GI oncology Clinical Trials in Houston, TX
As of September 2026, 146 paid clinical trials are recruiting for GI oncology in Houston, Texas. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Houston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors
148 clinical trials for GI oncology
·Clear filters·A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors
A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
A Study of PHST001 in Advanced Solid Tumors
A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
A Study of PHN-012 in Patients With Advanced Solid Tumors
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
Top Research Study Locations in Houston
Researchers run research studies in Houston, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| MD Anderson Cancer Center | Colorectal Cancer, Breast Cancer, Ovarian Cancer | 407 |
| M D Anderson Cancer Center | Hematopoietic and Lymphoid Cell Neoplasm, Acute Myeloid Leukemia, Malignant Solid Neoplasm | 252 |
| Baylor College of Medicine | Epilepsy, Heart Failure, Anxiety Disorders | 191 |
| The University of Texas Health Science Center at Houston | Cluster Headache, HIV Infections, Systemic Sclerosis | 183 |
| The University of Texas MD Anderson Cancer Center | Advanced Solid Tumor, Breast Cancer, Colorectal Cancer | 132 |
| Houston Methodist Hospital | Acute Respiratory Distress Syndrome, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 130 |
| Texas Children's Hospital | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, WHO Grade III Glioma | 111 |
| The University of Texas M. D. Anderson Cancer Center | Cancer, Breast Cancer, Prostate Cancer | 86 |
| University of Texas MD Anderson Cancer Center | Breast Cancer, Non-small Cell Lung Cancer, Chronic Lymphocytic Leukemia | 86 |
| UT MD Anderson Cancer Center | Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm | 71 |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 55 |
| MD Anderson | Myelodysplastic Syndromes, Myelofibrosis, Acute Myeloid Leukemia | 38 |
| Houston Methodist | Heart Failure, Cardiovascular Diseases, Heart Valve Diseases | 32 |
| Michael E. DeBakey VA Medical Center, Houston, TX | Spinal Cord Injury, Metastatic Prostate Cancer, Stress Disorders, Post-Traumatic | 31 |
| University of Texas Health Science Center at Houston | Infant, Small for Gestational Age, Infant, Low Birth Weight, Infant, Newborn | 28 |
| UT MD Anderson | Breast Cancer, AML, Acute Myeloid Leukemia | 26 |
| Ben Taub General Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 25 |
| Houston Methodist Research Institute | Hepatocellular Carcinoma, AAA, AAA - Abdominal Aortic Aneurysm | 23 |
| GSK Investigational Site | Chickenpox, HIV Infections, Gastrointestinal Neoplasms | 21 |
| The University of Texas M.D. Anderson Cancer Center | Advanced Breast Cancer, Breast Cancer, Metastatic Breast Cancer | 17 |
| Houston Methodist West Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, AL Amyloidosis | 16 |
| UTHealth Houston | Acute Suicidal Depression (ASD), Charcot-Marie-Tooth Disease Type 2D, Emergency Department Visits | 16 |
| Michael E. DeBakey VA Medical Center | Gulf War Syndrome, Adult Growth Hormone Deficiency, Alzheimer Disease | 14 |
| Memorial Hermann Texas Medical Center | Acute Kidney Injury, Ischemic Stroke, Ovarian Carcinoma | 14 |
| Oncology Consultants | Breast Cancer, Esophageal Cancer, Advanced Cancer | 14 |
Active & Upcoming Studies in Houston (2026)
Recruiting trials in Houston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (1,171 active studies)
- A Phase 1 Open-Label, Dose-Ranging Safety and Pharmacokinetics Study of Oral Cladribine in Patients With Acute Myeloid Leukemia (AML) · Phase 1, Phase 2 · M.D. Anderson Cancer Center
- Randomized Phase 2 Study Of Epcoritamab Vs Watch And Wait InPatients With Previously Untreated Low Tumor Burden FollicularLymphoma · Phase 2 · M.D. Anderson Cancer Center
Neurology & pain (140 active studies)
- Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke · EARLY_Phase 1 · University of Houston
- Prospective Randomized Study of TPS + CBT VS TPS Alone: Readmission, Opioid Use, and Chronic Pain · M.D. Anderson Cancer Center
Diabetes & metabolic (105 active studies)
- Benefits of Insoles With Real-Time Alert and Foot Self-Care Education · Texas Woman's University
- Continued Access to the Endogenex System for Participants in the ReCET Pivotal Study · Endogenex, Inc.
Cardiovascular (103 active studies)
- HiCM-188 Cell Therapy in Adults With Advanced Heart Failure Undergoing Heart Bypass Surgery · Phase 1, Phase 2 · HELP Therapeutics Co., Ltd.
- A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event · Phase 2 · Eli Lilly and Company
Mental health & behavior (80 active studies)
- ACT for Veterans With IBD and Mental Health Challenges · VA Office of Research and Development
- Pilot Randomized Trial of BA-GSH in VA PC-MHI · VA Office of Research and Development
Pediatric (45 active studies)
- Food is Medicine in Survivorship: Examining the Feasibility and Impact of a Scalable Food Delivery and Culinary Medicine Program (FoodiiS) Among Pediatric Cancer Survivors and Their Families · M.D. Anderson Cancer Center
- Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements · Kenneth Moise MD
HIV / STI (34 active studies)
- Improving HIV Prevention and Substance Use Post-Sexual Assault Services · The University of Texas Health Science Center, Houston
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (26 active studies)
- A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 Vaccine · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
Eye & vision (24 active studies)
- Treating Contact Lens Discomfort With Varenicline Solution Nasal Spray 0.03mg · Ocular Aesthetics, LLC dba Ocular Clinical Trials
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
Common conditions studied in Houston
- Breast Cancer (76 active studies)
- Acute Myeloid Leukemia (52 active studies)
- Advanced Solid Tumor (52 active studies)
- Colorectal Cancer (46 active studies)
- Ovarian Cancer (46 active studies)
- Prostate Cancer (43 active studies)
Leading research sponsors in Houston
- M.D. Anderson Cancer Center
- The University of Texas Health Science Center, Houston
- Baylor College of Medicine
- AstraZeneca
- The Methodist Hospital Research Institute
Frequently asked questions
How many paid clinical trials are currently recruiting in Houston?
There are approximately 3,045 recruiting clinical trials in Houston, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Houston pay participants?
Most recruiting trials in Houston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Houston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Houston?
The most common conditions under active study in Houston include Breast Cancer (76), Acute Myeloid Leukemia (52), Advanced Solid Tumor (52), Colorectal Cancer (46), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Houston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Houston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Houston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Houston?
Recruiting research sites in Houston include MD Anderson Cancer Center, M D Anderson Cancer Center, Baylor College of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Houston right now?
The largest active categories in Houston are Cancer & tumors (1,171), Neurology & pain (140), Diabetes & metabolic (105). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.