Type 1 diabetes Clinical Trials

Recruiting type 1 diabetes studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat type 1 diabetes. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting type 1 diabetes studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting type 1 diabetes trials

Within

Technology Knowledge Optimization for Type 1 Diabetes in Schools

for Type 1 Diabetes (T1D)

1 site in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 5+

Code: NCT07482488

ENCRT-103-hPI: Evaluation of an Immune-protected ENCRT-103-hPI Containing Primary Human Islets in Adults With Type 1 Diabetes, With and Without Standard-of-care Portal Vein Islet Infusion.

for Type 1 Diabetes

Sponsor: Encellin

Sex: All·Age: 18 - 75

Code: NCT07680673·Phase 1

Sequential Immune Modulation and Antigen-Specific Tolerance Induction for Disease Modification in Recent-Onset Type 1 Diabetes

for Type 1 Diabetes Mellitus (T1DM)

Sponsor: Abdullah Kars

Sex: All·Age: 18 - 45

Code: NCT07610213·Phase 1

SHIELD-T1D: Shingrix and GLP-1 Agonist for Beta-Cell Preservation in Recent-Onset Type 1 Diabetes.

for Type 1 Diabetes Mellitus

Sponsor: Ministry of Health, Saudi Arabia

Sex: All·Age: 18 - 50

Code: NCT07614412·Phase 2

Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity

for Type 1 Diabetes Mellitus

Sponsor: Royal North Shore Hospital

Sex: All·Age: 18 - 70

Code: NCT06180616·Phase 2

Behavioural Problems and Cognition in Children With Hypoglycemia Unawareness in Type-1 Diabetes Mellitus

for Type 1 Diabetes

Sponsor: University of Pittsburgh

Sex: All·Age: 6 - 16

Code: NCT06488469

Evaluation of the Safety and Effectiveness of the Novel Medtronic Experimental Automated Insulin Delivery System (NMX8) in Adults Living With Type 1 Diabetes

for Type 1 Diabetes (T1D)

Sponsor: Medtronic MiniMed, Inc.

Sex: All·Age: 18+

Code: NCT07401901

How Abnormal Function of Fat Tissue in Type 1 Diabetes Contributes to Fat in the Liver

for Metabolic Dysfunction-Associated Steatotic Liver Disease

Sponsor: Université de Sherbrooke

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07133854

Targeting GLUT1 to Control Autoimmunity in Type 1 Diabetes

for Type 1 Diabetes

Sponsor: IRCCS San Raffaele

Sex: All·Age: 18+

Code: NCT07695727

Screening For Social Determinants Of Health In Routine Diabetes Care

for Type 1 Diabetes

1 site in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: Up to 21

Code: NCT07706803

Butyrate or Intensive Lifestyle Modification in Type 1 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease

for Type 1 Diabetes

Sponsor: Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud

Sex: All·Age: 18 - 75

Code: NCT07684248

Therapeutic Outcomes of Using Complementary Hand-based Treatment in Diabetes

for Diabetes Mellitus, Type 1

Sponsor: University Hospital, Linkoeping

Sex: All·Age: 18+

Code: NCT07275086

Precision T1D Platform - New Therapies for Cardio-Renal Complications

for Type 1 Diabetes

2 sites incl. Ann Arbor

Sponsor: Oregon Health and Science University

Sex: All·Age: 18 - 75

Code: NCT07594145·Phase 2

PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study

for Type 1 Diabetes (T1D)

4 sites incl. San Francisco

Sponsor: University of Florida

Sex: All·Age: 5 - 40

Code: NCT07670650·Phase 3

Feasibility and Effectiveness of an AI-Powered Carbohydrate Counting Educational Platform to Support Parents of Children With Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sponsor: Sultan Qaboos University

Sex: All·Age: All ages

Code: NCT07671053

Safety and Performance Evaluation of the SAVA Continuous Glucose Monitor for Effective Glucose Detection

for Type 1 Diabetes Mellitus

Sponsor: SAVA Technologies Ltd.

Sex: All·Age: 18+

Code: NCT07679347

Platform Trial in Stage 1 Diabetes: Comparing Golimumab vs Placebo

for Type 1 Diabetes (T1D)

1 site in Boston

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 2 - 44

Code: NCT07683026·Phase 2

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes Who Are Using Hybrid Closed Loop (HCL) Systems

for Type 1 Diabetes (T1D)

1 site in Atlanta

Sponsor: vTv Therapeutics

Sex: All·Age: 18+

Code: NCT07616206·Phase 2

Closed Loop Glucose Control in a Simulated ICU Setting

for Type 1 Diabetes

Sponsor: Ideal Medical Technologies

Sex: All·Age: 18 - 70

Code: NCT07646067

M1no-Study - Early Identification of Infants With High Type 1 Diabetes Risk for Participation in Primary Prevention Trials

for Type 1 Diabetes

Sponsor: IRCCS San Raffaele

Sex: All·Age: 0 Weeks - 6 Weeks·Accepts healthy volunteers

Code: NCT07670143

Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG

for Type 1 Diabetes Mellitus

1 site in Gainesville

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 4 - 34

Code: NCT07216391·Phase 2

Universal Type 1 Diabetes Screening in Pediatrics

for Type 1 Diabetes (T1D)

Sponsor: Northwestern University

Sex: All·Age: 1+

Code: NCT07612475

Think-Find-Solve Activities for Insulin Self-Management in Type 1 Diabetes

for Type 1 Diabetes

Sponsor: Marmara University

Sex: All·Age: 8 - 12

Code: NCT07670572

Dietary Approaches for the Management of Overweight and Obesity in Type 1 Diabetes

for Type 1 Diabetes (T1D)

Sponsor: Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud

Sex: All·Age: 18 - 65

Code: NCT07667504

Apply to this trial

Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sponsor: Victor Chang Cardiac Research Institute

Sex: All·Age: 18 - 65

Code: NCT06820281·Phase 2

Pediatric Artificial Intelligence for Retinopathy Screening in Children With Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sponsor: University Hospital, Motol

Sex: All·Age: 11 - 19

Code: NCT07149142

Apply to this trial

CKM For Safe Use of SGLT2i in Type 1 Diabetes

for Type 1 Diabetes (T1D)

1 site in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT07211802·Phase 3

NOURISH - A Healthcare-community Partnership to Improve Nutrition for Optimal Glycemic Control and Pregnancy Outcomes With Pregestational Diabetes

for Type 2 Diabetes

1 site in Columbus

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT07560813

Effect of a Structured Educational Intervention Through Mobile App on Hemoglobin A1c (HbA1c), Self-Efficacy and Self- Care in Adolescent With Type 1 Diabetes (T1DM)

for Type 1 Diabetes (Juvenile Onset)

Sponsor: Shifa Tameer-e-Millat University

Sex: All·Age: 10 - 19

Code: NCT07689318

Feasibility Study of a Continuous Glucose-Ketone Monitoring Device in People With Type 1 Diabetes

for Type 1 Diabetes (T1D)

1 site in Palo Alto

Sponsor: Mahla Poudineh

Sex: All·Age: 18 - 65

Code: NCT06977633

Reducing Risk of Diabetic Ketoacidosis in Type 1 Diabetes and Kidney Disease Using Continuous Ketone Monitoring

for Type 1 Diabetes Mellitus

1 site in Minneapolis

Sponsor: HealthPartners Institute

Sex: All·Age: 18 - 75

Code: NCT07325201·Phase 2

Ketone Monitoring Approaches for Diabetic Ketoacidosis Risk Mitigation in People With T1D on Adjunctive SGLT-2 Inhibitors

for Type 1 Diabetes

1 site in Orlando

Sponsor: AdventHealth Translational Research Institute

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07421518·Phase 2

Integrating New Skills Into Diabetes Education With CGM

for Insulin Dependent Diabetes

1 site in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 65+

Code: NCT07463209

Diabetes Multimorbidity Typology, Trajectory, and Feasibility of an Audio Diary Mobile Application to Support Self-management

for Diabetes Mellitus, Type 2

1 site in Atlanta

Sponsor: Emory University

Sex: All·Age: 65+

Code: NCT07474376

Apply to this trial

Finding Immune Nascent Type 1 Diabetes

for Healthy Adult

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 1 - 99·Accepts healthy volunteers

Code: NCT07663136

METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)

for Type 1 Diabetes (T1D)

1 site in Seattle

Sponsor: University of Washington

Sex: All·Age: 18 - 69

Code: NCT07699380·Phase 2

Apply to this trial

Impact of Insulin Deprivation and Hyperglycemia on Plasma Protein Synthesis in People With Type 1 Diabetes Mellitus

for Type 1 Diabetes

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT05985135

Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D)

for Non-Nutritive Sweetener

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 15 - 24

Code: NCT07434544

Individualized Exercise Consultation in Type 1 Diabetes

for Type 1 Diabetes

Sponsor: University of Aarhus

Sex: All·Age: 18+

Code: NCT07596160

Impact of Dietary Fat and Menstrual Cycle Phases in Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sponsor: Instituto de Investigacion Sanitaria La Fe

Sex: All·Age: 18 - 45

Code: NCT07278063

Standardized Italian netwoRk Enrolling iNdividuals With Islet-Autoantibodies

for Type 1 Diabetes (T1D)

Sponsor: Società Italiana di Endocrinologia e Diabetologia Pediatrica

Sex: All·Age: All ages

Code: NCT07503366

Effect of 4 Weeks of Oral Probiotic Desulfovibrio Piger Supplementation on Immunological and Metabolic Parameters in Individuals With Longstanding Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Sex: All·Age: 18+

Code: NCT07585994

Apply to this trial

"Ultrasound-Enhanced Propolis Therapy for Healing Diabetic Foot Wounds"

for Diabetic Foot Ulcer t

Sponsor: Sinai University

Sex: All·Age: 18 - 75

Code: NCT07099482

Pilot of Food Is Medicine Interventions to Reduce Cardiovascular Disease Risk in Children With Food Insecurity and Diabetes

for Type 1 Diabetes (T1D)

1 site in Providence

Sponsor: Katelyn Fox

Sex: All·Age: 5 - 12

Code: NCT07590817

Bioavailability, Biopotency and Food Effect Study of SCD0503 Compared to Subcutaneous Regular Human Insulin

for Diabetes Mellitus, Type 1

Sponsor: Sam Chun Dang Pharm. Co. Ltd.

Sex: Male·Age: 18 - 64

Code: NCT07634770·Phase 1

Apply to this trial

Evaluating Glucose Control Using a Next-Generation AID Algorithm in Individuals With T1D

for Type 1 Diabetes

Sponsor: Insulet Corporation

Sex: All·Age: 2 - 70·Accepts healthy volunteers

Code: NCT07593625

Apply to this trial

Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes

for Type 1 Diabetes (T1D)

4 sites incl. Detroit

Sponsor: DreaMed Diabetes

Sex: All·Age: 18 - 80

Code: NCT07599982

Apply to this trial

A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood Sugar

for Type 1 Diabetes

Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All·Age: 18+

Code: NCT07284511·Phase 2, Phase 3

Apply to this trial

Simultaneous Measurement and Responsive Treatment - Part 2

for Type 1 Diabetes Mellitus

Sponsor: ClinSurge Research

Sex: All·Age: 18+

Code: NCT07655076·EARLY_Phase 1

Apply to this trial

Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

for Type 1 Diabetes Mellitus

9 sites incl. Aurora

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 8 - 45

Code: NCT07142252·Phase 2

Apply to this trial

Insulin Delivery With Self-Adjusting Closed-Loop and Behavioral Glycemic Control Enhanced by Prediction

for Type 1 Diabetes (T1D)

1 site in Charlottesville

Sponsor: Sue Brown

Sex: All·Age: 18+

Code: NCT07507708

Apply to this trial

Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

for Type 2 Diabetes Mellitus

12 sites incl. Los Angeles

Sponsor: Insulet Corporation

Sex: All·Age: 14 - 75

Code: NCT07579702

Apply to this trial

A Research Study Investigating the Effect of NNC0497-0040 in Healthy Participants, Participants With Overweight or Obesity, and Participants With Type 1 Diabetes With Overweight or Obesity

for Type 1 Diabetes (T1D)

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18 - 55

Code: NCT07578584·Phase 1

Apply to this trial

Pediatric Insulin Plan Calculator for T1DM Management

for Type 1 Diabetes Mellitus

Sponsor: Sultan Qaboos University

Sex: All·Age: 1 - 12

Code: NCT07427134

Apply to this trial

Hypoglycemia Fear Affect Autonomic Function, Physical Activity, and Exercise Capacity in Type I Diabetes

for Type 1 Diabetes Mellitus

Sponsor: Ordu University

Sex: All·Age: 10 - 18

Code: NCT07527676

Glucose-lowering Drugs as an Adjunct to Insulin Therapy in Chinese Patients With Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT07415226

Adaptation of REDCHIP Intervention for the Portuguese Context

for Type 1 Diabetes

Sponsor: ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida

Sex: All·Age: 1 - 8

Code: NCT07201779

Using a Personalized Decision Support Tool to Help People With Type 1 Diabetes Manage Exercise

for Type 1 Diabetes Mellitis

1 site in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07226583

Study of IMC-S118AI in Type 1 Diabetes

for Type 1 Diabetes

Sponsor: Immunocore Ltd

Sex: All·Age: 18 - 45

Code: NCT07493122·Phase 1

Open-Label Study of Dimethyl Fumarate in Adults With Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sponsor: Nanjing Medical University

Sex: All·Age: 18 - 65

Code: NCT07548996·Phase 2, Phase 3

Apply to this trial

Type 1 diabetes clinical trials — common questions

Are type 1 diabetes clinical trials free to join?

Yes. Participating in a type 1 diabetes clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a type 1 diabetes clinical trial?

Each type 1 diabetes study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a type 1 diabetes trial near me?

Use the location controls above. We'll show recruiting type 1 diabetes trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many type 1 diabetes trials are recruiting right now?

We're currently tracking roughly 172 recruiting type 1 diabetes trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Type 1 diabetes trials by city

Aurora, CO Chicago, IL Boston, MA San Francisco, CA La Jolla, CA Los Angeles, CA Miami, FL Palo Alto, CA Cleveland, OH Duarte, CA Indianapolis, IN Orlando, FL

Related specialties

Endocrinology