Paid Clinical Trials in Baltimore, MD
As of June 2026, 1,638 paid clinical trials are recruiting in Baltimore, Maryland. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Baltimore offers studies at sites including Johns Hopkins University for conditions such as Breast Cancer, Prostate Cancer, Stroke, Heart Failure. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Baltimore
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Baltimore has approximately 1,638 recruiting research studies across a wide range of therapeutic areas. Maryland hosts Johns Hopkins Medicine and the NIH Clinical Center in Bethesda, giving participants access to some of the most advanced early-phase research in the country.
Top Research Study Locations in Baltimore
Researchers run research studies in Baltimore, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Johns Hopkins University | Cystic Fibrosis, Prostate Cancer, Achondroplasia | 189 |
| Johns Hopkins Hospital | Barrett Esophagus, Bladder Cancer, COVID-19 | 131 |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 70 |
| University of Maryland | Acute Kidney Injury, Carcinoma, Non-Small-Cell Lung, Multiple Myeloma | 64 |
| University of Maryland/Greenebaum Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Extensive Stage Lung Small Cell Carcinoma | 58 |
| University of Maryland Medical Center | Heart Failure, Subarachnoid Hemorrhage, Acute Kidney Injury | 57 |
| Sinai Hospital of Baltimore | Malignant Solid Neoplasm, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 53 |
| Johns Hopkins University School of Medicine | Alcohol Use Disorder, Amputation, Traumatic, Chronic Low-back Pain | 49 |
| Johns Hopkins | Primary Immune Deficiency Disorder, Chronic Obstructive Pulmonary Disease (COPD), Atrial Fibrillation | 42 |
| Johns Hopkins School of Medicine | Alzheimer Disease, Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy | 35 |
| Kennedy Krieger Institute | Autism Spectrum Disorder, Adrenomyeloneuropathy, Autism | 35 |
| Johns Hopkins Bayview Medical Center | Carcinoma, Non-Small-Cell Lung, Healthy, Sleep | 28 |
| University of Maryland School of Medicine | Acute-On-Chronic Liver Failure, Advanced or Metastatic Colorectal Cancer, Brain Injury | 25 |
| Greater Baltimore Medical Center | Breast Cancer, Amblyopia, Anatomic Stage I Breast Cancer AJCC v8 | 22 |
| The Johns Hopkins Hospital | Mitral Valve Regurgitation, Achilles Tendon Repairs/Reconstructions, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar) | 22 |
| Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD | Cognitive Impairment, Falls, Obesity | 20 |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Breast Cancer, Kaposi Sarcoma, Lymphoma | 19 |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Prostate Cancer, Kidney Cancer, Metastatic Castration-resistant Prostate Cancer | 17 |
| Mercy Medical Center | Breast Cancer, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 17 |
| University of Maryland, Baltimore | Fatigue, Stroke, ADPKD (Autosomal Dominant Polycystic Kidney Disease) | 16 |
| University of Maryland Greenebaum Comprehensive Cancer Center | Non Small Cell Lung Cancer, Small Cell Lung Cancer, Advanced Solid Tumor | 16 |
| Maryland Proton Treatment Center | Breast Cancer, Anatomic Stage IV Breast Cancer AJCC v8, Biliary Tract Cancer | 15 |
| John Hopkins University | Amyotrophic Lateral Sclerosis, ALL, Adult, AML | 14 |
| Johns Hopkins Medicine | Acute Kidney Injury, Aging, Alport Syndrome | 14 |
| National Institute on Drug Abuse | Alcohol Use Disorder, Normal Physiology, Healthy Volunteers | 14 |
Active & Upcoming Studies in Baltimore (2026)
Recruiting trials in Baltimore grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (453 active studies)
- Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer · Phase 1, Phase 2 · National Cancer Institute (NCI)
- A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC) · Phase 1 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Neurology & pain (122 active studies)
- A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep · Phase 1, Phase 2 · Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
- Impact of Exogenous Ketones on Sleep Apnea · Phase 1, Phase 2 · Johns Hopkins University
Cardiovascular (77 active studies)
Diabetes & metabolic (55 active studies)
- Continuous Glucose Monitors (CGMs) and Readmission Rates · University of Maryland, Baltimore
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Mental health & behavior (51 active studies)
- Facilitation to Increase Tobacco Treatment · VA Office of Research and Development
- The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens · Johns Hopkins University
HIV / STI (42 active studies)
- Decision Support Tool to Integrate PrEP Into Emergency Departments · Phase 1 · George Washington University
- ED Patient's Perceptions and Acceptability Toward a Novel POC HCV Viral Load Testing · Johns Hopkins University
Eye & vision (26 active studies)
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
- Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy · University of Maryland, Baltimore
Pediatric (22 active studies)
- Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children · Duke University
- Measuring Brain Changes Following Cognitive Intervention in Pediatric Patients With Brain Tumors · Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Vaccines (19 active studies)
- A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Immunogenicity of RSVPreF3 Vaccine in Immunocompromised Persons · Phase 2 · Johns Hopkins University
Common conditions studied in Baltimore
- Breast Cancer (25 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Prostate Cancer (21 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Stroke (20 active studies). Stroke trials test acute reperfusion strategies, neuroprotective agents, and rehabilitation technologies to improve recovery.
- Heart Failure (18 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Opioid Use Disorder (18 active studies). Opioid use disorder research tests extended-release medications, novel pharmacotherapies, and harm-reduction interventions.
- Bladder Cancer (13 active studies). Recruiting Bladder Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Baltimore
- Johns Hopkins University
- University of Maryland, Baltimore
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- National Cancer Institute (NCI)
- AstraZeneca
Local regulations and guidelines
Clinical trials in Maryland are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Maryland research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Baltimore. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Baltimore
Hipa.ai aggregates every recruiting study in Baltimore from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Baltimore?
There are approximately 1,638 recruiting clinical trials in Baltimore, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Baltimore pay participants?
Most recruiting trials in Baltimore compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Baltimore?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Baltimore?
The most common conditions under active study in Baltimore include Breast Cancer (25), Prostate Cancer (21), Stroke (20), Heart Failure (18), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Baltimore?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Baltimore on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Baltimore?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Baltimore?
Recruiting research sites in Baltimore include Johns Hopkins University, Johns Hopkins Hospital, Johns Hopkins University/Sidney Kimmel Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Baltimore right now?
The largest active categories in Baltimore are Cancer & tumors (453), Neurology & pain (122), Cardiovascular (77). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.