Aging / healthy aging Clinical Trials in Hershey, PA
As of June 2026, 1 paid clinical trial is recruiting for Aging / healthy aging in Hershey, Pennsylvania. Healthy-volunteer studies examine how new drugs behave in the body, helping researchers understand safety and dosing before later-phase trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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1 clinical trial for Aging / healthy aging
·Clear filters·↓ Download CSVAbout research studies in Hershey
Hershey has approximately 292 recruiting research studies across a wide range of therapeutic areas. Pennsylvania hosts UPenn's Perelman School of Medicine and Children's Hospital of Philadelphia — pioneers in CAR-T cell therapy — alongside UPMC, Thomas Jefferson University, and Penn State Hershey.
Top Research Study Locations in Hershey
Researchers run research studies in Hershey, PA at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Penn State Milton S Hershey Medical Center | Acute Myeloid Leukemia, Breast Cancer, Anatomic Stage I Breast Cancer AJCC v8 | 44 |
| Penn State Milton S. Hershey Medical Center | Blood Pressure, Gastroesophageal Junction Adenocarcinoma, NSCLC | 25 |
| Penn State Children's Hospital | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 21 |
| Penn State Health Milton S. Hershey Medical Center | Alpha1-Antitrypsin Deficiency, Duchenne Muscular Dystrophy, Severe Alopecia Areata | 16 |
| Penn State College of Medicine | Anorexia Nervosa, Oxidative Stress, Tobacco Use | 14 |
| Penn State Health | Amyotrophic Lateral Sclerosis, Endometriosis, Heart Failure | 14 |
| Penn State Hershey Medical Center | Acute Kidney Injury (AKI), Acute Myocardial Infarction (AMI), Atrial Fibrillation | 13 |
| Penn State Milton S. Hershey Medical Center and Children's Hospital | Neuroblastoma, Ewing Sarcoma, Osteosarcoma | 10 |
| Penn State Cancer Institute | Breast Cancer, Allogeneic Stem Cell Transplantation, Chemotherapy-Induced Peripheral Neuropathy | 9 |
| Pennsylvania State University | Articular Fractures, Body Image, Body Image Disturbance | 8 |
| Milton S. Hershey Medical Center | Amyotrophic Lateral Sclerosis, Anxiety, Caregiver Burden | 6 |
| Penn State Milton S Hershey Medical Ctr | Multiple Myeloma, Colitis, Ulcerative, Crohn Disease | 5 |
| Penn State Health Milton South Hershey Medical Center | Chronic Inflammatory Demyelinating Polyneuropathy, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Polyneuropathy, Inflammatory Demyelinating, Chronic | 5 |
| Penn State Hershey | Amyotrophic Lateral Sclerosis, Epilepsy, Neurologic Disorder | 4 |
| Penn State University Milton S. Hershey Medical Center | Chronic Cutaneous Lupus Erythematosus, Gastric Cancer, Gastroesophageal Junction Cancer | 4 |
| Hershey Medical Center Pennsylvania State University | Cystic Fibrosis, Cystic Fibrosis (CF), Exocrine Pancreatic Insufficiency (EPI) | 3 |
| Penn State University | Ards, Blood Pressure, Blood Pressure, High | 3 |
| The Pennsylvania State University | Antibiotics, Hypersensitivity Pneumonitis, Interstitial Lung Disease | 3 |
| ADARx Clinical Site | HAE, Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2 | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Penn State Health Dept of Psychiatry | ADHD, ADHD - Attention Deficit Disorder With Hyperactivity, Aggression Childhood | 2 |
| Penn State Health Medical Group - Psychiatry and Behavioral Health | Anxiety, Attention-Deficit/Hyperactivity Disorder, Chronic Stress | 2 |
| Penn State Health Milton S. Hershey Medical Center (Hershey) | Hematologic Tests | 2 |
| Penn State Health, Milton S. Hershey Medical Center | Deep Venous Thromboses, Hepatitis | 2 |
| Penn State Hershey Children's Hospital | Anesthesia, Children, Deep Venous Thrombosis | 2 |
| Penn State Milton S. Hershey Medical Center / Penn State College of Medicine | Child Abuse, Child Maltreatment, Child Neglect | 2 |
| Penn State Health - Milton S. Hershey Medical Center | Acute Respiratory Distress Syndrome, Infections | 1 |
| 905 W Govener Rd | Anorexia Nervosa, Eating Disorders | 1 |
| Children's Hospital - Penn State Hershey | Failed or Difficult Intubation, Sequela, Intubation Complication, Intubation; Difficult | 1 |
| Exelixis Clinical | Clear Cell Renal Cell Carcinoma (ccRCC), Colorectal Cancer (CRC), Head and Neck Squamous Cell Carcinoma (HNSCC) | 1 |
| Hershey Medical Center | Colonic Neoplasms | 1 |
| Hershey Outpatient Surgery Center | Lumbar Spinal Stenosis | 1 |
| Ionis Investigative Site | Hereditary Angioedema (HAE) | 1 |
| Jessyka Lighthall | Pain Management, Rhinoplasty | 1 |
| Local Institution - 0045 | Colitis, Ulcerative | 1 |
| Local Institution - 0376 | Carcinoma, Non-Small-Cell Lung | 1 |
| Local Institution - 2114 | Locally Advanced Solid Tumors, Lymphoma, Metastatic Solid Tumors | 1 |
| Milton S Hershey Medical Center | Lumbar Spinal Stenosis | 1 |
| Milton S. Hershey Medical Center | Pennsylvania State University_Hershey | Muscular Atrophy, Spinal | 1 |
| Penn Hershey Medical Center | Glycogen Storage Disease Type II, Pompe Disease | 1 |
| Penn State | Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands | 1 |
| Penn State - Hershey Medical Center | Systemic Lupus Erythematosus | 1 |
| Penn State College of Medicine, Penn State Milton S. Hershey Medical Center | Obstructive Sleep Apnea | 1 |
| Penn State Health (Milton S. Hershey Medical Center) | Ileal Pouch | 1 |
| Penn State Health - Hershey Medical Center | Limit Emergence Phenomena After General Anesthesia | 1 |
| Penn State Health / Penn State Milton S. Hershey Medical Center | Infusion Reactions | 1 |
| Penn State Health Children's Hospital | Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation | 1 |
| Penn State Health Hershey & Berks | Coronary Artery Disease | 1 |
| Penn State Health Hershey Medical Center | CTCL, CTCL/ Mycosis Fungoides, Cutaneous T Cell Lymphoma | 1 |
| Penn State Health Milton S Hershey Medical Center | Neonatal Hypoglycemia | 1 |
Active & Upcoming Studies in Hershey (2026)
Recruiting trials in Hershey grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (99 active studies)
- Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma · Phase 2 · Milton S. Hershey Medical Center
- Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas · Phase 1, Phase 2 · Milton S. Hershey Medical Center
Cardiovascular (16 active studies)
- The WiSE®-UP Registry (The WiSE System Utilization & Performance Registry) · EBR Systems, Inc.
- SSVC-CI During CABG · Milton S. Hershey Medical Center
Neurology & pain (9 active studies)
- Feasibility of a Mindfulness Intervention for Endometriosis Surgery · Milton S. Hershey Medical Center
- Efficacy of Liposomal Bupivacaine Post Septorhinoplasty · Phase 3 · Jessyka Lighthall
Pediatric (8 active studies)
- Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · Weill Medical College of Cornell University
- Optimizing Tracheal Intubation Outcomes and Neonatal Safety · Children's Hospital of Philadelphia
Mental health & behavior (7 active studies)
- Impact of Electronic Cigarette Temperature and Solvent on Biomarkers · Milton S. Hershey Medical Center
- AYA-PeerConnect: A Communication Coaching Intervention for Adolescent/Young Adult Cancer Survivors (AYACS) · Milton S. Hershey Medical Center
Diabetes & metabolic (5 active studies)
- Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension · EARLY_Phase 1 · Milton S. Hershey Medical Center
- A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH · Phase 3 · Akero Therapeutics, Inc
Vaccines (2 active studies)
- Outpatient Treatment With Anti-Coronavirus Immunoglobulin · Phase 3 · University of Minnesota
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) · Duke University
Eye & vision (1 active study)
- Evaluation of a Monofocal Intraocular Lens · Phase 4 · Carl Zeiss Meditec AG
Common conditions studied in Hershey
- Neuroblastoma (8 active studies). Recruiting Neuroblastoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Myeloid Leukemia (7 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Breast Cancer (7 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Heart Failure (7 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Hereditary Angioedema (HAE) (5 active studies). Recruiting Hereditary Angioedema (HAE) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Prostate Cancer (5 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
Leading research sponsors in Hershey
- Milton S. Hershey Medical Center
- National Cancer Institute (NCI)
- NRG Oncology
- Children's Oncology Group
- AstraZeneca
Local regulations and guidelines
Clinical trials in Pennsylvania are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Pennsylvania research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Hershey. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Hershey
Hipa.ai aggregates every recruiting study in Hershey from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Hershey?
There are approximately 292 recruiting clinical trials in Hershey, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Hershey pay participants?
Most recruiting trials in Hershey compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Hershey?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Hershey?
The most common conditions under active study in Hershey include Neuroblastoma (8), Acute Myeloid Leukemia (7), Breast Cancer (7), Heart Failure (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Hershey?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Hershey on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Hershey?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Hershey?
Recruiting research sites in Hershey include Penn State Milton S Hershey Medical Center, Penn State Milton S. Hershey Medical Center, Penn State Children's Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Hershey right now?
The largest active categories in Hershey are Cancer & tumors (99), Cardiovascular (16), Neurology & pain (9). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.