GLP-1R Agonist Treatment for Opioid Use Disorder
for Opioid Use Disorder
3 locations incl. Baltimore
Sponsor: Milton S. Hershey Medical Center
Sex: All·Age: 18 - 75
Code: NCT06548490·Phase 2·Recruiting
Substance use disorder Clinical Trials in Harrisburg, PA
As of June 2026, 1 paid clinical trial is recruiting for Substance use disorder in Harrisburg, Pennsylvania. Recruiting Substance use disorder studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Harrisburg
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1 clinical trial for Substance use disorder
·Clear filters·↓ Download CSVAbout research studies in Harrisburg
Harrisburg has approximately 72 recruiting research studies across a wide range of therapeutic areas. Pennsylvania hosts UPenn's Perelman School of Medicine and Children's Hospital of Philadelphia — pioneers in CAR-T cell therapy — alongside UPMC, Thomas Jefferson University, and Penn State Hershey.
Top Research Study Locations in Harrisburg
Researchers run research studies in Harrisburg, PA at 27 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UPMC Pinnacle Cancer Center/Community Osteopathic Campus | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma | 33 |
| Susquehanna Research Group | Ankylosing Spondylitis, Autoimmune Diseases, Birdshot Chorioretinitis | 4 |
| UPMC Pinnacle Harrisburg | Anatomic Stage IV Breast Cancer AJCC v8, Diastolic Heart Failure, Elevated CA15-3 or CEA or CA27-29 | 4 |
| Pinnacle Health Cardiovascular Institute | Heart Failure, Peripheral Vascular Diseases | 3 |
| UPMC Harrisburg | Pulmonary Embolism, Cardiovascular Diseases, Hypertension | 3 |
| UPMC Pinnacle Harrisburg Campus | Coronary Artery Disease, Mitral Valve Regurgitation, Tricuspid Regurgitation | 3 |
| Pennsylvania Psychiatric Institute | Anxiety, Chemically-Induced Disorders, Chronic Stress | 2 |
| Susquehanna Research Group, LLC | Celiac Disease, Moderately to Severely Active Crohn Disease | 2 |
| UPMC Pinnacle | Tricuspid Valve Disease, Cardiovascular Diseases, Heart Failure | 2 |
| Investigational | Crohn's Disease, Ulcerative Colitis | 2 |
| Home-based telemedicine | Chronic Granulomatous Disease (CGD) | 1 |
| Latino Hispanic American Community Center | Advance Care Planning, Advance Directives, Chronic Illness | 1 |
| Magee-Woman's Hospital | Locally Advanced Solid Tumors, Metastatic Solid Tumors, Recurrent Solid Tumors | 1 |
| Parents and Children Together (PACT) Lab Space | Anxiety Symptoms, Conduct Problems, Depressive Symptoms | 1 |
| Penn State Health Medical Group - Andrews Patel | Breast Cancer | 1 |
| Penn State Health Medical Group - Andrews Patel Hematology/Oncology East | Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma, RISS Stage II Plasma Cell Myeloma | 1 |
| Penn State Hershey Medical Center-TLC Research and Treatment Center | Problematic Sexual Behavior Among Preteen Children | 1 |
| PennState Hershey Medical Center--PennState Health Children's Hospital | Hypoplastic Left Heart Syndrome (HLHS) | 1 |
| People's Community Baptist Church | Advance Care Planning, Advance Directives, Chronic Illness | 1 |
| Pinnacle Transplant Associates | Development of Reporting System for Molecular Diagnosis, Incorporate Molecular Diagnosis Into Diagnostic Standards, Validation Study of Molecular Diagnostic System | 1 |
| Susquehanna Research Group - Gastroenterology | C. Diff Infection, C.Difficile Diarrhea, CDI | 1 |
| Susquehanna Valley Pain Management | Lumbar Spinal Stenosis | 1 |
| UPMC Heart & Vascular Institute | Mitral Valve Insufficiency | 1 |
| UPMC Hillman Cancer Center - Pinnacle (Community Osteopathic / Medical Sciences Pavillion) | Colorectal Neoplasms | 1 |
| Univ of Pittsburg Med Ctr Pinnacle | Early Breast Cancer | 1 |
| University of Pittsburg Medical Center - Harrisburg | Distal Femur Fracture | 1 |
| University of Pittsburgh Medical Center | Kidney Transplant Rejection | 1 |
Active & Upcoming Studies in Harrisburg (2026)
Recruiting trials in Harrisburg grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (37 active studies)
- A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer · Phase 3 · National Cancer Institute (NCI)
- Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer · Phase 3 · National Cancer Institute (NCI)
Cardiovascular (8 active studies)
- Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System · P+F Products + Features USA Inc.
- Alleviant ALLAY-HFrEF Study · Alleviant Medical, Inc.
Mental health & behavior (4 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Video-feedback Intervention to Promote Racial-Ethnic Socialization Competency (VIP-RACE) · Penn State University
Neurology & pain (1 active study)
Pediatric (1 active study)
- Treatment for Problematic Sexual Behavior of Preteen Children · Milton S. Hershey Medical Center
Common conditions studied in Harrisburg
- Breast Cancer (5 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Heart Failure (4 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Head and Neck Squamous Cell Carcinoma (3 active studies). Recruiting Head and Neck Squamous Cell Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Prostate Adenocarcinoma (3 active studies). Recruiting Prostate Adenocarcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Stage IV Lung Cancer AJCC v8 (3 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
Leading research sponsors in Harrisburg
- NRG Oncology
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- ECOG-ACRIN Cancer Research Group
- Alliance for Clinical Trials in Oncology
Local regulations and guidelines
Clinical trials in Pennsylvania are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Pennsylvania research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Harrisburg. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Harrisburg
Hipa.ai aggregates every recruiting study in Harrisburg from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Harrisburg?
There are approximately 72 recruiting clinical trials in Harrisburg, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Harrisburg pay participants?
Most recruiting trials in Harrisburg compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Harrisburg?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Harrisburg?
The most common conditions under active study in Harrisburg include Breast Cancer (5), Heart Failure (4), Anatomic Stage II Breast Cancer AJCC v8 (3), Head and Neck Squamous Cell Carcinoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Harrisburg?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Harrisburg on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Harrisburg?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Harrisburg?
Recruiting research sites in Harrisburg include UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Susquehanna Research Group, UPMC Pinnacle Harrisburg, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Harrisburg right now?
The largest active categories in Harrisburg are Cancer & tumors (37), Cardiovascular (8), Mental health & behavior (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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