Oncology Clinical Trials in Baltimore, MD
As of August 2026, 259 paid clinical trials are recruiting for Oncology in Baltimore, Maryland. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Baltimore
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation
261 clinical trials for Oncology
·Clear filters·Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Top Research Study Locations in Baltimore
Researchers run research studies in Baltimore, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Johns Hopkins University | Cystic Fibrosis, Pancreatic Ductal Adenocarcinoma (PDAC), Prostate Cancer | 189 |
| Johns Hopkins Hospital | Barrett Esophagus, Bladder Cancer, Urothelial Cancer | 120 |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, B Acute Lymphoblastic Leukemia | 63 |
| University of Maryland | Acute Kidney Injury, Carcinoma, Non-Small-Cell Lung, Multiple Myeloma | 58 |
| University of Maryland Medical Center | Subarachnoid Hemorrhage, Acute Kidney Injury, Cardiomyopathies | 51 |
| Sinai Hospital of Baltimore | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, B Acute Lymphoblastic Leukemia | 49 |
| Johns Hopkins University School of Medicine | Alcohol Use Disorder, Amputation, Traumatic, Chronic Low-back Pain | 44 |
| University of Maryland/Greenebaum Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia | 43 |
| Johns Hopkins | Primary Immune Deficiency Disorder, Chronic Obstructive Pulmonary Disease (COPD), Atrial Fibrillation | 38 |
| Kennedy Krieger Institute | Adrenomyeloneuropathy, Autism Spectrum Disorder, Cerebral Palsy | 30 |
| Johns Hopkins School of Medicine | Alzheimer Disease, Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy | 29 |
| Johns Hopkins Bayview Medical Center | Carcinoma, Non-Small-Cell Lung, Healthy, Sleep | 26 |
| Greater Baltimore Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Amblyopia, Anatomic Stage IIIA Breast Cancer AJCC v8 | 21 |
| The Johns Hopkins Hospital | Achilles Tendon Repairs/Reconstructions, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Aortic Stenosis | 21 |
| Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD | Cognitive Impairment, Falls, Obesity | 20 |
| University of Maryland, Baltimore | Fatigue, Stroke, ADPKD (Autosomal Dominant Polycystic Kidney Disease) | 19 |
| Johns Hopkins Medicine | Achondroplasia, Acute Kidney Injury, Aging | 19 |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Breast Cancer, Kaposi Sarcoma, Lymphoma | 18 |
| University of Maryland School of Medicine | Acute-On-Chronic Liver Failure, Brain Injury, Caregiver Distress | 17 |
| John Hopkins University | Amyotrophic Lateral Sclerosis, Advanced Solid Tumors, Allogenic Transplant Patients | 16 |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Prostate Cancer, Kidney Cancer, Metastatic Castration-resistant Prostate Cancer | 16 |
| Mercy Medical Center | Breast Cancer, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 16 |
| National Institute on Drug Abuse | Normal Physiology, Alcohol Use Disorder, Substance Use Disorder | 14 |
| Maryland Proton Treatment Center | Breast Cancer, Anatomic Stage IV Breast Cancer AJCC v8, Biliary Tract Cancer | 13 |
| National Institute of Aging, Clinical Research Unit | Healthy Volunteers, Aging, Alzheimer's Disease | 13 |
Active & Upcoming Studies in Baltimore (2026)
Recruiting trials in Baltimore grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (418 active studies)
- A Study of Topical Duvelisib in Participants With Early-stage Mycosis Fungoides · Phase 1 · SecuraBio
- Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer · Phase 2 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Neurology & pain (115 active studies)
- Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea. · Phase 2 · Johns Hopkins University
- A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep · Phase 1, Phase 2 · Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Cardiovascular (73 active studies)
- Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART) · National Heart, Lung, and Blood Institute (NHLBI)
- Pulmonary Hypertension (PH) Biorepository for Translational Research · National Institutes of Health Clinical Center (CC)
Diabetes & metabolic (52 active studies)
- Integrating Free-choice Marketplace, dieTitian coacHing, cultuRally Tailored messagIng to improVE Blood Pressure · Johns Hopkins University
- Continuous Glucose Monitors (CGMs) and Readmission Rates · University of Maryland, Baltimore
Mental health & behavior (45 active studies)
- Duloxetine and aeRobic Exercise to Improve Function in VEterans With Knee Osteoarthritis (DRIVE) · Phase 2 · VA Office of Research and Development
- Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving · Phase 2, Phase 3 · Johns Hopkins University
HIV / STI (44 active studies)
- Decision Support Tool to Integrate PrEP Into Emergency Departments · Phase 1 · George Washington University
- ED Patient's Perceptions and Acceptability Toward a Novel POC HCV Viral Load Testing · Johns Hopkins University
Eye & vision (27 active studies)
- Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects · Phase 4 · University of Maryland, Baltimore
- Optic Nerve Head Strain in Non-glaucoma Subjects · EARLY_Phase 1 · Johns Hopkins University
Pediatric (22 active studies)
- Hypoxic Red Blood Cells in Sickle Cell Anemia · Hemanext
- Mobile Technology to Reduce Teen Substance Misuse · Evidence-Based Practice Institute, Seattle, WA
Vaccines (16 active studies)
- Safety and Immunogenicity of Chimeric Hemagglutinin mRNA Vaccine Candidates · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Common conditions studied in Baltimore
- Breast Cancer (22 active studies)
- Prostate Cancer (20 active studies)
- Stroke (17 active studies)
- Heart Failure (14 active studies)
- Opioid Use Disorder (14 active studies)
- Pancreatic Cancer (13 active studies)
Leading research sponsors in Baltimore
- Johns Hopkins University
- University of Maryland, Baltimore
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- National Cancer Institute (NCI)
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Baltimore?
There are approximately 1,543 recruiting clinical trials in Baltimore, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Baltimore pay participants?
Most recruiting trials in Baltimore compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Baltimore?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Baltimore?
The most common conditions under active study in Baltimore include Breast Cancer (22), Prostate Cancer (20), Stroke (17), Heart Failure (14), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Baltimore?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Baltimore on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Baltimore?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Baltimore?
Recruiting research sites in Baltimore include Johns Hopkins University, Johns Hopkins Hospital, Johns Hopkins University/Sidney Kimmel Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Baltimore right now?
The largest active categories in Baltimore are Cancer & tumors (418), Neurology & pain (115), Cardiovascular (73). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.