Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
for Newly Diagnosed Multiple Myeloma
Sites in St Louis +43 more locations
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT07764978·Phase 3·Recruiting·Listed Aug 14, 2026
Dexamethasone Clinical Trials in St Louis, MO
As of August 2026, 14 paid clinical trials are testing Dexamethasone in St Louis, Missouri. Trials typically compensate participants for time, travel, and study visits, and many also provide study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in St Louis
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
15 clinical trials testing Dexamethasone
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Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
for Prostate Cancer Metastatic
Sites in St Louis +32 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT06136624·Phase 3·Recruiting·Listed Nov 2023
A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma
for Plasma Cell Myeloma Refractory
Sites in St Louis, Kansas City +32 more locations
Sponsor: Sanofi
Sex: All·Age: 18+
Code: NCT06356571·Phase 2·Recruiting·Listed Apr 2024
A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
for Multiple Myeloma
Sites in St Louis +19 more locations
Sponsor: C4 Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT07284758·Phase 2·Recruiting·Listed Dec 2025
Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma
for Multiple Myeloma Refractory
Sites in St Louis +19 more locations
Sponsor: CellCentric Ltd.
Sex: All·Age: 18+
Code: NCT07096778·Phase 2·Recruiting·Listed Jul 2025
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
for Relapsed/Refractory Multiple Myeloma
Drug: Daratumumab
Sites in St Louis +14 more locations
Sponsor: BeOne Medicines
Sex: All·Age: 18+
Code: NCT04973605·Phase 1, Phase 2·Recruiting·Listed Jul 2021
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
for Plasma Cell Myeloma
Sites in St Louis, Ballwin +303 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT04566328·Phase 3·Recruiting·Listed Sep 2020
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in St Louis, Creve Coeur +482 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
for B Acute Lymphoblastic Leukemia
Sites in St Louis, Creve Coeur +153 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18 - 39
Code: NCT03150693·Phase 3·Recruiting·Listed May 2017
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
for B Acute Lymphoblastic Leukemia
Sites in St Louis, Columbia +185 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 365 Days - 25
Code: NCT03959085·Phase 3·Recruiting·Listed May 2019
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
for Plasma Cell Myeloma
Sites in St Louis, Ballwin +387 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: All ages
Code: NCT05561387·Phase 3·Recruiting·Listed Sep 2022
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
for Acute Leukemia of Ambiguous Lineage
Drug: Venetoclax
Sites in St Louis, Kansas City +110 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: Up to 365 Days
Code: NCT06317662·Phase 2·Recruiting·Listed Mar 2024
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
for Down Syndrome
Drug: Nivolumab
Sites in St Louis, Kansas City +148 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 1 - 30
Code: NCT04546399·Phase 2·Recruiting·Listed Sep 2020
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
for Recurrent Lung Non-Small Cell Carcinoma
Drug: Cemiplimab
Sites in St Louis, Creve Coeur +379 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024
Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis
for AL Amyloidosis
Sites in St Louis, Creve Coeur +114 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT06022939·Phase 3·Recruiting·Listed Sep 2023
Top Research Study Locations in St Louis
Researchers run research studies in St Louis, MO at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Washington University School of Medicine | Breast Cancer, Colorectal Cancer, Prostate Cancer | 456 |
| Washington University | Amyotrophic Lateral Sclerosis, CRC, Colorectal Cancer | 137 |
| Washington University in St. Louis | Cardiovascular Diseases, Dementia, Acute Stress Disorder | 87 |
| Mercy Hospital Saint Louis | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8 | 86 |
| Missouri Baptist Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8 | 77 |
| Mercy Hospital South | Stage IV Lung Cancer AJCC v8, Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 76 |
| Siteman Cancer Center-South County | Acute Myeloid Leukemia, Stage IVB Prostate Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 67 |
| Siteman Cancer Center at Christian Hospital | Acute Myeloid Leukemia, Stage IVB Prostate Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 61 |
| Washington University School of Medicine in St. Louis | Ovarian Cancer, Lymphoma, Acute Myeloid Leukemia | 24 |
| Mercy Infusion Center - Chippewa | Malignant Solid Neoplasm, RISS Stage I Plasma Cell Myeloma, RISS Stage II Plasma Cell Myeloma | 23 |
| Cardinal Glennon Children's Medical Center | Neuroblastoma, Osteosarcoma, Ewing Sarcoma | 22 |
| St. Louis Children's Hospital | Adolescent Idiopathic Scoliosis, Advanced Solid Tumor, Autoimmune Hepatitis | 20 |
| Saint Louis University | Opioid Use, ACL Surgery, ALS | 19 |
| Barnes Jewish Hospital | Intracerebral Hemorrhage, Ischemic Stroke, Aortic Aneurysm, Abdominal | 14 |
| Siteman Cancer Center | Breast Cancer, Advanced Hepatocellular Carcinoma, Advanced/Metastatic Urothelial Cancer | 12 |
| Arch Clinical Trials | Schizophrenia, Bipolar Disorder, Bipolar Disorder Type I With Mania | 10 |
| Barnes-Jewish Hospital | Acute Ischemic Stroke, Advanced Hepatocellular Carcinoma, Advanced/Metastatic Urothelial Cancer | 10 |
| Washington University, St. Louis | Acute Myeloid Leukemia, Acute Stress Reaction, Alzheimer Disease | 10 |
| Washington University School of Medicine - Siteman Cancer Center | Advanced Hepatocellular Carcinoma, Advanced Solid Tumors, Adult, Advanced/Metastatic Urothelial Cancer | 9 |
| The Washington University | Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP), Back Pain, Capsular Contracture Associated With Breast Implant | 8 |
| Washington University in St Louis | AML, Adult, Advanced Solid Tumor, Asymptomatic Bacteriuria | 8 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Asthma, Bronchiectasis | 7 |
| St. Louis VA Medical Center John Cochran Division, St. Louis, MO | Anxiety, Carcinoma, Hepatocellular, Chronic Low Back Pain | 7 |
| Washington University Medical Center | ALK-Positive Lung Cancer, ALK-positive NSCLC, ALK-positive Non-small Cell Lung Cancer | 7 |
| Washington University St. Louis | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Advanced Solid Tumors | 7 |
Active & Upcoming Studies in St Louis (2026)
Recruiting trials in St Louis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (545 active studies)
- TeamTalk: Improving Inter-professional Communication During Cancer Treatment · Washington University School of Medicine
- Communication and Hospice Online With Optimal Support and Engagement · Washington University School of Medicine
Neurology & pain (98 active studies)
- Semaglutide for Low Back Pain · Phase 2 · Washington University School of Medicine
- An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD) · Phase 2 · Yale University
Cardiovascular (69 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF · Phase 3 · AstraZeneca
Diabetes & metabolic (46 active studies)
- Semaglutide for Low Back Pain · Phase 2 · Washington University School of Medicine
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
Mental health & behavior (41 active studies)
- Substance Use in Pregnancy - Optimizing Retention in Treatment by Maximizing Opportunities for Management · Phase 2 · Washington University School of Medicine
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Pediatric (22 active studies)
- TeamTalk: Improving Inter-professional Communication During Cancer Treatment · Washington University School of Medicine
- Weight Gain in Pediatric Leukemia Survivors · Washington University School of Medicine
HIV / STI (11 active studies)
- A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1 · Phase 2 · Gilead Sciences
- Menopausal HT for Women Living With HIV (HoT) · Phase 4 · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Eye & vision (11 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
Vaccines (6 active studies)
- A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Characterizing the Human Airway Immune Response to FluMist Vaccination · Phase 4 · Washington University School of Medicine
Common conditions studied in St Louis
- Breast Cancer (37 active studies)
- Prostate Cancer (32 active studies)
- Colorectal Cancer (24 active studies)
- Advanced Solid Tumor (20 active studies)
- Ovarian Cancer (20 active studies)
- Acute Myeloid Leukemia (19 active studies)
Leading research sponsors in St Louis
- Washington University School of Medicine
- National Cancer Institute (NCI)
- AstraZeneca
- Eli Lilly and Company
- SWOG Cancer Research Network
Frequently asked questions
How many paid clinical trials are currently recruiting in St Louis?
There are approximately 1,410 recruiting clinical trials in St Louis, Missouri listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in St Louis pay participants?
Most recruiting trials in St Louis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in St Louis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in St Louis?
The most common conditions under active study in St Louis include Breast Cancer (37), Prostate Cancer (32), Colorectal Cancer (24), Advanced Solid Tumor (20), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in St Louis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in St Louis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in St Louis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in St Louis?
Recruiting research sites in St Louis include Washington University School of Medicine, Washington University, Washington University in St. Louis, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in St Louis right now?
The largest active categories in St Louis are Cancer & tumors (545), Neurology & pain (98), Cardiovascular (69). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
Other cities in Missouri
Kansas City, MO(460)Columbia, MO(227)Springfield, MO(123)City of Saint Peters, MO(92)Cape Girardeau, MO(86)Creve Coeur, MO(74)Farmington, MO(66)Lee's Summit, MO(66)Sainte Genevieve, MO(65)Sullivan, MO(64)Saint Joseph, MO(57)Chesterfield, MO(52)Osage Beach, MO(47)Joplin, MO(43)Rolla, MO(40)Ballwin, MO(37)Bolivar, MO(35)Washington, MO(30)Saint Charles, MO(29)Branson, MO(28)Sunset Hills, MO(23)Jefferson City, MO(22)Liberty, MO(18)Bridgeton, MO(16)Hazelwood, MO(11)North Kansas City, MO(9)O'Fallon, MO(9)Hannibal, MO(8)Independence, MO(8)Town and Country, MO(5)Fenton, MO(4)Florissant, MO(4)Kirksville, MO(4)Weldon Spring, MO(3)Chillicothe, MO(2)Saint Loius, MO(2)Annapolis, MO(1)Belton, MO(1)Bethany, MO(1)Carrollton, MO(1)Carthage, MO(1)Clinton, MO(1)Des Peres, MO(1)Excelsior Springs, MO(1)Festus, MO(1)Frontenac, MO(1)Kansa City, MO(1)Lake Saint Louis, MO(1)Lebanon, MO(1)Louis, MO(1)Manchester, MO(1)Marshall, MO(1)Overland, MO(1)Overland Park, MO(1)Ozark, MO(1)Poplar Bluff, MO(1)Raymore, MO(1)Raytown, MO(1)Roseville, MO(1)Royal Oak, MO(1)