Paid Clinical Trials in York, PA
As of August 2026, 94 paid clinical trials are recruiting in York, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
York offers studies at sites including Cancer Care Associates of York for conditions such as Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Coronary Artery Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in York
Trials by drug in York
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91 clinical trials
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
SELUTION 4 De Novo Small Vessel IDE Trial
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors
GEMINI-NSCLC: NSCLC Biomarker Study
TEMPUS ARIES: A Biobank Registry Platform Study in Oncology
FORWARD CAD IDE Study
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)
Prospective Study to Assess a Diagnostic Aid for Cancer
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)
C-Brace Prospective Registry
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis
Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)
A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)
Tempus Small Cell Lung Cancer Observational Study (Sculptor)
A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Helix Research Network
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm
CtDNA Based MRD Testing for NAC Monitoring in TNBC
A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies
Virtue® SAB in the Treatment of Coronary ISR Trial
Top Research Study Locations in York
Researchers run research studies in York, PA at 22 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cancer Care Associates of York | Cancer, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | 24 |
| WellSpan Health-York Cancer Center | Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 22 |
| WellSpan Health-York Hospital | Stage IV Lung Cancer AJCC v8, Metastatic Malignant Neoplasm in the Brain, Stage IIIB Lung Cancer AJCC v8 | 15 |
| UPMC Memorial | Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 14 |
| WellSpan Health | Acute Ischemic Stroke, Atrial Fibrillation, Coronary Artery Disease | 10 |
| WellSpan York Hospital | Aneurysm, Brain, Coronary Artery Disease, Osteoarthritis | 7 |
| Heart and Vascular Research at WellSpan Health | Atherosclerosis, Cardiovascular Diseases, Coronary Artery Disease | 2 |
| WellSpan Oncology Research | Carcinoma, Non-Small-Cell Lung, Non-Small Cell Lung Cancer (NSCLC) | 2 |
| WellSpan York Cancer Center | Advanced Malignant Neoplasm, Advanced Solid Tumor, Breast Cancer | 2 |
| York Hospital | Atrial Fibrillation, Coronary Arterial Disease (CAD), de Novo Lesions in Native Coronary Arteries | 2 |
| WellSpan Health York Hospital | Esophageal Foreign Body, Esophageal Obstruction, Rib Fracture Multiple | 2 |
| Ability x Ottobock.care | Lower Extremity, Pareses | 1 |
| Cancer Care Associates of York, Inc. | Breast Cancer | 1 |
| Cancer Care Associates of York, Inc. - 1113 | Non Small Cell Lung Cancer | 1 |
| Cancer Care Association of York | Small Cell Lung Cancer | 1 |
| MD@Home | Pharmacogenomic Testing for Medication Management | 1 |
| OSS Health Powder Mill | Lumbar Spinal Stenosis | 1 |
| WellSpan Health (The Gene Health Project) | Genetic Predisposition to Disease, Genetics Disease | 1 |
| WellSpan Health - York Cancer Center | Breast Carcinoma, Colorectal Carcinoma, Lung Non-Small Cell Carcinoma | 1 |
| WellSpan Health, York Hospital | Coronary Artery Disease (CAD), Coronary Calcification, Coronary Calcified Disease | 1 |
| WellSpan Heart and Vascular Research | Percutaneous Coronary Intervention, Peripheral Endovascular Intervention | 1 |
| Wellspan Gynecologic Oncology | Ovarian Cancer | 1 |
Active & Upcoming Studies in York (2026)
Recruiting trials in York grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (65 active studies)
- A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202) · Phase 3 · Bristol-Myers Squibb
- A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer · Phase 3 · Incyte Corporation
Cardiovascular (11 active studies)
Neurology & pain (2 active studies)
- Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial · Phase 3 · Mercy Health Ohio
- Stroke Thrombectomy and Aneurysm Registry · Medical University of South Carolina
Mental health & behavior (1 active study)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Common conditions studied in York
- Stage IV Lung Cancer AJCC v8 (6 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Breast Cancer (4 active studies)
- Coronary Artery Disease (4 active studies)
- Head and Neck Squamous Cell Carcinoma (4 active studies)
- Non-Small Cell Lung Cancer (4 active studies)
Leading research sponsors in York
- NRG Oncology
- AstraZeneca
- SWOG Cancer Research Network
- Tempus AI
- WellSpan Health
Frequently asked questions
How many paid clinical trials are currently recruiting in York?
There are approximately 94 recruiting clinical trials in York, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in York pay participants?
Most recruiting trials in York compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in York?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in York?
The most common conditions under active study in York include Stage IV Lung Cancer AJCC v8 (6), Anatomic Stage II Breast Cancer AJCC v8 (4), Breast Cancer (4), Coronary Artery Disease (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in York?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in York on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in York?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in York?
Recruiting research sites in York include Cancer Care Associates of York, WellSpan Health-York Cancer Center, WellSpan Health-York Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in York right now?
The largest active categories in York are Cancer & tumors (65), Cardiovascular (11), Neurology & pain (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.