Paid Clinical Trials in Bethlehem, PA
As of June 2026, 110 paid clinical trials are recruiting in Bethlehem, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Bethlehem offers studies at sites including Lehigh Valley Hospital - Muhlenberg for conditions such as Anatomic Stage IV Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Lung Non-Small Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Bethlehem
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·Clear filters·↓ Download CSVAbout research studies in Bethlehem
Bethlehem has approximately 110 recruiting research studies across a wide range of therapeutic areas. Pennsylvania hosts UPenn's Perelman School of Medicine and Children's Hospital of Philadelphia — pioneers in CAR-T cell therapy — alongside UPMC, Thomas Jefferson University, and Penn State Hershey.
Top Research Study Locations in Bethlehem
Researchers run research studies in Bethlehem, PA at 27 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Lehigh Valley Hospital - Muhlenberg | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 51 |
| St. Luke's University Health Network | Abdominal Aortic Aneurysm, Adolescent Idiopathic Scoliosis, Advanced Ovarian Carcinoma | 15 |
| Saint Luke's University Hospital-Bethlehem Campus | Metastatic Malignant Neoplasm in the Brain, Pancreatic Neoplasm, Stage IV Lung Cancer AJCC v8 | 13 |
| Lehigh University | Parent-Child Relations, Parenting, Attention Deficit Hyperactivity Disorder | 5 |
| Northeast Clinical Research Center | Diabetic Kidney Disease (DKD), Focal Segmental Glomerulosclerosis, Proteinuric Kidney Diseases | 4 |
| Mid Atlantic Retina | Age-related Macular Degeneration (AMD), Geographic Atrophy (GA), Geographic Atrophy Secondary to Age-related Macular Degeneration | 3 |
| St. Luke's University Hospital | Pulmonary Embolism, Wound | 2 |
| Center for Specialized Surgery LP | Lumbar Spinal Stenosis | 1 |
| Lehigh Valley Health Network | Cancer, Myocarditis Acute | 1 |
| Lehigh Valley Hospital- Muhlenberg | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
| Mid Atlantic Retina - Bethlehem | Geographic Atrophy | 1 |
| Northeast Clinical Research Center, LLC | Atherosclerotic Cardiovascular Disease in Patients With ESKD | 1 |
| Saint Luke's Hospital of Bethlehem Pennsylvania | Ischemic Stroke | 1 |
| Saint Luke's University Hospital | Triple Negative Breast Cancer | 1 |
| Specialty Physician Associates | Obstructive Sleep Apnea of Adult | 1 |
| St Luke's University Health Network | NSCLC, Non-small Cell Lung Cancer | 1 |
| St Luke's University Health Network, Bethlehem Campus | Cutaneous Melanoma, Stage II | 1 |
| St Luke's University Hospital | Acute Kidney Injury | 1 |
| St. Luke'S Health Network | CRC (Colorectal Cancer) | 1 |
| St. Luke's Hospital | Breast Cancer | 1 |
| St. Luke's University Health Network (DNAanswers) | Genetic Predisposition to Disease, Genetics Disease | 1 |
| St. Luke's University Health Network - 1179 | Non Small Cell Lung Cancer | 1 |
| St. Lukes Hospital and Health Network | Carcinoma, Non-Small-Cell Lung | 1 |
| St. Lukes University Health Network | Ovarian Cancer | 1 |
| St. Lukes University Hospital | Epithelial Ovarian Cancer, Fallopian Tube Cancer, Neoadjuvant | 1 |
| TG Therapeutics Investigational Trial Site | Multiple Sclerosis, Relapsing Multiple Sclerosis | 1 |
| Valley Surgical Ctr | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in Bethlehem (2026)
Recruiting trials in Bethlehem grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (64 active studies)
- A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer · Phase 3 · Incyte Corporation
- Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays · Alliance for Clinical Trials in Oncology
Neurology & pain (3 active studies)
- A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS) · TG Therapeutics, Inc.
- Strategy for Improving Stroke Treatment Response · Phase 2 · Translational Sciences, Inc.
Cardiovascular (3 active studies)
Eye & vision (3 active studies)
- A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA) · Complement Therapeutics
- A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy · Phase 3 · Regeneron Pharmaceuticals
Mental health & behavior (2 active studies)
- Testing ANSOS for Efficacy in Multi-Tribal Urban Communities · Lehigh University
- Urban and Reservation Implementation of All Nations Breath of Life · Lehigh University
Pediatric (2 active studies)
- Hands and Hearts Together · University of Maryland, College Park
- Advanced SPinal Innovations With Robotics and Enabling Technology Registry · Boston Children's Hospital
Common conditions studied in Bethlehem
- Anatomic Stage IV Breast Cancer AJCC v8 (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Breast Cancer (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Lung Non-Small Cell Carcinoma (3 active studies). Recruiting Lung Non-Small Cell Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Malignant Solid Neoplasm (3 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Metastatic Malignant Neoplasm in the Brain (3 active studies). Recruiting Metastatic Malignant Neoplasm in the Brain studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Bethlehem
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- NRG Oncology
- Alliance for Clinical Trials in Oncology
- ECOG-ACRIN Cancer Research Group
Local regulations and guidelines
Clinical trials in Pennsylvania are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Pennsylvania research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Bethlehem. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Bethlehem
Hipa.ai aggregates every recruiting study in Bethlehem from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Bethlehem?
There are approximately 110 recruiting clinical trials in Bethlehem, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Bethlehem pay participants?
Most recruiting trials in Bethlehem compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Bethlehem?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Bethlehem?
The most common conditions under active study in Bethlehem include Anatomic Stage IV Breast Cancer AJCC v8 (4), Anatomic Stage II Breast Cancer AJCC v8 (3), Breast Cancer (3), Lung Non-Small Cell Carcinoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Bethlehem?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Bethlehem on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Bethlehem?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Bethlehem?
Recruiting research sites in Bethlehem include Lehigh Valley Hospital - Muhlenberg, St. Luke's University Health Network, Saint Luke's University Hospital-Bethlehem Campus, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Bethlehem right now?
The largest active categories in Bethlehem are Cancer & tumors (64), Neurology & pain (3), Cardiovascular (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.