Paid Clinical Trials in Urbana, IL
As of August 2026, 141 paid clinical trials are recruiting in Urbana, Illinois. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Urbana offers studies at sites including Carle Cancer Center for conditions such as Stage IV Lung Cancer AJCC v8, Breast Cancer, Malignant Solid Neoplasm, Stage IVB Prostate Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Urbana
Trials by drug in Urbana
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136 clinical trials
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
SELUTION 4 De Novo Small Vessel IDE Trial
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib
Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
Exercise and Protein Efficiency in T2D
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Family Communications After Genetic Testing
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Diet Synergy in Muscle Protein Synthesis
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer
Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Top Research Study Locations in Urbana
Researchers run research studies in Urbana, IL at 22 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Carle Cancer Center | Stage IV Lung Cancer AJCC v8, Malignant Solid Neoplasm, Stage IVB Prostate Cancer AJCC v8 | 110 |
| The Carle Foundation Hospital | Metastatic Malignant Neoplasm in the Brain, Metastatic Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v8 | 23 |
| Carle Foundation Hospital | Coronary Artery Disease, Gynecologic Procedures, Hemiparetic Stroke | 7 |
| Freer Hall - University of Illinois | Control Condition, Glucose Metabolism, Obese Patients (BMI ≥ 30 kg/m²) | 2 |
| University of Illinois | Healthy Children, Tick Bites | 2 |
| University of Illinois Urbana-Champaign | Adults, Cognitive Change, EEG | 2 |
| University of Illinois at Urbana-Champaign | Aging, Cognitive Change, Diet, Healthy | 2 |
| Louise Freer Hall | Isotope Labeling, Muscle Health, Muscle Protein Synthesis | 1 |
| Carle Cancer Center NCI Community Oncology Research Program | Locally Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8 | 1 |
| Carle Cancer Institute | Carcinoma, Non-Small Cell Lung | 1 |
| Carle Founation Hospital | Epidermal Growth Factor Receptor Gene Mutation, Non Small Cell Lung Cancer, Stage III Lung Cancer | 1 |
| Carle Foundation Cancer Institute-Urbana | Breast Cancer, Breast Cancer Metastatic, Breast Neoplasm | 1 |
| Carle Foundation Hosp | Lumbar Spinal Stenosis | 1 |
| Carle Foundation Hospital d/b/a Carle Cancer Center | Breast Neoplasms | 1 |
| Carle Health | Alopecia, Breast Cancer, Chemotherapy-induced Alopecia | 1 |
| Clinical Trial Site | Breast Cancer, ER Positive Breast Cancer, HER2 Negative Breast Carcinoma | 1 |
| Disability Participation and Quality of Life (DPQOL) Laboratory | Multiple Sclerosis, Spinal Cord Injuries (SCI) | 1 |
| Local Institution - 0423 | Non-Small Cell Lung Cancer (NSCLC) | 1 |
| OSF Heart of Mary Medical Center | Lumbar Spinal Stenosis | 1 |
| TG Therapeutics Investigational Trial Site | Multiple Sclerosis, Relapsing Multiple Sclerosis | 1 |
| University of Illinois Extension | Relational Problems, Relationships, Marital | 1 |
| University of Illinois at Urbana Champaign | Sleeve Gastrectomy | 1 |
Active & Upcoming Studies in Urbana (2026)
Recruiting trials in Urbana grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (104 active studies)
- Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial · Phase 3 · National Cancer Institute (NCI)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
Neurology & pain (6 active studies)
- Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments · Carle Foundation Hospital
- Pain Management for In-Office Gynecologic Procedures Using a Risk-Stratification Pain Calculator · Carle Foundation Hospital
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program · Phase 3 · Alliance for Clinical Trials in Oncology
Diabetes & metabolic (2 active studies)
- Exercise and Protein Efficiency in T2D · University of Illinois at Urbana-Champaign
- Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL) · University of Illinois at Urbana-Champaign
Cardiovascular (2 active studies)
- SELUTION 4 De Novo Small Vessel IDE Trial · M.A. Med Alliance S.A.
- Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting · Philips Clinical & Medical Affairs Global
Pediatric (1 active study)
- Plants Optimizing Development Study (PODS) · University of Illinois at Urbana-Champaign
Common conditions studied in Urbana
- Stage IV Lung Cancer AJCC v8 (8 active studies)
- Breast Cancer (6 active studies)
- Malignant Solid Neoplasm (6 active studies)
- Stage IVB Prostate Cancer AJCC v8 (5 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Anatomic Stage IV Breast Cancer AJCC v8 (4 active studies)
Leading research sponsors in Urbana
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- NRG Oncology
- University of Illinois at Urbana-Champaign
Frequently asked questions
How many paid clinical trials are currently recruiting in Urbana?
There are approximately 141 recruiting clinical trials in Urbana, Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Urbana pay participants?
Most recruiting trials in Urbana compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Urbana?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Urbana?
The most common conditions under active study in Urbana include Stage IV Lung Cancer AJCC v8 (8), Breast Cancer (6), Malignant Solid Neoplasm (6), Stage IVB Prostate Cancer AJCC v8 (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Urbana?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Urbana on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Urbana?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Urbana?
Recruiting research sites in Urbana include Carle Cancer Center, The Carle Foundation Hospital, Carle Foundation Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Urbana right now?
The largest active categories in Urbana are Cancer & tumors (104), Neurology & pain (6), Mental health & behavior (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.