Effects of Axatilimab on Skin in Chronic Graft-versus-Host Disease
for Chronic Graft vs. Host Disease
1 location in Chicago
Sponsor: Northwestern University
Sex: All·Age: 18+
Code: NCT07728708·Not Yet Recruiting·Listed Jul 27, 2026
Clinical Trials at Northwestern Medicine
As of August 2026, 17 paid clinical trials are recruiting at Northwestern Medicine, located at 150 E HURON ST, SUITE 1100, CHICAGO, IL 60611-2999, phone (312) 926-8400 in Chicago, Illinois. Active studies at this site cover conditions such as Breast Cancer, Obesity and Stroke. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Chicago
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
18 clinical trials at Northwestern Medicine
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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
for Triple Negative Breast Cancer
Sites in Chicago, Evanston +122 more locations
Sponsor: Gilead Sciences
Sex: All·Age: 18+
Code: NCT05633654·Phase 3·Recruiting·Listed Dec 2022
A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
for Endometrial Adenocarcinoma
Sites in Chicago, Urbana +40 more locations
Sponsor: Acrivon Therapeutics
Sex: Female·Age: 18+
Code: NCT05548296·Phase 2·Recruiting·Listed Sep 2022
GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections
for Aortic Dissection
Sites in Chicago +21 more locations
Sponsor: W.L.Gore & Associates
Sex: All·Age: 18+
Code: NCT06827990·Recruiting·Listed Feb 2025
The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms
for Hemorrhagic Stroke
Sites in Chicago, Park Ridge +20 more locations
Sponsor: phenox Inc.
Sex: All·Age: 18+
Code: NCT07143019·Recruiting·Listed Aug 2025
A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias
for High-risk Myelodysplastic Syndrome
Sites in Chicago +10 more locations
Sponsor: Crossbow Therapeutics, Inc.
Sex: All·Age: 12+
Code: NCT06994676·Phase 1·Recruiting·Listed May 2025
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
for Idiopathic Pulmonary Fibrosis
Sites in Chicago +18 more locations
Sponsor: Cumberland Pharmaceuticals
Sex: All·Age: 40+
Code: NCT05571059·Phase 2·Recruiting·Listed Oct 2022
A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma
for Glioblastoma Multiforme of Brain
Sites in Chicago +2 more locations
Sponsor: Tetragon Biosciences Ltd
Sex: All·Age: 18+
Code: NCT07464925·Phase 1·Recruiting·Listed Mar 2026
M-Vizion™ Macroscopic Radiographic Study
for Revision Hip Arthroplasty
Sites in Chicago +6 more locations
Sponsor: Medacta USA
Sex: All·Age: 21 - 80
Code: NCT05721859·Recruiting·Listed Feb 2023
Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
for Heart Failure With Preserved Ejection Fraction (HFpEF)
Sites in Chicago +1 more location
Sponsor: Secretome Therapeutics
Sex: All·Age: 18+
Code: NCT06560762·Phase 1·Recruiting·Listed Aug 2024
Increasing Germline Genetic Testing for Patients With Cancer
for Hereditary Pancreatic Cancer
Sites in Chicago +9 more locations
Sponsor: Josh Peterson
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT07307664·Recruiting·Listed Dec 2025
Real-component vs All-cement Articulating Spacers for Periprosthetic Knee Infection
for Prosthetic-joint Infection
1 location in Chicago
Sponsor: Northwestern University
Sex: All·Age: 18+
Code: NCT06293352·Recruiting·Listed Mar 2024
Telephone Support in Advanced Gastrointestinal Cancer
for Gastrointestinal Neoplasm Malignant
Sites in Chicago +3 more locations
Sponsor: Indiana University
Sex: All·Age: 18+
Code: NCT06532877·Recruiting·Listed Aug 2024
Novel Visual Education Tool to Improve Recognition and Reporting of Postpartum Urgent Maternal Warning Signs
for Postpartum
1 location in Chicago
Sponsor: Northwestern University
Sex: Female·Age: 18+
Code: NCT06912776·Recruiting·Listed Apr 2025
Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms
for Urinary Incontinence
1 location in Chicago
Sponsor: Northwestern University
Sex: Male·Age: 18 - 89
Code: NCT05878951·Phase 2, Phase 3·Recruiting·Listed May 2023
Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty
for Knee Osteoarthritis
1 location in Chicago
Sponsor: Northwestern University
Sex: All·Age: 21 - 79
Code: NCT06617871·Recruiting·Listed Oct 2024
Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation
for Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation
Drug: Durvalumab
Sites in Chicago +7 more locations
Sponsor: Institut de Recherches Internationales Servier
Sex: All·Age: 18+
Code: NCT06501625·Phase 1, Phase 2·Recruiting·Listed Jul 2024
Cardiogenic Shock Working Group Registry
for Cardiogenic Shock
Sites in Chicago +15 more locations
Sponsor: Tufts Medical Center
Sex: All·Age: 18+
Code: NCT04682483·Recruiting·Listed Dec 2020
Common conditions studied in Chicago
- Breast Cancer (35 active studies)
- Obesity (27 active studies)
- Stroke (25 active studies)
- Heart Failure (24 active studies)
- Acute Myeloid Leukemia (23 active studies)
- Hypertension (22 active studies)
Leading research sponsors in Chicago
- Northwestern University
- University of Chicago
- University of Illinois at Chicago
- National Cancer Institute (NCI)
- Rush University Medical Center
Frequently asked questions
How many paid clinical trials are currently recruiting in Chicago?
There are approximately 2,151 recruiting clinical trials in Chicago, Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Chicago pay participants?
Most recruiting trials in Chicago compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Chicago?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Chicago?
The most common conditions under active study in Chicago include Breast Cancer (35), Obesity (27), Stroke (25), Heart Failure (24), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Chicago?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Chicago on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Chicago?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Chicago?
Recruiting research sites in Chicago include Northwestern University, University of Chicago, Rush University Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Chicago right now?
The largest active categories in Chicago are Cancer & tumors (601), Neurology & pain (149), Cardiovascular (116). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Northwestern Medicine?
Northwestern Medicine is located at 150 E HURON ST, SUITE 1100, CHICAGO, IL 60611-2999. Use the Google Maps link in the intro above to get directions.
How do I contact Northwestern Medicine?
You can reach Northwestern Medicine by phone at (312) 926-8400. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
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