As of August 2026, 121 paid clinical trials are recruiting in O'Fallon, Illinois. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
O'Fallon offers studies at sites including Cancer Care Center of O'Fallon for conditions such as Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Researchers run research studies in O'Fallon, IL at 21 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cancer Care Center of O'Fallon | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 85 |
| HSHS Saint Elizabeth's Hospital | Stage IV Lung Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 54 |
| Cancer Care Specialists of Illinois | Breast Neoplasms, Cancer, Cancer of the Prostate | 4 |
| Cancer Care Specialists of Central Illinois | Breast Cancer, Multiple Myeloma, Squamous Cell Carcinoma of Head and Neck | 3 |
| Gateway Clinical Trials | Diabetic Foot Ulcer, Chronic Wound, Open Wound | 2 |
| HSHS St. Elizabeth's Hospital | Myasthenia Gravis | 2 |
| A53 | Myasthaenia Gravis | 1 |
| Cancer Care Specialist of Illinois | Breast Cancer, Early Stage Breast Cancer, HER2 + Breast Cancer | 1 |
| Cancer Care Specialists For Illinois | HR+/HER2- Breast Cancer | 1 |
| Cancer Care Specialists of Illinois - Cancer Care Center of O'Fallon | Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma | 1 |
| Clincial Research | Non-healing Wound, Venous Insufficiency of Leg, Venous Leg Ulcer | 1 |
| Clinical Res Ctr of S Illinois | Chronic Spontaneous Urticaria (CSU) | 1 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC) | 1 |
| HSHS Medical Group | New Onset Generalized Myasthenia Gravis (gMG) | 1 |
| HSHS Medical Group - St. Elizabeth's Hospital | Myasthenia Gravis, Generalized | 1 |
| HSHS St. Elizabeths Hospital | Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) | 1 |
| Hospital Sisters Health System (HSHS) - St Elizabeth's Hospital | Congenital Myasthenic Syndrome | 1 |
| Hospital Sisters Health System Medical | Generalized Myasthenia Gravis | 1 |
| Prairie Cardiovascular | Heart Failure With Reduced Ejection Fraction, Hypertension, Pulmonary | 1 |
| Prairie Education and Research Cooperative and HSHS Medical Group | Myasthenia Gravis | 1 |
| Prairie Education and Research Cooperative-St. Elizabeth's | Concentric Hypertrophy, Heart Failure With Preserved Ejection Fraction | 1 |
Recruiting trials in O'Fallon grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 121 recruiting clinical trials in O'Fallon, Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in O'Fallon compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in O'Fallon include Stage IV Lung Cancer AJCC v8 (8), Acute Myeloid Leukemia (5), Anatomic Stage II Breast Cancer AJCC v8 (5), Lung Non-Small Cell Carcinoma (5), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in O'Fallon on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in O'Fallon include Cancer Care Center of O'Fallon, HSHS Saint Elizabeth's Hospital, Cancer Care Specialists of Illinois, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in O'Fallon are Cancer & tumors (93), Mental health & behavior (2), Cardiovascular (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.