Paid Clinical Trials in Mechanicsburg, PA
As of August 2026, 41 paid clinical trials are recruiting in Mechanicsburg, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Mechanicsburg offers studies at sites including UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion for conditions such as Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma, Recurrent Endometrial Carcinoma, Anatomic Stage I Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Mechanicsburg
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·Clear filters·Top Research Study Locations in Mechanicsburg
Researchers run research studies in Mechanicsburg, PA at 8 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion | Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma, Recurrent Endometrial Carcinoma | 31 |
| UPMC Pinnacle | Aortic Stenosis, Coronary Arterial Disease (CAD), Coronary Artery Disease | 3 |
| Pinnacle Health System | Aortic Valve Disease, Aortic Valve Stenosis, Heart Disease Structural Disorder | 1 |
| UPMC | PAD, Peripheral Artery Calcification, Peripheral Artery Disease | 1 |
| UPMC Harrisburg | Atrial Fibrillation, Stroke | 1 |
| UPMC Hillman Cancer Center - Pinnacle (Ortenzio) | Colorectal Neoplasms | 1 |
| UPMC Pinnacle Hospitals | Cardiovascular Diseases, Functional Mitral Regurgitation, Heart Diseases | 1 |
| University of Pittsburgh Medical Center | Cardiovascular Diseases, Heart Failure, Heart Failure With Mid Range Ejection Fraction | 1 |
Active & Upcoming Studies in Mechanicsburg (2026)
Recruiting trials in Mechanicsburg grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (30 active studies)
- Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer · Phase 3 · National Cancer Institute (NCI)
- Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer · Phase 3 · Canadian Cancer Trials Group
Cardiovascular (7 active studies)
- A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease · Pulnovo Medical, Inc.
- AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions · Boston Scientific Corporation
Mental health & behavior (1 active study)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Neurology & pain (1 active study)
- The CONFORM Pivotal Trial · Conformal Medical, Inc
Common conditions studied in Mechanicsburg
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Head and Neck Squamous Cell Carcinoma (3 active studies)
- Recurrent Endometrial Carcinoma (3 active studies)
- Anatomic Stage I Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage III Breast Cancer AJCC v8 (2 active studies)
- Breast Cancer (2 active studies)
Leading research sponsors in Mechanicsburg
- National Cancer Institute (NCI)
- NRG Oncology
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- ECOG-ACRIN Cancer Research Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Mechanicsburg?
There are approximately 41 recruiting clinical trials in Mechanicsburg, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Mechanicsburg pay participants?
Most recruiting trials in Mechanicsburg compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Mechanicsburg?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Mechanicsburg?
The most common conditions under active study in Mechanicsburg include Anatomic Stage II Breast Cancer AJCC v8 (3), Head and Neck Squamous Cell Carcinoma (3), Recurrent Endometrial Carcinoma (3), Anatomic Stage I Breast Cancer AJCC v8 (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Mechanicsburg?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Mechanicsburg on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Mechanicsburg?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Mechanicsburg?
Recruiting research sites in Mechanicsburg include UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, UPMC Pinnacle, Pinnacle Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Mechanicsburg right now?
The largest active categories in Mechanicsburg are Cancer & tumors (30), Cardiovascular (7), Mental health & behavior (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.