MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
for Lumbar Spinal Stenosis
Sites in Wilkes-Barre, Kingston +2386 more locations
Sponsor: Stryker Instruments
Sex: All·Age: 18+
Code: NCT03072927·Recruiting·Listed Mar 2017
Paid Clinical Trials in Wilkes-Barre, PA
As of September 2026, 72 paid clinical trials are recruiting in Wilkes-Barre, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Wilkes-Barre offers studies at sites including Geisinger Wyoming Valley/Henry Cancer Center for conditions such as Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm, Lung Non-Small Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Wilkes-Barre
Trials by drug in Wilkes-Barre
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70 clinical trials
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A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
for Obstructive Hypertrophic Cardiomyopathy
Drug: Mavacamten
Sites in Wilkes-Barre, Bethlehem +46 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT05489705·Recruiting·Listed Aug 2022
Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts
for Cerebral Vasospasm
Sites in Wilkes-Barre, Pittsburgh +14 more locations
Sponsor: Vesalio
Sex: All·Age: 22+
Code: NCT06893588·Recruiting·Listed Mar 2025
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
for Ampulla of Vater Carcinoma
Sites in Wilkes-Barre, Dickson City +346 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07283939·Recruiting·Listed Dec 2025
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
Sites in Wilkes-Barre, Scranton +623 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Wilkes-Barre, Scranton +1087 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Wilkes-Barre, Scranton +923 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Wilkes-Barre, Scranton +626 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
Sites in Wilkes-Barre, East Stroudsburg +612 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting·Listed Apr 2022
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Wilkes-Barre, Dickson City +594 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
for Chronic Lymphocytic Leukemia
Sites in Wilkes-Barre, Danville +290 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Wilkes-Barre, Scranton +535 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
for Adenocarcinoma of the Colon
Sites in Wilkes-Barre, Scranton +331 more locations
Sponsor: NRG Oncology
Sex: All·Age: 45 - 70
Code: NCT05080673·Recruiting·Listed Oct 2021
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Wilkes-Barre, East Stroudsburg +482 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Wilkes-Barre, Scranton +777 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers
for Pancreatic Neoplasm
Sites in Wilkes-Barre, Stroudsburg +333 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 50 - 75
Code: NCT04239573·Recruiting·Listed Jan 2020
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
for Clear Cell Renal Cell Carcinoma
Sites in Wilkes-Barre, Scranton +401 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06661720·Phase 3·Recruiting·Listed Oct 2024
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
for Metastatic Renal Cell Carcinoma
Sites in Wilkes-Barre, Scranton +278 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05327686·Phase 2·Recruiting·Listed Apr 2022
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
for Locally Advanced Cervical Adenocarcinoma
Sites in Wilkes-Barre, Dickson City +318 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Wilkes-Barre, Scranton +328 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06203600·Phase 2, Phase 3·Recruiting·Listed Jan 2024
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
for Acute Myeloid Leukemia
Sites in Wilkes-Barre, Danville +324 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05564390·Phase 2·Recruiting·Listed Oct 2022
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program
for Cigarette Smoking-Related Carcinoma
Sites in Wilkes-Barre, Scranton +203 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05008848·Phase 3·Recruiting·Listed Aug 2021
Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy
for Anaplastic Large Cell Lymphoma, ALK-Negative
Sites in Wilkes-Barre, Danville +140 more locations
Sponsor: Eastern Cooperative Oncology Group
Sex: All·Age: 18 - 75
Code: NCT06724237·Phase 3·Recruiting·Listed Dec 2024
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Sites in Wilkes-Barre, Danville +203 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18 - 59
Code: NCT05554406·Phase 2·Recruiting·Listed Sep 2022
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Drug: Venetoclax
Sites in Wilkes-Barre, Danville +211 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06317649·Phase 2·Recruiting·Listed Mar 2024
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
for Locally Advanced Lung Non-Small Cell Carcinoma
Sites in Wilkes-Barre, Dickson City +444 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05624996·Phase 3·Recruiting·Listed Nov 2022
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma
Sites in Wilkes-Barre, Dickson City +324 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06958328·Phase 3·Recruiting·Listed May 2025
Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)
for Myelodysplastic Syndrome
Sites in Wilkes-Barre, Danville +136 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06577441·Phase 2·Recruiting·Listed Aug 2024
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Drug: Venetoclax
Sites in Wilkes-Barre, Danville +165 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18 - 59
Code: NCT05554393·Phase 2·Recruiting·Listed Sep 2022
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
for Advanced Hepatocellular Carcinoma
Sites in Wilkes-Barre, Dickson City +136 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT07166406·Phase 3·Recruiting·Listed Sep 2025
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
for Prostate Adenocarcinoma
Sites in Wilkes-Barre, Pottsville +397 more locations
Sponsor: NRG Oncology
Sex: Male·Age: 18+
Code: NCT05946213·Phase 3·Recruiting·Listed Jul 2023
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
for Acute Myeloid Leukemia
Sites in Wilkes-Barre, Danville +127 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06672146·Phase 2·Recruiting·Listed Nov 2024
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
for Locally Advanced Urothelial Carcinoma
Sites in Wilkes-Barre, Dickson City +157 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06524544·Phase 3·Recruiting·Listed Jul 2024
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
for Metastatic Colorectal Adenocarcinoma
Sites in Wilkes-Barre, Danville +163 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05673148·Phase 2·Recruiting·Listed Jan 2023
E-Mindfulness Approaches for Living After Breast Cancer
for Breast Cancer
Sites in Wilkes-Barre, Dickson City +372 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18 - 50
Code: NCT06748222·Phase 3·Recruiting·Listed Dec 2024
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery
for Grade 2 Meningioma
Sites in Wilkes-Barre, Pottsville +110 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT03180268·Phase 3·Recruiting·Listed Jun 2017
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma
for Recurrent Head and Neck Squamous Cell Carcinoma
Sites in Wilkes-Barre, Danville +125 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18 - 79
Code: NCT04671667·Phase 2·Recruiting·Listed Dec 2020
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial
for Non-Muscle Invasive Bladder Urothelial Carcinoma
Sites in Wilkes-Barre, Dickson City +133 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06770582·Phase 2·Recruiting·Listed Jan 2025
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
for Prostate Cancer (Adenocarcinoma)
Sites in Wilkes-Barre, Scranton +357 more locations
Sponsor: Canadian Cancer Trials Group
Sex: Male·Age: 18+
Code: NCT06592924·Phase 3·Recruiting·Listed Sep 2024
Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)
for Core Binding Factor Acute Myeloid Leukemia
Drug: Venetoclax
Sites in Wilkes-Barre, Danville +63 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18 - 59
Code: NCT06917911·Phase 2·Recruiting·Listed Apr 2025
Top Research Study Locations in Wilkes-Barre
Researchers run research studies in Wilkes-Barre, PA at 10 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Geisinger Wyoming Valley/Henry Cancer Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm | 60 |
| Geisinger Wyoming Valley | Cardiac Resynchronization Therapy, Heart Diseases, Heart Failure | 2 |
| Bucci Laser Vision Institute | IOL, Cataract | 1 |
| Geisinger | Aneurysmal Subarachnoid Hemorrhage (aSAH), Cerebral Vasospasm | 1 |
| Geisinger - Orthopaedics Wilkes-Barre | Osteoarthritis, Knee | 1 |
| Geisinger Health System | Obstructive Hypertrophic Cardiomyopathy | 1 |
| Geisinger Medical Group | Aneurysm, Brain, Stroke, Thromboses, Intracranial | 1 |
| Geisinger Wyoming Valley Medical Center | Tachyarrhythmia | 1 |
| Interventional & Surgical Suites of Wilkes - Barre, LLC | Lumbar Spinal Stenosis | 1 |
| Wilkes Barre General Hospital | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in Wilkes-Barre (2026)
Recruiting trials in Wilkes-Barre grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (53 active studies)
- Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial) · Phase 2 · National Cancer Institute (NCI)
- Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial · Phase 3 · NRG Oncology
Cardiovascular (4 active studies)
- Angiography and Electrogram Guided Bachmann Bundle Pacing · Pugazhendhi Vijayaraman
- His-Bundle Corrective Pacing in Heart Failure · University of Rochester
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program · Phase 3 · Alliance for Clinical Trials in Oncology
Neurology & pain (1 active study)
- Stroke Thrombectomy and Aneurysm Registry · Medical University of South Carolina
Eye & vision (1 active study)
- Clinical Outcomes of Patients with LAL+ in At Least One Eye · Frank A. Bucci, Jr., M.D.
Common conditions studied in Wilkes-Barre
- Acute Myeloid Leukemia (6 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Malignant Solid Neoplasm (4 active studies)
- Lung Non-Small Cell Carcinoma (3 active studies)
- Stage IV Lung Cancer AJCC v8 (3 active studies)
- Stage IVA Prostate Cancer AJCC v8 (3 active studies)
Leading research sponsors in Wilkes-Barre
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- NRG Oncology
- SWOG Cancer Research Network
- University of Rochester
Frequently asked questions
How many paid clinical trials are currently recruiting in Wilkes-Barre?
There are approximately 72 recruiting clinical trials in Wilkes-Barre, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Wilkes-Barre pay participants?
Most recruiting trials in Wilkes-Barre compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Wilkes-Barre?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Wilkes-Barre?
The most common conditions under active study in Wilkes-Barre include Acute Myeloid Leukemia (6), Anatomic Stage II Breast Cancer AJCC v8 (4), Malignant Solid Neoplasm (4), Lung Non-Small Cell Carcinoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Wilkes-Barre?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Wilkes-Barre on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Wilkes-Barre?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Wilkes-Barre?
Recruiting research sites in Wilkes-Barre include Geisinger Wyoming Valley/Henry Cancer Center, Geisinger Wyoming Valley, Bucci Laser Vision Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Wilkes-Barre right now?
The largest active categories in Wilkes-Barre are Cancer & tumors (53), Cardiovascular (4), Mental health & behavior (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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