Alcohol use disorder Clinical Trials

Recruiting alcohol use disorder studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat alcohol use disorder. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting alcohol use disorder studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting alcohol use disorder trials

Within

A Digital Pill System to Measure and Support Acamprosate Adherence in Individuals With Alcohol Associated Liver Disease

for Alcohol Use Disorder

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT07553377

Adapting a Telehealth Intervention for Suicide Prevention Among Patients With Alcohol Use Disorder in Tanzania

for Alcohol Use Disorder

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07475988

TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD)

for Alcohol Use Disorder

1 site in Portland

Sponsor: Washington State University

Sex: All·Age: 18+

Code: NCT07171359

Apply to this trial

A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults

for Alcohol Use Disorder

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 29

Code: NCT07214831

Preventing Harmful Alcohol Use Among Trauma Patients in Cameroon

for Alcohol Use Disorder

Sponsor: University of Buea

Sex: All·Age: 18+

Code: NCT07677449

ETSF for Latinx Young Adults with Alcohol Use Disorder

for Alcohol Use Disorder (AUD)

Sponsor: Tulane University

Sex: All·Age: 18 - 29

Code: NCT06722690

Daridorexant for Alcohol Use Disorder

for Alcohol Use Disorder

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07532252·Phase 2

Pomegranate Dietary Supplements in AUD and ALD

for Alcohol Use Disorder

1 site in Louisville

Sponsor: University of Louisville

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07678567

Effectiveness of Nurse-Conducted Brief Intervention (NCBI) Supplemented With Mobile for Preventing Alcohol Use Disorders

for Alcohol Use Disorder (AUD)

Sponsor: University of Pittsburgh

Sex: Male·Age: 18 - 59

Code: NCT06652802

Testing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery (CalmiFy II)

for Alcohol Use Disorder (AUD)

Sponsor: Washington State University

Sex: All·Age: 18 - 35

Code: NCT07088237

Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples

for Alcohol Drinking

Sponsor: University of Washington

Sex: All·Age: 18 - 29·Accepts healthy volunteers

Code: NCT06422299

Combination Therapy for Alcohol Use Disorder

for Alcohol Use Disorder

1 site in Havre de Grace

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 65

Code: NCT07249554·Phase 2

Deaf CBT-TS to Reduce Suicide Risk

for Depression - Major Depressive Disorder

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT07279363

Pilot Study: Effects of Nimodipine on Alcohol Drinking

for Alcohol Use Disorder

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 21 - 50

Code: NCT06900998·Phase 2

High Intensity Use of Urgent and Emergency Care: A Mixed-Methods Study

for High Intensity Use of Urgent and Emergency Care

Sponsor: Bournemouth University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07630012

Effects of Nimodipine on Alcohol Drinking

for Alcohol Use Disorder

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 21 - 50

Code: NCT07681869·Phase 2

Daridorexant for People With Insomnia and Alcohol Use Disorder Study

for Alcohol Use Disorder

1 site in Spokane

Sponsor: Sterling McPherson

Sex: All·Age: 18+

Code: NCT07701928·Phase 2

Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study

for Cannabis Use Disorder

1 site in San Bernardino

Sponsor: Loma Linda University

Sex: All·Age: 18+

Code: NCT07001371

Peer Support for Liver Transplant Recipients With History of ALD

for Alcohol Use Disorder

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07397598

Elastography-based Brief Alcohol Intervention in Hospitalized Individuals

for Alcoholic Liver Disease (ALD)

Sponsor: Oslo University Hospital

Sex: All·Age: 18+

Code: NCT07637539

mHealth-supported Skills Training for Alcohol-Related Suicidality Phase 3

for Alcohol Drinking

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT05847582

Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder

for Alcohol Use Disorder

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 65

Code: NCT06807918·Phase 2, Phase 3

Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving

for Alcohol Use Disorder (AUD)

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 65

Code: NCT07148843·Phase 2, Phase 3

Financial Rewards for Reducing Alcohol Use in Patients With Liver Disease

for Alcohol Use Disorder

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07465588

Social Identity Mapping for Adolescent Recovery

for Alcohol Use Disorder (AUD)

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12 - 19

Code: NCT07474207

OEA for Young Adults With Alcohol Use Disorder

for Alcohol Use Disorder (AUD)

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 25

Code: NCT07503782·Phase 2

Environment and Alcohol: A Pilot Study

for Alcohol Use Disorder

1 site in Baltimore

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 21 - 100·Accepts healthy volunteers

Code: NCT06860607·Phase 1

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Hepatic Lipid Metabolism-Alcohol Use Disorder

for Alcohol Use Disorder

1 site in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 100

Code: NCT07191561

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Prevention of Relapse Through Cognitive Cycling in Patients With Alcohol Use Disorder Following Alcohol Withdrawal

for Cognitive Cycling

Sponsor: Centre Hospitalier Esquirol

Sex: All·Age: 18+

Code: NCT07690423

Supporting Adolescent Alcohol Treatment With Computer-Based ('Path180') Skills Training

for Alcohol Use Disorder

1 site in Providence

Sponsor: Brown University

Sex: All·Age: 13 - 19·Accepts healthy volunteers

Code: NCT07713251

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Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of a GLP-1 Receptor Agonist Semaglutide in U.S. Veterans With Alcohol Use Disorder

for Alcohol Use Disorder

1 site in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07218354·Phase 3

Effects of Olfactory Stimuli in Virtual Reality Cue Exposure on Craving and Attentional Bias in Alcohol Use Disorder

for Alcohol Use Disorder

Sponsor: Charite University, Berlin, Germany

Sex: All·Age: 18 - 65

Code: NCT07667790

Body-Focused Mindfulness as an Add-on Intervention in Inpatient Alcohol Use Disorder Treatment (MBI-AUD-PL)

for Alcohol Use Disorder (AUD)

Sponsor: Medical University of Warsaw

Sex: All·Age: 18+

Code: NCT07706660

Impact of Federal and State Medications for Opioid Use Disorder (MOUD) Policy Changes During the Pandemic

for Substance Use Disorders

1 site in Boston

Sponsor: Boston University

Sex: All·Age: 18+

Code: NCT07232641

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Endotoxin Exposure to Examine the Role of Inflammation in Alcohol Use

for Alcohol Use Disorder

Sponsor: University of California, Los Angeles

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07452146·Phase 2

Process-Based Psychological Processes in Alcohol Use Disorder: A Case-Control Study Using PBAT, PHQ-9, and GAD-7

for Alcohol Use Disorder (AUD)

Sponsor: George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07551830

Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms

for Alcohol Use Disorder

Sponsor: Centre Hospitalier Universitaire de Nīmes

Sex: All·Age: 18+

Code: NCT07638553·Phase 3

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The Effect of Comorbid Alcohol/Substance Use

for Alcohol Abuse

Sponsor: Abant Izzet Baysal University

Sex: All·Age: 18 - 65

Code: NCT07692984

Apply to this trial

Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder

for Alcohol Use Disorder

1 site in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65

Code: NCT07296094·Phase 2

Tirzepatide in MetALD

for Metabolic Alcohol-associated Liver Disease

1 site in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 21 - 100

Code: NCT07046819·Phase 2

Apply to this trial

Reset Challenge: Reducing High-risk Drinking for Cancer Prevention

for Alcohol Drinking

1 site in Tulsa

Sponsor: University of Oklahoma

Sex: All·Age: 18 - 120

Code: NCT07591428

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Targeting Alcohol-Opioid Co-Use Among Young Adults Using a Novel MHealth Intervention

for Alcohol Drinking

1 site in Providence

Sponsor: Brown University

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT07663448

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Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, Kenya

for HIV

Sponsor: University of Chicago

Sex: All·Age: 18 - 80

Code: NCT06790342·Phase 3

Coordinated Care for Alcohol Problems

for Alcohol Use Disorder

Sponsor: Sangath

Sex: Male·Age: 18+

Code: NCT07260149

Imaging CRF X NOP Interactions in Alcohol Use Disorder

for Alcohol Use Disorder

1 site in Pittsburgh

Sponsor: Rajesh Narendran

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07612631·EARLY_Phase 1

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Methylphenidate and Response to Alcohol Cues

for Alcohol Use Disorder

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT07306078·Phase 2

Evaluation of a Virtual Reality-based Version of the Multiple Errands Test in Alcohol Use Disorder

for Alcohol Use Disorder (AUD)

Sponsor: Hôpital le Vinatier

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07593664

Efficacy and Safety of Alcovit in Reducing Blood Alcohol Concentration

for Alcohol Drinking

Sponsor: Galzu Institute of Research, Teaching, Science and Applied Technology

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07332429

Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)

for Alcohol Use Disorder (AUD)

1 site in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 21 - 65

Code: NCT07559500·Phase 1

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MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

for Post Traumatic Stress Disorder

2 sites incl. West Haven

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07118839·Phase 2, Phase 3

Apply to this trial

Acceptability and Feasibility Study of Non-alcoholic Beverages

for Alcohol Use Disorder (AUD)

1 site in Stanford

Sponsor: Stanford University

Sex: All·Age: 21 - 89

Code: NCT07451574

Effects of Ketogenic Diet on Alcohol Intoxication

for Ketogenic Diet

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 50·Accepts healthy volunteers

Code: NCT07602270

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Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder

for Alcohol Use Disorder

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07029529·Phase 2

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Social Cognition in Severe Alcohol Use Disorder

for Alcohol Use Disorder

Sponsor: CHU de Reims

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07464613

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GLP-1 RA on Alcohol Consumption, Metabolism and Liver Parameters in Patients With Obesity and Fatty Liver Disease

for Adiposity

Sponsor: Insel Gruppe AG, University Hospital Bern

Sex: All·Age: 18 - 80

Code: NCT06546384

Exploration of Acceptability of Alcohol Interventions

for Alcohol Misuse

Sponsor: East Lancashire Hospitals NHS Trust

Sex: All·Age: 18 - 67·Accepts healthy volunteers

Code: NCT07580378

Multimodal Immune and Neuroendocrine Assessment in Drinkers

for Alcohol Drinking

1 site in Auburn

Sponsor: Auburn University

Sex: All·Age: 21 - 25·Accepts healthy volunteers

Code: NCT07220148

LDART for Alcohol Use Disorder

for Alcohol Use Disorder

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT07221383

Identification and Molecular Characterisation of Urban-environmental Stress Patterns Affecting Mental Illness

for Major Depressive Disorder (MDD)

Sponsor: Huashan Hospital

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07571226

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An Effectiveness Trial of the PrEP for WINGS Study

for HIV Infections

1 site in New York

Sponsor: Columbia University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06853314

Apply to this trial

Alcohol use disorder clinical trials — common questions

Are alcohol use disorder clinical trials free to join?

Yes. Participating in a alcohol use disorder clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a alcohol use disorder clinical trial?

Each alcohol use disorder study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a alcohol use disorder trial near me?

Use the location controls above. We'll show recruiting alcohol use disorder trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many alcohol use disorder trials are recruiting right now?

We're currently tracking roughly 208 recruiting alcohol use disorder trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Alcohol use disorder trials by city

Boston, MA Seattle, WA Ann Arbor, MI Indianapolis, IN Los Angeles, CA Palo Alto, CA Spokane, WA Aurora, CO Columbus, OH Chicago, IL Portland, OR San Diego, CA

Related specialties

Behavioral health Addiction medicine