BOdygUardian MOnitoriNg for ReCurrencE of AF
for Atrial Fibrillation (AF)
Sites in Pittsburgh +2 more locations
Sponsor: Heart Rhythm Clinical and Research Solutions, LLC
Sex: All·Age: 18+
Code: NCT07671677·Not Yet Recruiting·Listed Jun 26, 2026
Clinical Trials at Allegheny General Hospital
As of August 2026, 63 paid clinical trials are recruiting at Allegheny General Hospital, located at 320 E NORTH AVE, PITTSBURGH, PA 15212-4756, phone (412) 359-3131 in Pittsburgh, Pennsylvania. Active studies at this site cover conditions such as Breast Cancer, Melanoma and Stroke. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Filter results
Newly added in Pittsburgh
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
64 clinical trials at Allegheny General Hospital
·Clear filters·An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
for Cardiovascular Disease and Lipoprotein(a)
Drug: Pelacarsen
Sites in Pittsburgh, Lancaster +110 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18 - 100
Code: NCT07517263·Phase 3·Recruiting·Listed Apr 2026
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
for Parkinson's Disease
Drug: Prasinezumab
Sites in Pittsburgh, Philadelphia +48 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 50 - 85
Code: NCT07174310·Phase 3·Recruiting·Listed Sep 2025
Assessment of CCM in HF With Higher Ejection Fraction
for Heart Failure
Sites in Pittsburgh, Hershey +74 more locations
Sponsor: Impulse Dynamics
Sex: All·Age: 18+
Code: NCT05064709·Recruiting·Listed Oct 2021
FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3
for Urinary Bladder Neoplasms
Sites in Pittsburgh, Lancaster +39 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT05614739·Phase 1·Recruiting·Listed Nov 2022
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
for Refractory Angina
Sites in Pittsburgh +65 more locations
Sponsor: Shockwave Medical, Inc.
Sex: All·Age: 18+
Code: NCT05102019·Recruiting·Listed Nov 2021
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
for Advanced Non-small Cell Lung Cancer, HER2 Mutation
Sites in Pittsburgh +15 more locations
Sponsor: Bayer
Sex: All·Age: 18+
Code: NCT06452277·Phase 3·Recruiting·Listed Jun 2024
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
for Aortic Valve Insufficiency
Sites in Pittsburgh +31 more locations
Sponsor: Edwards Lifesciences
Sex: All·Age: All ages
Code: NCT05172973·Recruiting·Listed Dec 2021
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
for Heart Failure
Sites in Pittsburgh, Hershey +55 more locations
Sponsor: Abbott Medical Devices
Sex: All·Age: 18+
Code: NCT06526195·Recruiting·Listed Jul 2024
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
for Aortic Stenosis
Sites in Pittsburgh, Mechanicsburg +69 more locations
Sponsor: Medtronic Cardiovascular
Sex: All·Age: 18 - 105
Code: NCT06777368·Recruiting·Listed Jan 2025
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Sites in Pittsburgh, Philadelphia +35 more locations
Sponsor: Intellia Therapeutics
Sex: All·Age: 18 - 90
Code: NCT06128629·Phase 3·Recruiting·Listed Nov 2023
PARTNER 3 Trial - Aortic Valve-in-Valve
for Aortic Stenosis
Sites in Pittsburgh, Wynnewood +27 more locations
Sponsor: Edwards Lifesciences
Sex: All·Age: All ages
Code: NCT03003299·Recruiting·Listed Dec 2016
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
for Atrial Fibrillation (AF)
Sites in Pittsburgh, Philadelphia +20 more locations
Sponsor: Medtronic Cardiac Ablation Solutions
Sex: All·Age: 18+
Code: NCT07298473·Recruiting·Listed Dec 2025
Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA
for Aortic Arch Aneurysm
Sites in Pittsburgh, Philadelphia +19 more locations
Sponsor: Artivion Inc.
Sex: All·Age: 18 - 80
Code: NCT07089576·Recruiting·Listed Jul 2025
The ArtixASCEND Study
for Acute Lower Limb Arterial Occlusion
Sites in Pittsburgh +19 more locations
Sponsor: Inari Medical
Sex: All·Age: 18+
Code: NCT07135895·Recruiting·Listed Aug 2025
Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain
for Chronic Low-back Pain
Sites in Pittsburgh +16 more locations
Sponsor: Boston Scientific Corporation
Sex: All·Age: 18+
Code: NCT06827262·Recruiting·Listed Feb 2025
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
for Healthy Volunteers, Pulmonary Arterial Hypertension
Sites in Pittsburgh +19 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18 - 100·Accepts healthy volunteers
Code: NCT06649110·Phase 1, Phase 2·Recruiting·Listed Oct 2024
The PERSEVERE Study
for Pulmonary Embolism
Sites in Pittsburgh, Philadelphia +13 more locations
Sponsor: Inari Medical
Sex: All·Age: 18+
Code: NCT06588634·Recruiting·Listed Sep 2024
A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)
for Extensive Stage Small Cell Lung Cancer
Drug: Tarlatamab
Sites in Pittsburgh, Philadelphia +11 more locations
Sponsor: Amgen
Sex: All·Age: 18 - 90
Code: NCT07037758·Phase 1·Recruiting·Listed Jun 2025
Vivistim Registry for Paired VNS Therapy (GRASP)
for Upper Extremity Problem
Sites in Pittsburgh, Scranton +13 more locations
Sponsor: MicroTransponder Inc.
Sex: All·Age: 22+
Code: NCT05301140·Recruiting·Listed Mar 2022
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
for Emphysema, Pulmonary
Sites in Pittsburgh, Philadelphia +14 more locations
Sponsor: Pulmonx Corporation
Sex: All·Age: 40 - 80
Code: NCT06035120·Recruiting·Listed Sep 2023
Medtronic Terminate AF Study
for Persistent Atrial Fibrillation
Sites in Pittsburgh +6 more locations
Sponsor: Medtronic Cardiac Surgery
Sex: All·Age: 18+
Code: NCT03546374·Recruiting·Listed Jun 2018
Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT
for Thrombosis, Deep Vein
Sites in Pittsburgh +12 more locations
Sponsor: Mercator MedSystems, Inc.
Sex: All·Age: 18 - 89
Code: NCT04862468·Phase 2·Recruiting·Listed Apr 2021
Intervascular Post-Market Clinical Follow-Up (PMCF) Registry
for Carotid Artery Diseases
Sites in Pittsburgh & Hershey
Sponsor: Intervascular
Sex: All·Age: 18+
Code: NCT07322913·Recruiting·Listed Jan 2026
Deep Brain Stimulation (DBS) Retrospective Outcomes Study
for Parkinson Disease
Sites in Pittsburgh +6 more locations
Sponsor: Boston Scientific Corporation
Sex: All·Age: All ages
Code: NCT03664609·Recruiting·Listed Sep 2018
Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer
for Locally Advanced Pancreatic Adenocarcinoma
Sites in Pittsburgh, Philadelphia +5 more locations
Sponsor: EXACT Therapeutics AS
Sex: All·Age: 18+
Code: NCT06850623·Phase 2·Recruiting·Listed Feb 2025
Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer
for Astrocytoma, IDH-Mutant, Grade 3
Drug: Vorasidenib
Sites in Pittsburgh, Monroeville +95 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 12+
Code: NCT07215910·Phase 3·Recruiting·Listed Oct 2025
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Pittsburgh, Monroeville +1098 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Pittsburgh, McKeesport +913 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Pittsburgh, Monroeville +777 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Pittsburgh, McKeesport +591 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Pittsburgh, Lewistown +482 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
for Bladder Adenocarcinoma
Drug: Cabozantinib
Sites in Pittsburgh, Monroeville +221 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03866382·Phase 2·Recruiting·Listed Mar 2019
Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer
for Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Sites in Pittsburgh, Monroeville +103 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07195734·Phase 2·Recruiting·Listed Sep 2025
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
for Locally Advanced Cervical Adenocarcinoma
Sites in Pittsburgh, Monroeville +303 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Pittsburgh, Monroeville +533 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
for Extensive Stage Lung Small Cell Carcinoma
Drug: Atezolizumab
Sites in Pittsburgh, Monroeville +268 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04402788·Phase 2, Phase 3·Recruiting·Listed May 2020
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma
Sites in Pittsburgh, Monroeville +314 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06958328·Phase 3·Recruiting·Listed May 2025
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
for Ovarian Carcinoma
Sites in Pittsburgh, Monroeville +479 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 35 - 50
Code: NCT04251052·Recruiting·Listed Jan 2020
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
for Metastatic Renal Cell Carcinoma
Sites in Pittsburgh, Monroeville +278 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05327686·Phase 2·Recruiting·Listed Apr 2022
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
for Castration-Sensitive Prostate Carcinoma
Drug: Apalutamide
Sites in Pittsburgh, Monroeville +193 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: Male·Age: 18+
Code: NCT06931340·Phase 3·Recruiting·Listed Apr 2025
Common conditions studied in Pittsburgh
- Breast Cancer (25 active studies)
- Cancer (19 active studies)
- Melanoma (18 active studies)
- Stroke (17 active studies)
- Endometrial Cancer (16 active studies)
- Ovarian Cancer (16 active studies)
Leading research sponsors in Pittsburgh
- University of Pittsburgh
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Pittsburgh?
There are approximately 1,247 recruiting clinical trials in Pittsburgh, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Pittsburgh pay participants?
Most recruiting trials in Pittsburgh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Pittsburgh?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Pittsburgh?
The most common conditions under active study in Pittsburgh include Breast Cancer (25), Cancer (19), Melanoma (18), Stroke (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Pittsburgh?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Pittsburgh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Pittsburgh?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Pittsburgh?
Recruiting research sites in Pittsburgh include University of Pittsburgh, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Pittsburgh right now?
The largest active categories in Pittsburgh are Cancer & tumors (402), Neurology & pain (84), Cardiovascular (71). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Allegheny General Hospital?
Allegheny General Hospital is located at 320 E NORTH AVE, PITTSBURGH, PA 15212-4756. Use the Google Maps link in the intro above to get directions.
How do I contact Allegheny General Hospital?
You can reach Allegheny General Hospital by phone at (412) 359-3131. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
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