Oncology Clinical Trials in York, PA
As of August 2026, 37 paid clinical trials are recruiting for Oncology in York, Pennsylvania. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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37 clinical trials for Oncology
·Clear filters·Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
GEMINI-NSCLC: NSCLC Biomarker Study
TEMPUS ARIES: A Biobank Registry Platform Study in Oncology
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Prospective Study to Assess a Diagnostic Aid for Cancer
A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)
Tempus Small Cell Lung Cancer Observational Study (Sculptor)
A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
E-Mindfulness Approaches for Living After Breast Cancer
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Customized TULSA-PRO Ablation Registry
Use of an Intrauterine Manipulator and Its Correlation with Positive Peritoneal Cytology in Early Stage Endometrial Cancers
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
Top Research Study Locations in York
Researchers run research studies in York, PA at 22 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cancer Care Associates of York | Cancer, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | 24 |
| WellSpan Health-York Cancer Center | Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 22 |
| WellSpan Health-York Hospital | Stage IV Lung Cancer AJCC v8, Metastatic Malignant Neoplasm in the Brain, Stage IIIB Lung Cancer AJCC v8 | 15 |
| UPMC Memorial | Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 14 |
| WellSpan Health | Acute Ischemic Stroke, Atrial Fibrillation, Coronary Artery Disease | 10 |
| WellSpan York Hospital | Aneurysm, Brain, Coronary Artery Disease, Osteoarthritis | 7 |
| York Hospital | Atrial Fibrillation, Coronary Arterial Disease (CAD), de Novo Lesions in Native Coronary Arteries | 3 |
| Heart and Vascular Research at WellSpan Health | Atherosclerosis, Cardiovascular Diseases, Coronary Artery Disease | 2 |
| WellSpan Oncology Research | Carcinoma, Non-Small-Cell Lung, Non-Small Cell Lung Cancer (NSCLC) | 2 |
| WellSpan York Cancer Center | Advanced Malignant Neoplasm, Advanced Solid Tumor, Breast Cancer | 2 |
| WellSpan Health York Hospital | Esophageal Foreign Body, Esophageal Obstruction, Rib Fracture Multiple | 2 |
| Ability x Ottobock.care | Lower Extremity, Pareses | 1 |
| Cancer Care Associates of York, Inc. | Breast Cancer | 1 |
| Cancer Care Association of York | Small Cell Lung Cancer | 1 |
| MD@Home | Pharmacogenomic Testing for Medication Management | 1 |
| OSS Health Powder Mill | Lumbar Spinal Stenosis | 1 |
| WellSpan Health (The Gene Health Project) | Genetic Predisposition to Disease, Genetics Disease | 1 |
| WellSpan Health - York Cancer Center | Breast Carcinoma, Colorectal Carcinoma, Lung Non-Small Cell Carcinoma | 1 |
| WellSpan Health, York Hospital | Coronary Artery Disease (CAD), Coronary Calcification, Coronary Calcified Disease | 1 |
| WellSpan Heart & Vascular | Coronary Artery Disease | 1 |
| WellSpan Heart and Vascular Research | Percutaneous Coronary Intervention, Peripheral Endovascular Intervention | 1 |
| Wellspan Gynecologic Oncology | Ovarian Cancer | 1 |
Active & Upcoming Studies in York (2026)
Recruiting trials in York grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (63 active studies)
- A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202) · Phase 3 · Bristol-Myers Squibb
- A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer · Phase 3 · Incyte Corporation
Cardiovascular (13 active studies)
- Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI) · Supira Medical
- A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation · Biosense Webster, Inc.
Neurology & pain (2 active studies)
- Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial · Phase 3 · Mercy Health Ohio
- Stroke Thrombectomy and Aneurysm Registry · Medical University of South Carolina
Mental health & behavior (1 active study)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Common conditions studied in York
- Stage IV Lung Cancer AJCC v8 (6 active studies)
- Coronary Artery Disease (5 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Breast Cancer (4 active studies)
- Head and Neck Squamous Cell Carcinoma (4 active studies)
- Non-Small Cell Lung Cancer (4 active studies)
Leading research sponsors in York
- NRG Oncology
- SWOG Cancer Research Network
- AstraZeneca
- Tempus AI
- WellSpan Health
Frequently asked questions
How many paid clinical trials are currently recruiting in York?
There are approximately 94 recruiting clinical trials in York, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in York pay participants?
Most recruiting trials in York compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in York?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in York?
The most common conditions under active study in York include Stage IV Lung Cancer AJCC v8 (6), Coronary Artery Disease (5), Anatomic Stage II Breast Cancer AJCC v8 (4), Breast Cancer (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in York?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in York on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in York?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in York?
Recruiting research sites in York include Cancer Care Associates of York, WellSpan Health-York Cancer Center, WellSpan Health-York Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in York right now?
The largest active categories in York are Cancer & tumors (63), Cardiovascular (13), Neurology & pain (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.