Oncology Clinical Trials in San Antonio, TX
As of July 2026, 263 paid clinical trials are recruiting for Oncology in San Antonio, Texas. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
Newly added in San Antonio
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Phase 1/2 Study of UI-102 in Selected Advanced Cancers
Clinical Study of MK-4884 in Participants With Advanced or Metastatic Solid Tumors (MK-4884-001)
Study of GS-2426 in Participants With Advanced Solid Tumors
267 clinical trials for Oncology
·Clear filters·↓ Download CSVA Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer
ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors
About research studies in San Antonio
San Antonio has approximately 986 recruiting research studies across a wide range of therapeutic areas. Texas hosts major cancer and cardiovascular research centers including MD Anderson Cancer Center, Baylor College of Medicine, UT Southwestern Medical Center, and the Texas Medical Center — the largest medical complex in the world.
Top Research Study Locations in San Antonio
Researchers run research studies in San Antonio, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Texas Health Science Center at San Antonio | Cardiovascular Diseases, Type 2 Diabetes, Acute Myeloid Leukemia | 85 |
| NEXT Oncology | Advanced Solid Tumor, Advanced Solid Tumors, Colorectal Cancer | 56 |
| Children's Hospital of San Antonio | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 32 |
| Methodist Children's Hospital of South Texas | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 24 |
| START San Antonio | Advanced Solid Tumor, Breast Cancer, Colorectal Cancer | 22 |
| The University of Texas Health Science Center at San Antonio | Aging, Bladder Carcinoma, Blood Pressure | 21 |
| UT Health San Antonio | Focal Epilepsy, Colorectal Cancer, Pancreatic Cancer | 16 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Neoplasms, Gastrointestinal Neoplasms | 13 |
| Texas Dermatology and Laser Specialists | Eczema, Plaque Psoriasis, Alopecia | 13 |
| Texas Oncology - San Antonio | Colorectal Neoplasms, Pancreatic Ductal Adenocarcinoma, Acinar Cell Carcinoma | 12 |
| Brooke Army Medical Center | Carpal Tunnel Syndrome, Chronic Pain, Combat Casualty Care | 11 |
| American Research Corporation at the Texas Liver Institute | Healthy, Hepatic Impairment, Liver Cirrhosis | 10 |
| Southern Star Research Institute | Colitis, Ulcerative, Crohn Disease, Irritable Bowel Syndrome | 9 |
| University Hospital | Hemorrhage, Surgical, Tonsillar Bleeding, CMV | 9 |
| Endeavor Clinical Trials | Obesity, Overweight, Cardiovascular Diseases | 8 |
| NEXT San Antonio | Advanced Solid Tumors, Endometrial Cancer, Cervical Cancer | 8 |
| Southern Star Research Institute, LLC | Colitis, Ulcerative, Crohn Disease, Crohn's Disease | 8 |
| South Texas Accelerated Research Therapeutics (START) | Advanced Solid Tumors, Head and Neck Squamous Cell Carcinoma, Non-small Cell Lung Cancer | 7 |
| Texas Transplant Institute | Large B-cell Lymphoma, Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma | 7 |
| Urology San Antonio | Prostate Cancer, FGFR Gene Alterations, FGFR Gene Amplification | 7 |
| IMA Clinical Research San Antonio | Obesity, Overweight, Cardiovascular Diseases | 6 |
| Methodist Hospital | AMI Cardiogenic Shock, Acute Kidney Injury, Aortic Stenosis | 6 |
| START - San Antonio | Advanced Solid Tumors, Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC), Advanced or Metastatic ER+ HER2- Breast Cancer (mBC) | 6 |
| South Texas Health Care System, San Antonio, TX | Adult Growth Hormone Deficiency, Alcohol Use Disorder (AUD), Chronic Low Back Pain | 6 |
| South Texas Veterans Health Care System | Hearing Disability, Mobility Disability, Anxiety | 6 |
Active & Upcoming Studies in San Antonio (2026)
Recruiting trials in San Antonio grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (303 active studies)
- Genetic Investigation of Cancer Predisposition · The University of Texas Health Science Center at San Antonio
- SCIPI Implementation and Evaluation: A Multi-site Proof-of-Concept Pilot Trial · The University of Texas Health Science Center at San Antonio
Diabetes & metabolic (85 active studies)
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
- Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Neurology & pain (47 active studies)
- SwallowFIT Study in Parkinson's Disease · The University of Texas Health Science Center at San Antonio
- DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea. · Phase 2 · Incannex Healthcare Ltd
Cardiovascular (33 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- PULSE - Patient Understanding and Learning Through Structured Education - Effectiveness and Implementation of Patient Education Videos in a New Pediatric Cardiology Clinic: A Stepped Wedge Cluster Randomized Trial · Driscoll Children's Hospital
Eye & vision (20 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
Mental health & behavior (16 active studies)
Pediatric (12 active studies)
- MiniMed Fit Payload Wear Pediatric Study · Medtronic MiniMed, Inc.
- PULSE - Patient Understanding and Learning Through Structured Education - Effectiveness and Implementation of Patient Education Videos in a New Pediatric Cardiology Clinic: A Stepped Wedge Cluster Randomized Trial · Driscoll Children's Hospital
HIV / STI (4 active studies)
- Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions · Phase 2 · AusperBio Therapeutics Inc.
- Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals · The University of Texas Health Science Center at San Antonio
Vaccines (3 active studies)
Common conditions studied in San Antonio
- Advanced Solid Tumor (39 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumors (30 active studies). Recruiting Advanced Solid Tumors studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Obesity (27 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Breast Cancer (26 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Ovarian Cancer (22 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Colorectal Cancer (21 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
Leading research sponsors in San Antonio
- The University of Texas Health Science Center at San Antonio
- Eli Lilly and Company
- AstraZeneca
- Bristol-Myers Squibb
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Texas are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials run in Texas must also comply with the Texas Medical Privacy Act (TMPA), which extends federal HIPAA protections to a broader range of entities handling participant data.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in San Antonio. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in San Antonio
Hipa.ai aggregates every recruiting study in San Antonio from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in San Antonio?
There are approximately 986 recruiting clinical trials in San Antonio, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Antonio pay participants?
Most recruiting trials in San Antonio compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Antonio?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Antonio?
The most common conditions under active study in San Antonio include Advanced Solid Tumor (39), Advanced Solid Tumors (30), Obesity (27), Breast Cancer (26), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Antonio?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Antonio on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Antonio?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Antonio?
Recruiting research sites in San Antonio include University of Texas Health Science Center at San Antonio, NEXT Oncology, Children's Hospital of San Antonio, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Antonio right now?
The largest active categories in San Antonio are Cancer & tumors (303), Diabetes & metabolic (85), Neurology & pain (47). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.