Study of QLS2404 Injection in Healthy Participants and Participants With Rheumatic Autoimmune Diseases
US Zamto-cel Autoimmune Diseases
A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy
A Study to Investigate Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Anifrolumab in Pediatric Participants 5 to < 18 Years of Age With Systemic Lupus Erythematosus
A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis
Therapeutic Drug Monitoring of Mycophenolate Mofetil in Lupus Nephritis
Immun4Cure Cohort of Autoimmune Diseases
A Clinical Trial on the Efficacy and Safety of TQH3906 in the Treatment of Systemic Lupus Erythematosus
Biomarker Development for Autoimmune Disorders Involving the Kidneys
Sirolimus in Patients With Systemic Lupus Erythematosus-Associated Immune Thrombocytopenia
Anifrolumab Pregnancy Study
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)
A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis
Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune Diseases
CHT105 for the Treatment of Refractory Lupus Nephritis
Ferroptosis Role in the Pathophysiology of Systemic Lupus Erythematosus
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus
A Phase 3 Clinical Study of MIL62 in Systemic Lupus Erythematosus
Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of Arnovie101, an mRNA-LNP-Based In Vivo CAR-T Therapy, for the Treatment of B Cell-Mediated Autoimmune Diseases (SLE and AIHA)
A Study of SHR-2173 in Participants With Systemic Lupus Erythematosus
Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases
A Study of E6742 in Participants With Systemic Lupus Erythematosus
MTS109 in Patients With Refractory Autoimmune Diseases
Alnuctamab for Refractory SLE (LATTE Study)
Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic (PK/PD) Profile of ACT100 in Healthy Participants..
Study of CD19 CAR-T Therapy for Refractory SLE
Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases
A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)
A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD)
A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)
A Prospective Comparative Study Involving Multiple Units to Evaluate the Efficacy and Safety of Telitacicept and Belimumab in the Treatment of Systemic Lupus Erythematosus.
Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE
A Study of CD19 UCAR-T Cells in Subjects With Autoimmune Diseases
Anifrolumab Malignancy and Serious Infections Study
Study of Ultra-Fast BCMA/CD70 CAR-T Therapy for Refractory SLE
Characterization of Autoreactive b Lymphocytes in Autoimmune Diseases and Immune Deficiencies
Prospective Registry Investigating Maternal, Infant, and Lactation Outcomes in Anifrolumab Users
A Study to Assess the Safety and PK/PD of LBL-047 in Healthy Adults and Patients With Systemic Lupus Erythematosus
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
Creating Health Course Study for People With Rheumatological Conditions and Mood Disorders
Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE
An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases
EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases
The Anifrolumab PRIM Program
UB-VV410 in Subjects With Active Refractory Systemic Lupus Erythematosus or Lupus Nephritis
Electromagnetic Immunotherapy Mapping and Cytokine Forecasting Study (QSIT)
The Diagnostic Utility of T Immunoglobulin G and T Immunoglobulin M Biomarkers in Patients With Systemic Lupus Erythematosus Disease : Associations With Disease Activity and Damage
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Lupus (SLE) clinical trials — common questions
Are lupus (sle) clinical trials free to join?
Yes. Participating in a lupus (sle) clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.
Who can join a lupus (sle) clinical trial?
Each lupus (sle) study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.
How do I find a lupus (sle) trial near me?
Use the location controls above. We'll show recruiting lupus (sle) trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.
How many lupus (sle) trials are recruiting right now?
We're currently tracking roughly 48 recruiting lupus (sle) trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.
Looking for a specific location? Browse trials by city and state.