MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
for Lumbar Spinal Stenosis
Sites in Carbondale, Herrin +2367 more locations
Sponsor: Stryker Instruments
Sex: All·Age: 18+
Code: NCT03072927·Recruiting·Listed Mar 2017
Paid Clinical Trials in Carbondale, IL
As of August 2026, 37 paid clinical trials are recruiting in Carbondale, Illinois. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Carbondale offers studies at sites including Memorial Hospital of Carbondale for conditions such as Malignant Solid Neoplasm, Advanced Lung Non-Small Cell Carcinoma, Breast Cancer, Plasma Cell Myeloma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Carbondale
Trials by drug in Carbondale
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37 clinical trials
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Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies
for Breast Cancer
Sites in Carbondale, O'Fallon +12 more locations
Sponsor: Tempus AI
Sex: All·Age: 18 - 99
Code: NCT07211178·Recruiting·Listed Oct 2025
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
for Ampulla of Vater Carcinoma
Sites in Carbondale, Carterville +347 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07283939·Recruiting·Listed Dec 2025
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Carbondale, Carterville +1098 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Family Communications After Genetic Testing
for Colon Adenocarcinoma
Sites in Carbondale, Carterville +288 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07143487·Recruiting·Listed Aug 2025
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Carbondale, Carterville +913 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
for Intracranial Meningioma
Sites in Carbondale, Carterville +444 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
for Head and Neck Squamous Cell Carcinoma
Sites in Carbondale, Carterville +461 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT02734537·Phase 2·Recruiting·Listed Apr 2016
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Carbondale, Carterville +630 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
for Plasma Cell Myeloma
Sites in Carbondale, Carterville +303 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT04566328·Phase 3·Recruiting·Listed Sep 2020
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
Sites in Carbondale, Carterville +616 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting·Listed Apr 2022
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Carbondale, Carterville +482 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
for Miscellaneous Neoplasm, Nos
Sites in Carbondale, Carterville +276 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07091617·Recruiting·Listed Jul 2025
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers
for Metastatic Small Intestinal Adenocarcinoma
Sites in Carbondale, Carterville +397 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT04205968·Phase 2·Recruiting·Listed Dec 2019
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
for Fallopian Tube Endometrioid Adenocarcinoma
Drug: Bevacizumab
Sites in Carbondale, Carterville +653 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024
Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects
for Malignancy
Sites in Carbondale, Carterville +392 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: All ages
Code: NCT04242095·Recruiting·Listed Jan 2020
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
for Malignant Solid Neoplasm
Sites in Carbondale, Carterville +353 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT06295367·Recruiting·Listed Mar 2024
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in Carbondale, Carterville +206 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT07097142·Phase 3·Recruiting·Listed Jul 2025
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
for Biochemically Recurrent Prostate Carcinoma
Drug: Apalutamide
Sites in Carbondale, Carterville +276 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: Male·Age: 18+
Code: NCT04423211·Phase 3·Recruiting·Listed Jun 2020
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
for Childhood Extracranial Germ Cell Tumor
Sites in Carbondale, Carterville +385 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: All ages
Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017
Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change
for Advanced Lung Non-Small Cell Carcinoma
Drug: Osimertinib
Sites in Carbondale, Carterville +218 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03191149·Phase 2·Recruiting·Listed Jun 2017
Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors
for Hodgkin Lymphoma
Sites in Carbondale, Carterville +403 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT06002828·Recruiting·Listed Aug 2023
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
for Plasma Cell Myeloma
Sites in Carbondale, Carterville +387 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: All ages
Code: NCT05561387·Phase 3·Recruiting·Listed Sep 2022
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers
for Pancreatic Neoplasm
Sites in Carbondale, Carterville +334 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 50 - 75
Code: NCT04239573·Recruiting·Listed Jan 2020
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
for Locally Advanced Pancreatic Adenocarcinoma
Sites in Carbondale, Carterville +270 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT06998940·Phase 3·Recruiting·Listed May 2025
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
for Stroke
Sites in Carbondale, Park Ridge +38 more locations
Sponsor: Yale University
Sex: All·Age: 18+
Code: NCT05338697·Recruiting·Listed Apr 2022
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
for Malignant Solid Neoplasm
Sites in Carbondale, Carterville +586 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT04871542·Recruiting·Listed May 2021
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
for Stage I Breast Cancer
Sites in Carbondale, Carterville +705 more locations
Sponsor: NRG Oncology
Sex: All·Age: 50 - 70
Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
for Stroke
Sites in Carbondale, Chicago +26 more locations
Sponsor: Yale University
Sex: All·Age: 18+
Code: NCT05907629·Recruiting·Listed Jun 2023
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer
for Anatomic Stage IV Breast Cancer AJCC v8
Sites in Carbondale, Carterville +584 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT03723928·Recruiting·Listed Oct 2018
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
for Colorectal Cancer Stage II
Sites in Carbondale, Carterville +373 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07018869·Phase 3·Recruiting·Listed Jun 2025
Improving Safety, Patient Experience and Equity Through Shared Decision-making Huddles in Labor
for Perinatal Decision Making
Sites in Carbondale, Peoria +20 more locations
Sponsor: Endeavor Health
Sex: Female·Age: 18+·Accepts healthy volunteers
Code: NCT06828406·Recruiting·Listed Feb 2025
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Carbondale, Carterville +913 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
for Advanced Colorectal Carcinoma
Sites in Carbondale, Carterville +194 more locations
Sponsor: University of Rochester
Sex: All·Age: 18+
Code: NCT06073431·Recruiting·Listed Oct 2023
Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body
for Castration-Resistant Prostate Carcinoma
Sites in Carbondale, Carterville +172 more locations
Sponsor: SWOG Cancer Research Network
Sex: Male·Age: 18+
Code: NCT06470243·Phase 3·Recruiting·Listed Jun 2024
A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
for Acral Lentiginous Melanoma
Drug: Ipilimumab
Sites in Carbondale, Carterville +301 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT04511013·Phase 2·Recruiting·Listed Aug 2020
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
for Metastatic Clear Cell Renal Cell Carcinoma
Sites in Carbondale, Carterville +338 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT04510597·Phase 3·Recruiting·Listed Aug 2020
Top Research Study Locations in Carbondale
Researchers run research studies in Carbondale, IL at 4 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Memorial Hospital of Carbondale | Malignant Solid Neoplasm, Advanced Lung Non-Small Cell Carcinoma, Plasma Cell Myeloma | 34 |
| SIH Memorial Hospital of Carbondale | Intracranial Atherosclerotic Stenosis (ICAS), Stroke | 1 |
| Southern Illinois Healthcare Distribution Center | Lumbar Spinal Stenosis | 1 |
| Southern Illinois Hospital Services | Breast Cancer, Early Stage Breast Cancer, HER2 + Breast Cancer | 1 |
Active & Upcoming Studies in Carbondale (2026)
Recruiting trials in Carbondale grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (26 active studies)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
- Family Communications After Genetic Testing · Alliance for Clinical Trials in Oncology
Neurology & pain (2 active studies)
Common conditions studied in Carbondale
- Malignant Solid Neoplasm (3 active studies)
- Advanced Lung Non-Small Cell Carcinoma (2 active studies)
- Breast Cancer (2 active studies)
- Plasma Cell Myeloma (2 active studies)
- RISS Stage I Plasma Cell Myeloma (2 active studies)
- RISS Stage II Plasma Cell Myeloma (2 active studies)
Leading research sponsors in Carbondale
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- ECOG-ACRIN Cancer Research Group
- NRG Oncology
- Yale University
Frequently asked questions
How many paid clinical trials are currently recruiting in Carbondale?
There are approximately 37 recruiting clinical trials in Carbondale, Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Carbondale pay participants?
Most recruiting trials in Carbondale compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Carbondale?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Carbondale?
The most common conditions under active study in Carbondale include Malignant Solid Neoplasm (3), Advanced Lung Non-Small Cell Carcinoma (2), Breast Cancer (2), Plasma Cell Myeloma (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Carbondale?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Carbondale on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Carbondale?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Carbondale?
Recruiting research sites in Carbondale include Memorial Hospital of Carbondale, SIH Memorial Hospital of Carbondale, Southern Illinois Healthcare Distribution Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Carbondale right now?
The largest active categories in Carbondale are Cancer & tumors (26), Neurology & pain (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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