Breast oncology Clinical Trials in Columbus, OH
As of August 2026, 38 paid clinical trials are recruiting for Breast oncology in Columbus, Ohio. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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38 clinical trials for Breast oncology
·Clear filters·Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer
BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
A Study of LY4175408 in Participants With Advanced Cancer
Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
Feasibility Study of CBCT for IGRT in Cancer Patients
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
A Pilot Study to Evaluate the Effectiveness of Focused Massage on Pain, Mobility, and Quality of Life During Radiation Treatment for Patients With Breast Cancer
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
E-Mindfulness Approaches for Living After Breast Cancer
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
ATEMPT 2.0: Adjuvant T-DM1 vs TH
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
The Sleep After Breast Cancer (ABC) Study - Examining Sleep Changes and Biomarkers Among Breast Cancer Patients
Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
Living Well With Advanced Breast Cancer
Impact of Dietary Inflammatory Potential on Breast Cancer Risk
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
The Ohio State University (OSU) SCREEN Community Program
Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry
Top Research Study Locations in Columbus
Researchers run research studies in Columbus, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Ohio State University Comprehensive Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Chronic Lymphocytic Leukemia | 244 |
| Nationwide Children's Hospital | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Surgery | 213 |
| The Ohio State University | Heart Failure, Prostate Cancer, Treatment Resistant Depression | 139 |
| Ohio State University | Colorectal Cancer, Coronary Artery Disease, Non-Small Cell Lung Cancer | 127 |
| The Ohio State University Wexner Medical Center | Follicular Lymphoma, Endometrial Cancer, Hypertension | 76 |
| Riverside Methodist Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 32 |
| Grant Medical Center | Anatomic Stage IV Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 26 |
| Ohio State University Wexner Medical Center | Anxiety, Chronic Nausea, Endometrial Cancer | 26 |
| Doctors Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 25 |
| The Ohio State University Comprehensive Cancer Center | Colorectal Cancer, Cancer, CRC | 23 |
| The Mark H Zangmeister Center | Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 22 |
| Mount Carmel East Hospital | Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8, Acral Lentiginous Melanoma | 21 |
| Columbus Oncology and Hematology Associates Inc | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 19 |
| Ohio State University Medical Center | AL Amyloidosis, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 17 |
| Mount Carmel Health Center West | Malignant Solid Neoplasm, Acral Lentiginous Melanoma, Acute Lymphoblastic Leukemia | 16 |
| OhioHealth Research Institute | Atrial Fibrillation, Acute Ischemic Stroke, Acute Myeloid Leukaemia (AML) | 13 |
| OSU Wexner Medical Center | Intracerebral Hemorrhage, Ischemic Stroke, Acute Hypoxic Respiratory Failure | 13 |
| The Ohio State University Medical Center | AADC Deficiency, Abdominal Aortic Aneurysm, Bone Marrow Transplant (BMT) | 11 |
| The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine | Pregnancy, High Risk, Preeclampsia, Gestational Hypertension | 10 |
| Clinical Trial Site | AQP4+ NMOSD, ATTR Amyloidosis, Breast Cancer | 9 |
| Ohio Health Research Institute | Aortic Dissection, Aortic Valve Disease, Aortic Valve Stenosis | 9 |
| GSK Investigational Site | Gastrointestinal Neoplasms, HIV Infections, Hypereosinophilic Syndrome | 8 |
| Nationwide Children's Hosptial | Primary Immune Deficiency Disorder, Adenovirus, Congenital Cytomegaloviral (CMV) Disease | 7 |
| OhioHealth Riverside Methodist Hospital | Aortic Stenosis, Carcinoma, Non-Small-Cell Lung, Coronary Artery Disease | 7 |
| Nationwide Children's | Acute Kidney Injury, Becker Muscular Dystrophy, Cardiomyopathy | 6 |
Active & Upcoming Studies in Columbus (2026)
Recruiting trials in Columbus grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (492 active studies)
- Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma · Phase 1 · Northwestern University
- Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital · Ohio State University Comprehensive Cancer Center
Cardiovascular (79 active studies)
- Health Coaching for Patients With Cardiovascular Disease · Ohio State University
- Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension · Ohio State University
Neurology & pain (65 active studies)
- Prescriptive Infusion Algorithm (PIA) · Phase 2 · AskBio Inc
- Stress, Coping, and Sleep Health Study · National Institute of Environmental Health Sciences (NIEHS)
Mental health & behavior (51 active studies)
- The Abuse Liability of IQOS Heated Tobacco Products Among Adults Who Smoke · Ohio State University Comprehensive Cancer Center
- VR for Steroid Joint Injections - Feasibility · Nationwide Children's Hospital
Diabetes & metabolic (40 active studies)
- Atomoxetine in Melanocortin Obesity Syndrome · Phase 2 · Icahn School of Medicine at Mount Sinai
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
Pediatric (36 active studies)
- Bilevel Positive Airway Pressure (BPAP) for Severe Asthma · Columbia University
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · Phase 2 · BrainChild Bio, Inc
HIV / STI (11 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
Vaccines (6 active studies)
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
- REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19 · Duke University
Eye & vision (6 active studies)
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
- A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK · Phase 3 · Kodiak Sciences Inc
Common conditions studied in Columbus
- Acute Myeloid Leukemia (20 active studies)
- Breast Cancer (19 active studies)
- Chronic Lymphocytic Leukemia (18 active studies)
- Ovarian Cancer (17 active studies)
- Endometrial Cancer (16 active studies)
- Malignant Solid Neoplasm (14 active studies)
Leading research sponsors in Columbus
- Ohio State University
- Ohio State University Comprehensive Cancer Center
- National Cancer Institute (NCI)
- Nationwide Children's Hospital
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Columbus?
There are approximately 1,365 recruiting clinical trials in Columbus, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Columbus pay participants?
Most recruiting trials in Columbus compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Columbus?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Columbus?
The most common conditions under active study in Columbus include Acute Myeloid Leukemia (20), Breast Cancer (19), Chronic Lymphocytic Leukemia (18), Ovarian Cancer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Columbus?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbus on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Columbus?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Columbus?
Recruiting research sites in Columbus include Ohio State University Comprehensive Cancer Center, Nationwide Children's Hospital, The Ohio State University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Columbus right now?
The largest active categories in Columbus are Cancer & tumors (492), Cardiovascular (79), Neurology & pain (65). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.