Heart2Heart for Teens With CHD
for Congenital Heart Disease
1 location in Columbus
Sponsor: Kristen Fox
Sex: All·Age: 12 - 18
Code: NCT07764510·Enrolling By Invitation·Listed Aug 14, 2026
Heart disease Clinical Trials in Columbus, OH
As of August 2026, 37 paid clinical trials are recruiting for Heart disease in Columbus, Ohio. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Columbus
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension
for Hypertension
1 location in Columbus
Sponsor: Ohio State University
Sex: All·Age: 18+
Code: NCT07679984·Not Yet Recruiting·Listed Jul 2026
39 clinical trials for Heart disease
·Clear filters· Email me when a new heart disease trial opens in Columbus, OH.
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
for Diabetes Mellitus, Type 2
Drug: Empagliflozin
Sites in Columbus, Cincinnati +202 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 18+
Code: NCT07064473·Phase 3·Recruiting·Listed Jul 2025
Assessment of CCM in HF With Higher Ejection Fraction
for Heart Failure
Sites in Columbus, Cleveland +74 more locations
Sponsor: Impulse Dynamics
Sex: All·Age: 18+
Code: NCT05064709·Recruiting·Listed Oct 2021
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
for Heart Failure
Sites in Columbus +31 more locations
Sponsor: Procyrion
Sex: All·Age: 21+
Code: NCT05677100·Recruiting·Listed Jan 2023
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
for High Risk Cardiovascular Disease
Drug: Zilebesiran
Sites in Columbus, Beavercreek +272 more locations
Sponsor: Alnylam Pharmaceuticals
Sex: All·Age: 18+
Code: NCT07181109·Phase 3·Recruiting·Listed Sep 2025
Prevail Global Study
for Coronary Artery Disease
Sites in Columbus, Cincinnati +49 more locations
Sponsor: Medtronic Vascular
Sex: All·Age: 18+
Code: NCT06535854·Recruiting·Listed Aug 2024
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
for Functional Mitral Regurgitation
Sites in Columbus, Dayton +49 more locations
Sponsor: Cardiac Dimensions, Inc.
Sex: All·Age: 18+
Code: NCT03142152·Recruiting·Listed May 2017
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
for Heart Failure
Sites in Columbus, Cincinnati +35 more locations
Sponsor: Cordio Medical
Sex: All·Age: 22+
Code: NCT06378632·Recruiting·Listed Apr 2024
Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)
for Coronary Artery Disease
Sites in Columbus +18 more locations
Sponsor: Supira Medical
Sex: All·Age: 18 - 90
Code: NCT07296744·Recruiting·Listed Dec 2025
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
for Atrial Fibrillation (AF)
Sites in Columbus, Cleveland +20 more locations
Sponsor: Medtronic Cardiac Ablation Solutions
Sex: All·Age: 18+
Code: NCT07298473·Recruiting·Listed Dec 2025
Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation
for Atrial Fibrillation (AF)
Sites in Columbus, Cincinnati +16 more locations
Sponsor: Arga Medtech SA
Sex: All·Age: 18 - 80
Code: NCT06784466·Recruiting·Listed Jan 2025
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study
for Atrial Fibrillation (AF)
Sites in Columbus, Toledo +10 more locations
Sponsor: Vektor Medical
Sex: All·Age: 22+
Code: NCT06935591·Recruiting·Listed Apr 2025
Pivotal Study for the Cardiac Performance System (CPS)
for Cardiovascular Diseases
Sites in Columbus +9 more locations
Sponsor: Sensydia Corporation
Sex: All·Age: 18+
Code: NCT06870591·Recruiting·Listed Mar 2025
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm
for Coronary Artery Disease
Sites in Columbus, Cincinnati +15 more locations
Sponsor: Kardion Inc
Sex: All·Age: 18 - 90
Code: NCT06445608·Recruiting·Listed Jun 2024
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study
for Congenital Heart Disease
Sites in Columbus, Cincinnati +6 more locations
Sponsor: Starlight Cardiovascular Inc
Sex: All·Age: 1 Minute - 6 Months
Code: NCT07114718·Recruiting·Listed Aug 2025
Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)
for Bradycardia
Sites in Columbus +6 more locations
Sponsor: VDI Technologies
Sex: All·Age: 18+
Code: NCT06641362·Recruiting·Listed Oct 2024
Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation
for Atrial Fibrillation
Sites in Columbus +3 more locations
Sponsor: Volta Medical
Sex: All·Age: 21+
Code: NCT06056271·Recruiting·Listed Sep 2023
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
for Atrial Fibrillation
Sites in Columbus, Wooster +85 more locations
Sponsor: Johns Hopkins University
Sex: All·Age: 22 - 85
Code: NCT05836987·Phase 3·Recruiting·Listed May 2023
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
for Cognitive Impairment, Mild
Sites in Columbus, Dayton +89 more locations
Sponsor: Duke University
Sex: All·Age: 75+·Accepts healthy volunteers
Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
for Intracerebral Hemorrhage
Sites in Columbus, Cincinnati +140 more locations
Sponsor: Yale University
Sex: All·Age: 18+
Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019
Ketogenic Diet vs Mixed Diet in Patients With Heart Failure
for Heart Failure With Preserved Ejection Fraction
1 location in Columbus
Sponsor: Ohio State University
Sex: All·Age: 18 - 80
Code: NCT06081543·Recruiting·Listed Oct 2023
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
for Heart Diseases
Sites in Columbus, Zanesville +39 more locations
Sponsor: Weill Medical College of Cornell University
Sex: Female·Age: 18+
Code: NCT04124120·Recruiting·Listed Oct 2019
Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients
for Diet, Food and Nutrition
1 location in Columbus
Sponsor: Ohio State University
Sex: All·Age: 60+
Code: NCT06586970·Recruiting·Listed Sep 2024
Genetics of Congenital Heart Disease
for Congenital Heart Disease
1 location in Columbus
Sponsor: Nationwide Children's Hospital
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT01192048·Recruiting·Listed Aug 2010
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
for Coronary Artery Disease
Sites in Columbus +17 more locations
Sponsor: Weill Medical College of Cornell University
Sex: All·Age: 18+
Code: NCT06399692·Phase 3·Recruiting·Listed May 2024
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities
for Coronary Artery Disease
Sites in Columbus +17 more locations
Sponsor: Weill Medical College of Cornell University
Sex: All·Age: 18+
Code: NCT06399705·Phase 3·Recruiting·Listed May 2024
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts
for HLH - Hypoplastic Left Heart Syndrome
1 location in Columbus
Sponsor: Nationwide Children's Hospital
Sex: All·Age: All ages
Code: NCT04467671·Phase 2·Recruiting·Listed Jul 2020
Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues
for Heart Failure
1 location in Columbus
Sponsor: Arunark Kolipaka
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT01757730·Recruiting·Listed Dec 2012
Effect of Fetal Aortic Valvuloplasty on Outcomes
for Congenital Heart Disease
Sites in Columbus +1 more location
Sponsor: Queen Silvia Children's Hospital, Gothenburg, Sweden
Sex: All·Age: 23 Weeks - 31 Weeks
Code: NCT05386173·Recruiting·Listed May 2022
IPSC Repository of Pediatric Cardiovascular Disease
for Congenital Heart Disease
1 location in Columbus
Sponsor: Mingtao Zhao
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT05550324·Recruiting·Listed Sep 2022
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
for Aortic Stenosis
Sites in Columbus, Akron +53 more locations
Sponsor: University of British Columbia
Sex: All·Age: All ages
Code: NCT04634240·Recruiting·Listed Nov 2020
Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease
for Adult Congenital Heart Disease
Sites in Columbus +2 more locations
Sponsor: Dartmouth-Hitchcock Medical Center
Sex: All·Age: 18+
Code: NCT06952933·Recruiting·Listed May 2025
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
for Cardiometabolic Syndrome
1 location in Columbus
Sponsor: Ohio State University
Sex: Male·Age: 18+
Code: NCT06055036·Recruiting·Listed Sep 2023
Autus Valve Continued Access Study (CAS)
for Congenital Heart Disease
Sites in Columbus +9 more locations
Sponsor: Edwards Lifesciences
Sex: All·Age: 18 Months - 16
Code: NCT07466745·Recruiting·Listed Mar 2026
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
for Cardiovascular Disease
Drug: AZD0780
Sites in Columbus, Lima +308 more locations
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT07000357·Phase 3·Recruiting·Listed Jun 2025
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
for Arrhythmia
Sites in Columbus, Cincinnati +82 more locations
Sponsor: Medtronic
Sex: All·Age: All ages
Code: NCT00271180·Recruiting·Listed Dec 2005
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
for Heart Failure
Drug: Dapagliflozin
Sites in Columbus, Beavercreek +175 more locations
Sponsor: AstraZeneca
Sex: All·Age: 40+
Code: NCT06677060·Phase 3·Recruiting·Listed Nov 2024
Product Surveillance Registry
for Cardiac Rhythm Disorders
Sites in Columbus, Dayton +127 more locations
Sponsor: Medtronic
Sex: All·Age: All ages
Code: NCT01524276·Recruiting·Listed Feb 2012
Top Research Study Locations in Columbus
Researchers run research studies in Columbus, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Ohio State University Comprehensive Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Chronic Lymphocytic Leukemia | 244 |
| Nationwide Children's Hospital | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Surgery | 213 |
| The Ohio State University | Heart Failure, Prostate Cancer, Treatment Resistant Depression | 139 |
| Ohio State University | Colorectal Cancer, Coronary Artery Disease, Non-Small Cell Lung Cancer | 127 |
| The Ohio State University Wexner Medical Center | Follicular Lymphoma, Endometrial Cancer, Hypertension | 76 |
| Riverside Methodist Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 32 |
| Grant Medical Center | Anatomic Stage IV Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 26 |
| Ohio State University Wexner Medical Center | Anxiety, Chronic Nausea, Endometrial Cancer | 26 |
| Doctors Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 25 |
| The Ohio State University Comprehensive Cancer Center | Colorectal Cancer, Cancer, CRC | 23 |
| The Mark H Zangmeister Center | Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 22 |
| Mount Carmel East Hospital | Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8, Acral Lentiginous Melanoma | 21 |
| Columbus Oncology and Hematology Associates Inc | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 19 |
| Ohio State University Medical Center | AL Amyloidosis, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 17 |
| Mount Carmel Health Center West | Malignant Solid Neoplasm, Acral Lentiginous Melanoma, Acute Lymphoblastic Leukemia | 16 |
| OhioHealth Research Institute | Atrial Fibrillation, Acute Ischemic Stroke, Acute Myeloid Leukaemia (AML) | 13 |
| OSU Wexner Medical Center | Intracerebral Hemorrhage, Ischemic Stroke, Acute Hypoxic Respiratory Failure | 13 |
| The Ohio State University Medical Center | AADC Deficiency, Abdominal Aortic Aneurysm, Bone Marrow Transplant (BMT) | 11 |
| The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine | Pregnancy, High Risk, Preeclampsia, Gestational Hypertension | 10 |
| Clinical Trial Site | AQP4+ NMOSD, ATTR Amyloidosis, Breast Cancer | 9 |
| Ohio Health Research Institute | Aortic Dissection, Aortic Valve Disease, Aortic Valve Stenosis | 9 |
| GSK Investigational Site | Gastrointestinal Neoplasms, HIV Infections, Hypereosinophilic Syndrome | 8 |
| Nationwide Children's Hosptial | Primary Immune Deficiency Disorder, Adenovirus, Congenital Cytomegaloviral (CMV) Disease | 7 |
| OhioHealth Riverside Methodist Hospital | Aortic Stenosis, Carcinoma, Non-Small-Cell Lung, Coronary Artery Disease | 7 |
| Nationwide Children's | Acute Kidney Injury, Becker Muscular Dystrophy, Cardiomyopathy | 6 |
Active & Upcoming Studies in Columbus (2026)
Recruiting trials in Columbus grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (492 active studies)
- Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma · Phase 1 · Northwestern University
- Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital · Ohio State University Comprehensive Cancer Center
Cardiovascular (79 active studies)
- Health Coaching for Patients With Cardiovascular Disease · Ohio State University
- Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension · Ohio State University
Neurology & pain (65 active studies)
- Prescriptive Infusion Algorithm (PIA) · Phase 2 · AskBio Inc
- Stress, Coping, and Sleep Health Study · National Institute of Environmental Health Sciences (NIEHS)
Mental health & behavior (51 active studies)
- The Abuse Liability of IQOS Heated Tobacco Products Among Adults Who Smoke · Ohio State University Comprehensive Cancer Center
- VR for Steroid Joint Injections - Feasibility · Nationwide Children's Hospital
Diabetes & metabolic (40 active studies)
- Atomoxetine in Melanocortin Obesity Syndrome · Phase 2 · Icahn School of Medicine at Mount Sinai
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
Pediatric (36 active studies)
- Bilevel Positive Airway Pressure (BPAP) for Severe Asthma · Columbia University
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · Phase 2 · BrainChild Bio, Inc
HIV / STI (11 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
Vaccines (6 active studies)
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
- REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19 · Duke University
Eye & vision (6 active studies)
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
- A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK · Phase 3 · Kodiak Sciences Inc
Common conditions studied in Columbus
- Acute Myeloid Leukemia (20 active studies)
- Breast Cancer (19 active studies)
- Chronic Lymphocytic Leukemia (18 active studies)
- Ovarian Cancer (17 active studies)
- Endometrial Cancer (16 active studies)
- Malignant Solid Neoplasm (14 active studies)
Leading research sponsors in Columbus
- Ohio State University
- Ohio State University Comprehensive Cancer Center
- National Cancer Institute (NCI)
- Nationwide Children's Hospital
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Columbus?
There are approximately 1,365 recruiting clinical trials in Columbus, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Columbus pay participants?
Most recruiting trials in Columbus compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Columbus?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Columbus?
The most common conditions under active study in Columbus include Acute Myeloid Leukemia (20), Breast Cancer (19), Chronic Lymphocytic Leukemia (18), Ovarian Cancer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Columbus?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbus on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Columbus?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Columbus?
Recruiting research sites in Columbus include Ohio State University Comprehensive Cancer Center, Nationwide Children's Hospital, The Ohio State University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Columbus right now?
The largest active categories in Columbus are Cancer & tumors (492), Cardiovascular (79), Neurology & pain (65). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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