Paid Clinical Trials in Harrisburg, PA
As of July 2026, 62 paid clinical trials are recruiting in Harrisburg, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Harrisburg offers studies at sites including UPMC Pinnacle Cancer Center/Community Osteopathic Campus for conditions such as Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Head and Neck Squamous Cell Carcinoma, Heart Failure. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Harrisburg
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Researchers run research studies in Harrisburg, PA at 24 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UPMC Pinnacle Cancer Center/Community Osteopathic Campus | Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | 28 |
| Susquehanna Research Group | Ankylosing Spondylitis, Autoimmune Diseases, Birdshot Chorioretinitis | 4 |
| UPMC Pinnacle Harrisburg Campus | Coronary Artery Disease, Mitral Valve Regurgitation, Tricuspid Regurgitation | 3 |
| Pennsylvania Psychiatric Institute | Anxiety, Chemically-Induced Disorders, Chronic Stress | 2 |
| Pinnacle Health Cardiovascular Institute | Heart Failure | 2 |
| Susquehanna Research Group, LLC | Celiac Disease, Moderately to Severely Active Crohn Disease | 2 |
| UPMC Harrisburg | Cardiovascular Diseases, Hypertension, Pulmonary Embolism | 2 |
| UPMC Pinnacle | Tricuspid Valve Disease, Cardiovascular Diseases, Heart Failure | 2 |
| UPMC Pinnacle Harrisburg | Heart Valve Diseases, Previously Treated Non-Small Cell Lung Cancer, Tricuspid Regurgitation | 2 |
| Investigational | Crohn's Disease, Ulcerative Colitis | 2 |
| GSK Investigational Site | Irritable Bowel Syndrome | 1 |
| Home-based telemedicine | Chronic Granulomatous Disease (CGD) | 1 |
| Parents and Children Together (PACT) Lab Space | Anxiety Symptoms, Conduct Problems, Depressive Symptoms | 1 |
| Penn State Health Medical Group - Andrews Patel | Breast Cancer | 1 |
| Penn State Health Medical Group - Andrews Patel Hematology/Oncology East | Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma, RISS Stage II Plasma Cell Myeloma | 1 |
| Penn State Hershey Medical Center-TLC Research and Treatment Center | Problematic Sexual Behavior Among Preteen Children | 1 |
| PennState Hershey Medical Center--PennState Health Children's Hospital | Hypoplastic Left Heart Syndrome (HLHS) | 1 |
| Susquehanna Research Group - Gastroenterology | C. Diff Infection, C.Difficile Diarrhea, CDI | 1 |
| Susquehanna Valley Pain Management | Lumbar Spinal Stenosis | 1 |
| UPMC Heart & Vascular Institute | Mitral Valve Insufficiency | 1 |
| UPMC Hillman Cancer Center - Pinnacle (Community Osteopathic / Medical Sciences Pavillion) | Colorectal Neoplasms | 1 |
| Univ of Pittsburg Med Ctr Pinnacle | Early Breast Cancer | 1 |
| University of Pittsburg Medical Center - Harrisburg | Distal Femur Fracture | 1 |
| University of Pittsburgh Medical Center | Kidney Transplant Rejection | 1 |
Active & Upcoming Studies in Harrisburg (2026)
Recruiting trials in Harrisburg grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (32 active studies)
- A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer · Phase 3 · National Cancer Institute (NCI)
- Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer · Phase 3 · National Cancer Institute (NCI)
Cardiovascular (7 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- Alleviant ALLAY-HFrEF Study · Alleviant Medical, Inc.
Mental health & behavior (4 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Video-feedback Intervention to Promote Racial-Ethnic Socialization Competency (VIP-RACE) · Penn State University
Neurology & pain (1 active study)
Pediatric (1 active study)
- Treatment for Problematic Sexual Behavior of Preteen Children · Milton S. Hershey Medical Center
Common conditions studied in Harrisburg
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Breast Cancer (3 active studies)
- Head and Neck Squamous Cell Carcinoma (3 active studies)
- Heart Failure (3 active studies)
- Stage IV Lung Cancer AJCC v8 (3 active studies)
- Tricuspid Regurgitation (3 active studies)
Leading research sponsors in Harrisburg
- NRG Oncology
- National Cancer Institute (NCI)
- ECOG-ACRIN Cancer Research Group
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Harrisburg?
There are approximately 62 recruiting clinical trials in Harrisburg, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Harrisburg pay participants?
Most recruiting trials in Harrisburg compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Harrisburg?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Harrisburg?
The most common conditions under active study in Harrisburg include Anatomic Stage II Breast Cancer AJCC v8 (3), Breast Cancer (3), Head and Neck Squamous Cell Carcinoma (3), Heart Failure (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Harrisburg?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Harrisburg on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Harrisburg?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Harrisburg?
Recruiting research sites in Harrisburg include UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Susquehanna Research Group, UPMC Pinnacle Harrisburg Campus, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Harrisburg right now?
The largest active categories in Harrisburg are Cancer & tumors (32), Cardiovascular (7), Mental health & behavior (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.