Oncology Clinical Trials in Detroit, MI
As of August 2026, 202 paid clinical trials are recruiting for Oncology in Detroit, Michigan. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Detroit
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
203 clinical trials for Oncology
·Clear filters·A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies
A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
Top Research Study Locations in Detroit
Researchers run research studies in Detroit, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Henry Ford Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Heart Failure | 132 |
| Karmanos Cancer Institute | Ovarian Cancer, Advanced Solid Tumor, Endometrial Cancer | 89 |
| Henry Ford Health System | Advanced Solid Tumor, Brain Tumor, Breast Cancer | 68 |
| Henry Ford Health | Heart Failure, Advanced Solid Tumor, Amyotrophic Lateral Sclerosis | 58 |
| Children's Hospital of Michigan | Acute Myeloid Leukemia, Down Syndrome, Malignant Solid Neoplasm | 38 |
| Henry Ford Health Saint John Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 35 |
| Wayne State University/Karmanos Cancer Institute | Stage II Lip and Oral Cavity Cancer AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8 | 30 |
| Wayne State University | Asthma, Benign Prostatic Hyperplasia, Cancer Support | 20 |
| Barbara Ann Karmanos Cancer Institute | Breast Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms | 14 |
| Henry Ford Cancer Institute | Metastatic Solid Tumor, Locally Advanced Solid Tumor, AML | 12 |
| John D. Dingell VA Medical Center, Detroit, MI | Obstructive Sleep Apnea, Sleep Apnea, Sleep Disordered Breathing | 12 |
| GSK Investigational Site | Neoplasms, Colonic Neoplasms, Liver Diseases, Alcoholic | 8 |
| Karmanos Cancer Center | Breast Neoplasms, Cancer Weight Loss, Chronic Lymphocytic Leukemia (CLL) | 7 |
| Henry Ford Health Hospital | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 6 |
| Tolan Park Medical Building | PTSD, Polysubstance Abuse, Adolescence | 6 |
| Detroit Medical Center | Diabetes (DM), Diabetic Ketoacidosis, Gastric Emptying | 5 |
| Henry Ford | ADHF, Atrial Fibrillation (AF), Brain Tumor - Metastatic | 5 |
| Detroit Receiving Hospital | Traumatic Brain Injury, Lumbar Spinal Stenosis, Status Epilepticus | 4 |
| Henry Ford Cancer - Detroit (Brigitte Harris Cancer Pavilion) | Advanced Colorectal Cancer (Part 1), Glioma, KRAS G12C-mutated Solid Tumors, Lung Cancer | 4 |
| Henry Ford Cancer Center | Locally Advanced Solid Tumor, Hemoglobinopathy, Metastatic Solid Tumor | 4 |
| Henry Ford Medical Center | Acute Kidney Injury, Coronary Artery Disease, Healthy | 4 |
| Henry Ford St. John Hospital | Cardiovascular Diseases, Hypertension, Vascular Diseases | 4 |
| Ascension Saint John Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Elevated CA15-3 or CEA or CA27-29, Estrogen Receptor Positive | 3 |
| Ascension St. John Hospital | High-Risk Percutaneous Coronary Intervention, Pulmonary Embolism, Right Ventricular (RV) Dysfunction | 3 |
| Brigitte Harris Cancer Pavilion | Glioma, Melanoma, Thyroid Cancer | 3 |
Active & Upcoming Studies in Detroit (2026)
Recruiting trials in Detroit grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (304 active studies)
- Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1 · Phase 2 · Henry Ford Health System
- A Study of the TheraBionic P1 Device in Breast Cancer · Barbara Ann Karmanos Cancer Institute
Cardiovascular (51 active studies)
- Emergency Department-Initiated Team-Based Care for Severe Hypertension · Henry Ford Health System
- A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation · Phase 2 · Bayer
Neurology & pain (26 active studies)
- Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers · VA Office of Research and Development
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment · Phase 4 · VA Office of Research and Development
Diabetes & metabolic (15 active studies)
- Can Mindfulness and Virtual Reality Reduce Stress in Young Adults With Type 1 Diabetes? · Wayne State University
- Effects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver Disease · Henry Ford Health System
Mental health & behavior (11 active studies)
- Understanding Non-invasive Vagus Nerve Stimulation Effects in PTSD · EARLY_Phase 1 · Wayne State University
- Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery · Phase 1, Phase 2 · Leslie Lundahl
HIV / STI (4 active studies)
- Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention · Gilead Sciences
- A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062) · Phase 2, Phase 3 · Merck Sharp & Dohme LLC
Vaccines (3 active studies)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
- Predictors of Post-COVID-19 Clinical and Cognitive Consequences · VA Office of Research and Development
Eye & vision (3 active studies)
- Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries · Henry Ford Health System
- Community Based Treatment for (ComBaT) Glaucoma · University of Michigan
Pediatric (3 active studies)
- Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · Weill Medical College of Cornell University
- Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS · Phase 2, Phase 3 · Nationwide Children's Hospital
Common conditions studied in Detroit
- Endometrial Cancer (14 active studies)
- Advanced Solid Tumor (13 active studies)
- Breast Cancer (13 active studies)
- Heart Failure (13 active studies)
- Ovarian Cancer (12 active studies)
- Multiple Myeloma (11 active studies)
Leading research sponsors in Detroit
- Henry Ford Health System
- National Cancer Institute (NCI)
- AstraZeneca
- Wayne State University
- SWOG Cancer Research Network
Frequently asked questions
How many paid clinical trials are currently recruiting in Detroit?
There are approximately 718 recruiting clinical trials in Detroit, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Detroit pay participants?
Most recruiting trials in Detroit compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Detroit?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Detroit?
The most common conditions under active study in Detroit include Endometrial Cancer (14), Advanced Solid Tumor (13), Breast Cancer (13), Heart Failure (13), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Detroit?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Detroit on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Detroit?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Detroit?
Recruiting research sites in Detroit include Henry Ford Hospital, Karmanos Cancer Institute, Henry Ford Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Detroit right now?
The largest active categories in Detroit are Cancer & tumors (304), Cardiovascular (51), Neurology & pain (26). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.