Paid Clinical Trials in Sayre, PA
As of August 2026, 35 paid clinical trials are recruiting in Sayre, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Sayre offers studies at sites including Guthrie Medical Group PC-Robert Packer Hospital for conditions such as Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Advanced Breast Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Sayre
Trials by drug in Sayre
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Newly added in Sayre
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
34 clinical trials
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors
A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine
A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With HR+, HER2- Advanced Breast Cancer
Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease
The Lily Device Trial
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
Prehospital Analgesia INtervention Trial (PAIN)
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Frailty in Patients With Gastrointestinal Cancer Who Are Undergoing Major Surgery
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
Top Research Study Locations in Sayre
Researchers run research studies in Sayre, PA at 13 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Guthrie Medical Group PC-Robert Packer Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 14 |
| Guthrie Robert Packer Hospital | Traumatic Injury, Hypothyroidism, Non-Small Cell Lung Cancer | 4 |
| Guthrie Medical Group | Advanced Breast Cancer, Lung Cancer Diagnosis, Pneumococcal Disease | 3 |
| Clinical Trial Site | Breast Cancer, ER Positive Breast Cancer, HER2 Negative Breast Carcinoma | 2 |
| Donald Guthrie Foundation | Acute Myocardial Infarction, Pneumococcal Disease | 2 |
| Robert Packer Hospital | Gastrointestinal Cancer, Lyme Disease | 2 |
| Donald Guthrie Foundation - 1135 | Non Small Cell Lung Cancer | 1 |
| Guthrie | Extensive Stage Lung Small Cell Cancer | 1 |
| Guthrie Clinic | Chronic Renal Disease, End Stage Renal Disease (ESRD), Hemodialysis | 1 |
| Guthrie Clinical Research | Triple Negative Breast Cancer | 1 |
| Guthrie Medical Group, PC and Robert Packer Hospital (Guthrie Cancer Center - Sayre) | Gastric Cancer, Gastroesophageal-junction Cancer, HER2-positive Gastric Cancer | 1 |
| Guthrie Sayer Medical Centre | Chemotherapy Induced Alopecia | 1 |
| Guthrie Sayre | Breast Cancer | 1 |
Active & Upcoming Studies in Sayre (2026)
Recruiting trials in Sayre grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (26 active studies)
- A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With HR+, HER2- Advanced Breast Cancer · Phase 1 · TerSera Therapeutics LLC
- Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer · Phase 2 · PrECOG, LLC.
Vaccines (1 active study)
Common conditions studied in Sayre
- Breast Cancer (4 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Stage IIIB Lung Cancer AJCC v8 (3 active studies)
- Advanced Breast Cancer (2 active studies)
- Anatomic Stage I Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (2 active studies)
Leading research sponsors in Sayre
- National Cancer Institute (NCI)
- AbbVie
- Alliance for Clinical Trials in Oncology
- SWOG Cancer Research Network
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Sayre?
There are approximately 35 recruiting clinical trials in Sayre, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Sayre pay participants?
Most recruiting trials in Sayre compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Sayre?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Sayre?
The most common conditions under active study in Sayre include Breast Cancer (4), Anatomic Stage II Breast Cancer AJCC v8 (3), Stage IIIB Lung Cancer AJCC v8 (3), Advanced Breast Cancer (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Sayre?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Sayre on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Sayre?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Sayre?
Recruiting research sites in Sayre include Guthrie Medical Group PC-Robert Packer Hospital, Guthrie Robert Packer Hospital, Guthrie Medical Group, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Sayre right now?
The largest active categories in Sayre are Cancer & tumors (26), Vaccines (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.