Oncology Clinical Trials in San Antonio, TX
As of September 2026, 257 paid clinical trials are recruiting for Oncology in San Antonio, Texas. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in San Antonio
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors
A Study to Evaluate the Safety and Antitumor Activity of GS-1206 in Adults With Solid Tumors
260 clinical trials for Oncology
·Clear filters·A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study of ASP3082 in Adults With Advanced Solid Tumors
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
Top Research Study Locations in San Antonio
Researchers run research studies in San Antonio, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Texas Health Science Center at San Antonio | Cardiovascular Diseases, Type 2 Diabetes, Acute Myeloid Leukemia | 85 |
| NEXT Oncology | Advanced Solid Tumor, Advanced Solid Tumors, NSCLC | 56 |
| Children's Hospital of San Antonio | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 30 |
| START San Antonio | Advanced Solid Tumor, Advanced Solid Tumors, Breast Cancer | 24 |
| Methodist Children's Hospital of South Texas | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 23 |
| The University of Texas Health Science Center at San Antonio | Aging, Bladder Carcinoma, Blood Pressure | 21 |
| UT Health San Antonio | Focal Epilepsy, Colorectal Cancer, Pancreatic Cancer | 17 |
| Texas Dermatology and Laser Specialists | Atopic Dermatitis, Eczema, Plaque Psoriasis | 15 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Neoplasms, Asthma | 14 |
| Texas Oncology - San Antonio | Colorectal Neoplasms, Pancreatic Ductal Adenocarcinoma, Acinar Cell Carcinoma | 12 |
| Brooke Army Medical Center | Carpal Tunnel Syndrome, Chronic Pain, Combat Casualty Care | 12 |
| American Research Corporation at the Texas Liver Institute | Healthy, Hepatic Impairment, Liver Cirrhosis | 10 |
| Southern Star Research Institute | Colitis, Ulcerative, Crohn Disease, Irritable Bowel Syndrome | 9 |
| University Hospital | Hemorrhage, Surgical, Tonsillar Bleeding, CMV | 9 |
| Endeavor Clinical Trials | Obesity, Overweight, Cardiovascular Diseases | 8 |
| NEXT San Antonio | Advanced Solid Tumors, Endometrial Cancer, Cervical Cancer | 8 |
| Southern Star Research Institute, LLC | Colitis, Ulcerative, Crohn Disease, Crohn's Disease | 8 |
| South Texas Accelerated Research Therapeutics (START) | Head and Neck Squamous Cell Carcinoma, Non-small Cell Lung Cancer, Advanced Solid Tumor | 7 |
| Sun Research Institute | Pneumococcal Disease, Chronic Idiopathic Constipation (CIC), Hypertension (HTN) | 7 |
| Texas Transplant Institute | Large B-cell Lymphoma, Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma | 7 |
| University of Texas Health Science Center San Antonio | Intracerebral Hemorrhage, Advanced Breast Cancer, Alcohol Consumption | 7 |
| IMA Clinical Research San Antonio | Obesity, Overweight, Cardiovascular Diseases | 6 |
| Methodist Hospital | AMI Cardiogenic Shock, Acute Kidney Injury, Aortic Stenosis | 6 |
| Pinnacle Clinical Research - San Antonio | Hepatic Impairment, Liver Fibrosis, MASH - Metabolic Dysfunction-Associated Steatohepatitis | 6 |
| START - San Antonio | Advanced Solid Tumors, Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC), Advanced or Metastatic ER+ HER2- Breast Cancer (mBC) | 6 |
Active & Upcoming Studies in San Antonio (2026)
Recruiting trials in San Antonio grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (293 active studies)
- Genetic Investigation of Cancer Predisposition · The University of Texas Health Science Center at San Antonio
- SCIPI Implementation and Evaluation: A Multi-site Proof-of-Concept Pilot Trial · The University of Texas Health Science Center at San Antonio
Diabetes & metabolic (90 active studies)
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
Neurology & pain (44 active studies)
- Behavioral Resources and Awareness for Veterans With Episodic Migraine: Impact on Neurological Disability and Quality of Life- Pilot · Yale University
- SwallowFIT Study in Parkinson's Disease · The University of Texas Health Science Center at San Antonio
Cardiovascular (35 active studies)
- A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF · Phase 3 · AstraZeneca
- PULSE - Patient Understanding and Learning Through Structured Education - Effectiveness and Implementation of Patient Education Videos in a New Pediatric Cardiology Clinic · Driscoll Children's Hospital
Eye & vision (21 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
Mental health & behavior (14 active studies)
Pediatric (11 active studies)
- PULSE - Patient Understanding and Learning Through Structured Education - Effectiveness and Implementation of Patient Education Videos in a New Pediatric Cardiology Clinic · Driscoll Children's Hospital
- Neonatal Platelet Transfusion Threshold Trial · NICHD Neonatal Research Network
HIV / STI (4 active studies)
- Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions · Phase 2 · AusperBio Therapeutics Inc.
- Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals · The University of Texas Health Science Center at San Antonio
Vaccines (3 active studies)
Common conditions studied in San Antonio
- Advanced Solid Tumor (40 active studies)
- Advanced Solid Tumors (31 active studies)
- Obesity (31 active studies)
- Breast Cancer (26 active studies)
- Overweight (23 active studies)
- Ovarian Cancer (21 active studies)
Leading research sponsors in San Antonio
- The University of Texas Health Science Center at San Antonio
- Eli Lilly and Company
- AstraZeneca
- Pfizer
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in San Antonio?
There are approximately 991 recruiting clinical trials in San Antonio, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Antonio pay participants?
Most recruiting trials in San Antonio compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Antonio?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Antonio?
The most common conditions under active study in San Antonio include Advanced Solid Tumor (40), Advanced Solid Tumors (31), Obesity (31), Breast Cancer (26), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Antonio?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Antonio on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Antonio?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Antonio?
Recruiting research sites in San Antonio include University of Texas Health Science Center at San Antonio, NEXT Oncology, Children's Hospital of San Antonio, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Antonio right now?
The largest active categories in San Antonio are Cancer & tumors (293), Diabetes & metabolic (90), Neurology & pain (44). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.