MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
for Lumbar Spinal Stenosis
Sites in Normal, Bloomington +2367 more locations
Sponsor: Stryker Instruments
Sex: All·Age: 18+
Code: NCT03072927·Recruiting·Listed Mar 2017
Clinical Trials at Carle BroMenn Medical Center
As of August 2026, 40 paid clinical trials are recruiting at Carle BroMenn Medical Center, located at 1304 FRANKLIN AVE, NORMAL, IL 61761-3558, phone (309) 454-1400 in Normal, Illinois. Active studies at this site cover conditions such as Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 and Recurrent Endometrial Carcinoma. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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40 clinical trials at Carle BroMenn Medical Center
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Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
for Lung Non-Small Cell Carcinoma
Drug: Atezolizumab
Sites in Normal, Bloomington +57 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07388524·Phase 3·Recruiting·Listed Feb 2026
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
for Chronic Lymphocytic Leukemia
Drug: Sonrotoclax
Sites in Normal, Bloomington +179 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 65+
Code: NCT07321652·Phase 3·Recruiting·Listed Jan 2026
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
for Ampulla of Vater Carcinoma
Sites in Normal, Bloomington +347 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07283939·Recruiting·Listed Dec 2025
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
for Advanced Endometrial Carcinoma
Drug: Bevacizumab
Sites in Normal, Peoria +254 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT07198074·Phase 3·Recruiting·Listed Sep 2025
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Normal, Bloomington +1098 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Family Communications After Genetic Testing
for Colon Adenocarcinoma
Sites in Normal, Bloomington +288 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07143487·Recruiting·Listed Aug 2025
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Normal, Bloomington +777 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Normal, Bloomington +591 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
Sites in Normal, Bloomington +616 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting·Listed Apr 2022
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Normal, Bloomington +482 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
for Miscellaneous Neoplasm, Nos
Sites in Normal, Bloomington +276 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07091617·Recruiting·Listed Jul 2025
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
for Fallopian Tube Endometrioid Adenocarcinoma
Drug: Bevacizumab
Sites in Normal, Bloomington +653 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024
Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects
for Malignancy
Sites in Normal, Washington +392 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: All ages
Code: NCT04242095·Recruiting·Listed Jan 2020
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Normal, Bloomington +532 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
for Malignant Solid Neoplasm
Sites in Normal, Bloomington +353 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT06295367·Recruiting·Listed Mar 2024
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
for Ovarian Carcinoma
Sites in Normal, Bloomington +479 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 35 - 50
Code: NCT04251052·Recruiting·Listed Jan 2020
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
for Advanced Malignant Solid Neoplasm
Sites in Normal, Bloomington +429 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: All ages
Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
for Clinical Stage III Cutaneous Melanoma AJCC v8
Drug: Cabozantinib
Sites in Normal, Bloomington +207 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05136196·Phase 2·Recruiting·Listed Nov 2021
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program
for Cigarette Smoking-Related Carcinoma
Sites in Normal, Bloomington +205 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05008848·Phase 3·Recruiting·Listed Aug 2021
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
for Hematopoietic and Lymphatic System Neoplasm
Sites in Normal, Springfield +189 more locations
Sponsor: Children's Oncology Group
Sex: Female·Age: Up to 39
Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
for Locally Advanced Urothelial Carcinoma
Sites in Normal, Decatur +157 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06524544·Phase 3·Recruiting·Listed Jul 2024
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
for Castration-Sensitive Prostate Carcinoma
Drug: Apalutamide
Sites in Normal, Bloomington +193 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: Male·Age: 18+
Code: NCT06931340·Phase 3·Recruiting·Listed Apr 2025
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial
for Non-Muscle Invasive Bladder Urothelial Carcinoma
Sites in Normal, Decatur +129 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06770582·Phase 2·Recruiting·Listed Jan 2025
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
for Malignant Female Reproductive System Neoplasm
Sites in Normal, Decatur +176 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06126276·Phase 2·Recruiting·Listed Nov 2023
Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer
for Locally Advanced Adrenal Cortical Carcinoma
Drug: Cabozantinib
Sites in Normal, Urbana +78 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 12+
Code: NCT06900595·Phase 2·Recruiting·Listed Mar 2025
Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
for Endometrial Adenocarcinoma
Drug: Ipilimumab
Sites in Normal, Urbana +123 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT05112601·Phase 2·Recruiting·Listed Nov 2021
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment
for Metastatic Head and Neck Squamous Cell Carcinoma
Sites in Normal, Peoria +189 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06589804·Phase 3·Recruiting·Listed Sep 2024
Project: Every Child for Younger Patients With Cancer
for Adrenal Gland Pheochromocytoma
Sites in Normal, Peoria +225 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 25
Code: NCT02402244·Recruiting·Listed Mar 2015
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers
for Pancreatic Neoplasm
Sites in Normal, Bloomington +333 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 50 - 75
Code: NCT04239573·Recruiting·Listed Jan 2020
Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System
for Locally Recurrent Skin Squamous Cell Carcinoma
Drug: Amivantamab
Sites in Normal, Urbana +49 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07042295·Phase 2·Recruiting·Listed Jun 2025
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
for Locally Advanced Pancreatic Adenocarcinoma
Sites in Normal, Bloomington +270 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT06998940·Phase 3·Recruiting·Listed May 2025
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
for Malignant Solid Neoplasm
Sites in Normal, Bloomington +586 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT04871542·Recruiting·Listed May 2021
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
for Stage I Breast Cancer
Sites in Normal, Bloomington +705 more locations
Sponsor: NRG Oncology
Sex: All·Age: 50 - 70
Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
for Recurrent Lung Non-Small Cell Carcinoma
Drug: Cemiplimab
Sites in Normal, Bloomington +379 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024
The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials
for Cancer
Sites in Normal, Bloomington +65 more locations
Sponsor: Eastern Cooperative Oncology Group
Sex: All·Age: 18+
Code: NCT06756607·Recruiting·Listed Jan 2025
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
for Colorectal Cancer Stage II
Sites in Normal, Bloomington +373 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07018869·Phase 3·Recruiting·Listed Jun 2025
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Normal, Bloomington +913 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
for Advanced Colorectal Carcinoma
Sites in Normal, Bloomington +194 more locations
Sponsor: University of Rochester
Sex: All·Age: 18+
Code: NCT06073431·Recruiting·Listed Oct 2023
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
for Colorectal Cancer
Sites in Normal, Bloomington +140 more locations
Sponsor: Wake Forest University Health Sciences
Sex: All·Age: 60+
Code: NCT03998202·Recruiting·Listed Jun 2019
Common conditions studied in Normal
- Malignant Solid Neoplasm (6 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Recurrent Endometrial Carcinoma (3 active studies)
- Anatomic Stage I Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage III Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (2 active studies)
Leading research sponsors in Normal
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- NRG Oncology
- SWOG Cancer Research Network
- ECOG-ACRIN Cancer Research Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Normal?
There are approximately 53 recruiting clinical trials in Normal, Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Normal pay participants?
Most recruiting trials in Normal compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Normal?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Normal?
The most common conditions under active study in Normal include Malignant Solid Neoplasm (6), Anatomic Stage II Breast Cancer AJCC v8 (4), Recurrent Endometrial Carcinoma (3), Anatomic Stage I Breast Cancer AJCC v8 (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Normal?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Normal on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Normal?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Normal?
Recruiting research sites in Normal include Carle Cancer Institute Normal, Carle BroMenn Medical Center, Sneeze Wheeze & Itch Associates, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Normal right now?
The largest active categories in Normal are Cancer & tumors (37), Mental health & behavior (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Carle BroMenn Medical Center?
Carle BroMenn Medical Center is located at 1304 FRANKLIN AVE, NORMAL, IL 61761-3558. Use the Google Maps link in the intro above to get directions.
How do I contact Carle BroMenn Medical Center?
You can reach Carle BroMenn Medical Center by phone at (309) 454-1400. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
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