Biasing Food Value Construction
for Anorexia Nervosa
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 16 - 45·Accepts healthy volunteers
Code: NCT07692945·Not Yet Recruiting·Listed Jul 9, 2026
Clinical Trials at The University of Chicago
As of August 2026, 40 paid clinical trials are recruiting at The University of Chicago, located at 5841 S MARYLAND AVE, MC 5031, CHICAGO, IL 60637-1447, phone (773) 702-2048 in Chicago, Illinois. Active studies at this site cover conditions such as Breast Cancer, Obesity and Stroke. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Chicago
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
BRIDGE-US: Bridging Readiness in Deployed Neurotrauma Gaps for Excellence
for Brain Injuries, Acute
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 16+
Code: NCT07636213·Not Yet Recruiting·Listed Jun 2026
42 clinical trials at The University of Chicago
·Clear filters· Get a weekly email when new trials open in Chicago, IL.
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
for Age-related Macular Degeneration (AMD)
Drug: Cemdisiran
Sites in Chicago, Oak Park +139 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 50 - 85
Code: NCT06541704·Phase 3·Recruiting·Listed Aug 2024
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
for Solid Tumors
Sites in Chicago +41 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT03486873·Phase 3·Recruiting·Listed Apr 2018
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
for Carcinoma, Non-Small Cell Lung
Drug: sigvotatug vedotin
Sites in Chicago, Harvey +102 more locations
Sponsor: Seagen, a wholly owned subsidiary of Pfizer
Sex: All·Age: 18+
Code: NCT04389632·Phase 1·Recruiting·Listed May 2020
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
for Moderately to Severely Active Crohns Disease
Drug: Afimkibart
Sites in Chicago +58 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 16 - 80
Code: NCT06819891·Phase 3·Recruiting·Listed Feb 2025
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
for Hormone Receptor Positive HER-2 Negative Breast Cancer
Sites in Chicago +33 more locations
Sponsor: Puma Biotechnology, Inc.
Sex: All·Age: 18+
Code: NCT06369285·Phase 2·Recruiting·Listed Apr 2024
Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease
for cGVHD
Sites in Chicago, Maywood +29 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT05919511·Recruiting·Listed Jun 2023
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
for Aortic Dissection
Sites in Chicago +23 more locations
Sponsor: Endospan Ltd.
Sex: All·Age: 18+
Code: NCT04471909·Recruiting·Listed Jul 2020
Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment
for Parenteral Nutrition Associated Liver Disease (PNALD)
Sites in Chicago +9 more locations
Sponsor: Fresenius Kabi
Sex: All·Age: 1 Day - 17
Code: NCT06274788·Recruiting·Listed Feb 2024
Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors
for Neuroendocrine Tumors Unresectable
Sites in Chicago +18 more locations
Sponsor: Perspective Therapeutics
Sex: All·Age: 18 - 90
Code: NCT05636618·Phase 1, Phase 2·Recruiting·Listed Dec 2022
Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia
for AML With Gene Mutations
Sites in Chicago +11 more locations
Sponsor: Lomond Therapeutics Holdings, Inc.
Sex: All·Age: 18+
Code: NCT06366789·Phase 1·Recruiting·Listed Apr 2024
SMP-3124LP in Adults With Advanced Solid Tumors
for Solid Tumor
Sites in Chicago +9 more locations
Sponsor: Sumitomo Pharma America, Inc.
Sex: All·Age: 18+
Code: NCT06526819·Phase 1, Phase 2·Recruiting·Listed Jul 2024
Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients
for Malnutrition, Child
Sites in Chicago +4 more locations
Sponsor: Fresenius Kabi
Sex: All·Age: 1 Month - 17
Code: NCT06049680·Phase 4·Recruiting·Listed Sep 2023
A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers
for Oral Squamous Cell Carcinoma
Sites in Chicago +3 more locations
Sponsor: Privo Technologies
Sex: All·Age: 18 - 100
Code: NCT05893888·Phase 2, Phase 3·Recruiting·Listed Jun 2023
Breakthrough - T1DM and Chronic Kidney Disease
for Diabete Type 1
Sites in Chicago +1 more location
Sponsor: University of Chicago
Sex: All·Age: 18 - 70
Code: NCT07592000·Phase 1, Phase 2·Recruiting·Listed May 2026
Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial
for Osteomyelitis Tibia
Sites in Chicago +14 more locations
Sponsor: Wake Forest University Health Sciences
Sex: All·Age: 18+
Code: NCT05421741·Phase 4·Recruiting·Listed Jun 2022
A Study Comparing Two Immunotherapy Options for Human Papillomavirus Positive HPV-Positive Head and Neck Cancer After Treatment
for Head and Neck Cancer
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT07179315·Phase 2·Recruiting·Listed Sep 2025
Primary Subtalar Arthrodesis for Calcaneal Fractures
for Calcaneus Fracture
Sites in Chicago +16 more locations
Sponsor: Wake Forest University Health Sciences
Sex: All·Age: 18+
Code: NCT06249126·Recruiting·Listed Feb 2024
Cardiac Power Output in Cardiogenic Shock Patients
for Heart Failure
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT05700617·EARLY_Phase 1·Recruiting·Listed Jan 2023
Tissue Destruction and Healing in Celiac Disease
for Celiac Disease
Sites in Chicago +2 more locations
Sponsor: University of Chicago
Sex: All·Age: 18 - 75·Accepts healthy volunteers
Code: NCT05680012·Recruiting·Listed Jan 2023
Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites
for Nicotine Use Disorder
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18 - 26
Code: NCT06837220·Recruiting·Listed Feb 2025
The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer
for Rectal Cancer
Sites in Chicago +4 more locations
Sponsor: Weill Medical College of Cornell University
Sex: All·Age: 18 - 90
Code: NCT05943210·Recruiting·Listed Jul 2023
IMPRoving Outcomes in Vascular DisEase - Aortic Dissection
for Type B Aortic Dissection
Sites in Chicago, Springfield +50 more locations
Sponsor: Duke University
Sex: All·Age: 21+
Code: NCT06087029·Recruiting·Listed Oct 2023
Fecal Microbiota Transplant National Registry
for Fecal Microbiota Transplantation
Sites in Chicago, Maywood +26 more locations
Sponsor: American Gastroenterological Association
Sex: All·Age: All ages
Code: NCT03325855·Recruiting·Listed Oct 2017
Reducing Disparities in Urinary Control Symptoms for Minority Women
for Urinary Incontinence (UI)
2 locations in Chicago
Sponsor: University of Chicago
Sex: Female·Age: 18+
Code: NCT06798311·Recruiting·Listed Jan 2025
Response-Adaptive Treatment in Untreated Locoregional HPV-Negative Head and Neck Cancer
for Head and Neck Cancer
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT07065630·Phase 2·Recruiting·Listed Jul 2025
Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer
for Head and Neck Cancer
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT05526924·Phase 1·Recruiting·Listed Sep 2022
Dysbiosis & Long COVID
for COVID-19
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18 - 80·Accepts healthy volunteers
Code: NCT06825819·Recruiting·Listed Feb 2025
Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
for Atrial Fibrillation
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 20 - 85
Code: NCT06063538·EARLY_Phase 1·Recruiting·Listed Oct 2023
Posterior Rectus Sheath Hiatal Augmentation in Paraesophageal Hernia Repair
for Paraesophageal Hernia
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT06551077·Recruiting·Listed Aug 2024
Efficacy Of Hiatal Closure For GERD
for Gastro Esophageal Reflux
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18 - 50
Code: NCT06280664·Recruiting·Listed Feb 2024
Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation
for Obstructive Sleep Apnea
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06317701·Recruiting·Listed Mar 2024
MAsS Scan as a Predictor of Morbidity and Mortality in Patients With Liver Disease
for Liver Diseases
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT05264051·Recruiting·Listed Mar 2022
Explanted Lung Tissues With Pulmonary Fibrosis
for Pulmonary Fibrosis
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT00515567·Recruiting·Listed Aug 2007
Selumetinib and Azacitidine in High Risk Chronic Blood Cancers
for Chronic Myeloid Leukemia
Drug: Selumetinib
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT03326310·Phase 1·Recruiting·Listed Oct 2017
Immune Status After Being on Call for 24 Hrs
for Sleep Deprivation
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06636318·Recruiting·Listed Oct 2024
Islet Transplantation in Type 1 Diabetic Kidney Allograft
for Diabetes Mellitus, Type 1
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18 - 68
Code: NCT01241864·Phase 2·Recruiting·Listed Nov 2010
Quantitative Assessment of Autologous Fat Transfer
for Autologous Fat Grafting
Sites in Chicago +1 more location
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT06343831·Recruiting·Listed Apr 2024
Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy
for Gastric Cancers
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: All ages
Code: NCT01416714·Recruiting·Listed Aug 2011
Get Fit for Function
for Thoracic
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT06359652·Recruiting·Listed Apr 2024
Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies
for Pancreatic Adenocarcinoma
Drug: Irinotecan
1 location in Chicago
Sponsor: University of Chicago
Sex: All·Age: 18+
Code: NCT04361708·Phase 1·Recruiting·Listed Apr 2020
Common conditions studied in Chicago
- Breast Cancer (35 active studies)
- Obesity (27 active studies)
- Stroke (25 active studies)
- Heart Failure (24 active studies)
- Acute Myeloid Leukemia (23 active studies)
- Hypertension (22 active studies)
Leading research sponsors in Chicago
- Northwestern University
- University of Chicago
- University of Illinois at Chicago
- National Cancer Institute (NCI)
- Rush University Medical Center
Frequently asked questions
How many paid clinical trials are currently recruiting in Chicago?
There are approximately 2,151 recruiting clinical trials in Chicago, Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Chicago pay participants?
Most recruiting trials in Chicago compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Chicago?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Chicago?
The most common conditions under active study in Chicago include Breast Cancer (35), Obesity (27), Stroke (25), Heart Failure (24), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Chicago?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Chicago on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Chicago?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Chicago?
Recruiting research sites in Chicago include Northwestern University, University of Chicago, Rush University Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Chicago right now?
The largest active categories in Chicago are Cancer & tumors (601), Neurology & pain (149), Cardiovascular (116). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of The University of Chicago?
The University of Chicago is located at 5841 S MARYLAND AVE, MC 5031, CHICAGO, IL 60637-1447. Use the Google Maps link in the intro above to get directions.
How do I contact The University of Chicago?
You can reach The University of Chicago by phone at (773) 702-2048. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
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