Clinical Trials at The Cleveland Clinic Foundation
As of August 2026, 26 paid clinical trials are recruiting at The Cleveland Clinic Foundation, located at 9500 EUCLID AVE, CLEVELAND, OH 44195-0001, phone (216) 444-2200 in Cleveland, Ohio. Active studies at this site cover conditions such as Heart Failure, Breast Cancer and Advanced Solid Tumor. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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26 clinical trials at The Cleveland Clinic Foundation
·Clear filters·ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
PARTNER 3 Trial - Aortic Valve-in-Valve
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)
Abbott Cephea Mitral Valve Disease Registry
INHANCE Stemless Reverse Shoulder IDE
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)
Cephea Early Feasibility Study
Persona Revision Knee System Outcomes
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection
Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)
Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera
Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)
Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program
Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)
Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF Subjects
A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers
Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)
Laparoscopic Versus Robotic Lateral Transabdominal Adrenalectomy
Detecting Mild Autonomous Cortisol Secretion in Patients With Adrenal Incidentaloma
Common conditions studied in Cleveland
- Heart Failure (28 active studies)
- Breast Cancer (19 active studies)
- Advanced Solid Tumor (18 active studies)
- Cardiovascular Diseases (17 active studies)
- Prostate Cancer (16 active studies)
- Acute Myeloid Leukemia (15 active studies)
Leading research sponsors in Cleveland
- The Cleveland Clinic
- Case Comprehensive Cancer Center
- National Cancer Institute (NCI)
- University Hospitals Cleveland Medical Center
- Case Western Reserve University
Frequently asked questions
How many paid clinical trials are currently recruiting in Cleveland?
There are approximately 1,259 recruiting clinical trials in Cleveland, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Cleveland pay participants?
Most recruiting trials in Cleveland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Cleveland?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Cleveland?
The most common conditions under active study in Cleveland include Heart Failure (28), Breast Cancer (19), Advanced Solid Tumor (18), Cardiovascular Diseases (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Cleveland?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cleveland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Cleveland?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Cleveland?
Recruiting research sites in Cleveland include Cleveland Clinic, University Hospitals Cleveland Medical Center, Cleveland Clinic Foundation, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Cleveland right now?
The largest active categories in Cleveland are Cancer & tumors (384), Cardiovascular (103), Neurology & pain (85). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of The Cleveland Clinic Foundation?
The Cleveland Clinic Foundation is located at 9500 EUCLID AVE, CLEVELAND, OH 44195-0001. Use the Google Maps link in the intro above to get directions.
How do I contact The Cleveland Clinic Foundation?
You can reach The Cleveland Clinic Foundation by phone at (216) 444-2200. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.