Paid Clinical Trials in Southfield, MI
As of June 2026, 80 paid clinical trials are recruiting in Southfield, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Southfield offers studies at sites including Henry Ford Health Providence Southfield Hospital for conditions such as Breast Cancer, Obesity, Anatomic Stage II Breast Cancer AJCC v8, Degenerative Disc Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Southfield
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Southfield has approximately 80 recruiting research studies across a wide range of therapeutic areas. Michigan hosts University of Michigan Health, Henry Ford Health, and Corewell Health, running trials across oncology, neurology, and cardiology with a strong focus on precision medicine.
Top Research Study Locations in Southfield
Researchers run research studies in Southfield, MI at 35 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Henry Ford Health Providence Southfield Hospital | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Anatomic Stage I Breast Cancer AJCC v8 | 28 |
| Michigan Orthopaedic Surgeons | Degenerative Disc Disease, Disc Herniation, Sacroiliac Joint Dysfunction | 5 |
| Henry Ford Providence Hospital | Heart Failure, Hypertension, Cardiovascular Diseases | 4 |
| DM Clinical Research - Detroit | Clostridioides Difficile Associated Disease, Gout, Tophaceous Gout | 3 |
| Revive Research Institute | COPD, Chronic Obstructive Pulmonary Disease, Moderate to Severe Asthma | 3 |
| Revive Research Institute, Inc. | Clostridioides Difficile Associated Disease, Moderate to Severe Chronic Obstructive Pulmonary Disease, Obesity | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Great Lakes Research Institute | Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity, Overweight | 2 |
| Headlands Research - Detroit | Obesity, Overweight | 2 |
| Ascension Providence Hospital | Diastolic Heart Failure, Heart Failure, Heart Failure With Mid Range Ejection Fraction | 1 |
| Ascension Providence Hospital Southfield Cancer Center | Triple Negative Breast Cancer | 1 |
| Ascension Providence Hospitals - Southfield | Cardiotoxicity, HER2/Neu Positive, Metastatic Malignant Neoplasm in the Brain | 1 |
| Ascension St. Mary's Research Institute - Michigan | Acute Myocardial Infarction (AMI), Cardiovascular Risk | 1 |
| Clinical Trial Site | High Cardiovascular Risk, High Risk Cardiovascular Disease, Hypertension | 1 |
| Enveda Investigative Site | Asthma | 1 |
| GSK Investigational Site | Hypereosinophilic Syndrome | 1 |
| Great Lakes Research Inst. | Diabetes Mellitus, Type 2 | 1 |
| Great Lakes Surgical Center | Lumbar Spinal Stenosis | 1 |
| Henry Ford Health System | Heart Failure, Obesity | 1 |
| Henry Ford Providence | Refractory Angina | 1 |
| Henry Ford Providence Southfield CK Potluri Cancer Center | Multiple Myeloma | 1 |
| Henry Ford Providence Southfield Hospital | Atrial Fibrillation, Stroke | 1 |
| Invivyd Investigative Site | COVID-19 | 1 |
| Local Institution - 0071 | Multiple Sclerosis Spasticity | 1 |
| Michigan Orthopaedic Surgeons, PLLC | Arthroplasty Complications, Infection, Knee Disease | 1 |
| Michigan Orthopedic Surgeons | Degenerative Disc Disease | 1 |
| Providence - Providence Park Hospital | Breast Cancer | 1 |
| Providence Cancer Institute | Neoplasms | 1 |
| Revival Research Institute | Cardiovascular Disease | 1 |
| Revival Research Institute, LLC | Alzheimer Disease, Dementia, Plaque, Amyloid | 1 |
| Revive Research Institute - Southfield - 23999 Northwestern Hwy | Narcolepsy | 1 |
| Revive Research Institute, Inc | Chronic Obstructive Pulmonary Disease | 1 |
| Southfield, Michigan | Idiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 2 | 1 |
| Surgeons Choice Medical Center | Lumbar Spinal Stenosis | 1 |
| Takeda | Narcolepsy Type 1 (NT1), Narcolepsy With Cataplexy | 1 |
Active & Upcoming Studies in Southfield (2026)
Recruiting trials in Southfield grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (29 active studies)
- ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab · Phase 3 · Alliance for Clinical Trials in Oncology
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Diabetes & metabolic (9 active studies)
- A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes · Phase 3 · Novo Nordisk A/S
- A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight · Phase 2 · Eli Lilly and Company
Cardiovascular (8 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease · Phase 3 · Alnylam Pharmaceuticals
Neurology & pain (4 active studies)
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). · Phase 3 · Eli Lilly and Company
- A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight · Phase 3 · Eli Lilly and Company
Vaccines (1 active study)
- Study of VYD2311 for the Prevention of COVID-19 · Phase 3 · Invivyd, Inc.
Mental health & behavior (1 active study)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Common conditions studied in Southfield
- Breast Cancer (5 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Obesity (5 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Degenerative Disc Disease (4 active studies). Recruiting Degenerative Disc Disease studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Heart Failure (4 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Overweight (4 active studies). Recruiting Overweight studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Southfield
- National Cancer Institute (NCI)
- Eli Lilly and Company
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- NRG Oncology
Local regulations and guidelines
Clinical trials in Michigan are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Michigan research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Southfield. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Southfield
Hipa.ai aggregates every recruiting study in Southfield from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Southfield?
There are approximately 80 recruiting clinical trials in Southfield, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Southfield pay participants?
Most recruiting trials in Southfield compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Southfield?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Southfield?
The most common conditions under active study in Southfield include Breast Cancer (5), Obesity (5), Anatomic Stage II Breast Cancer AJCC v8 (4), Degenerative Disc Disease (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Southfield?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Southfield on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Southfield?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Southfield?
Recruiting research sites in Southfield include Henry Ford Health Providence Southfield Hospital, Michigan Orthopaedic Surgeons, Henry Ford Providence Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Southfield right now?
The largest active categories in Southfield are Cancer & tumors (29), Diabetes & metabolic (9), Cardiovascular (8). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.