Delirium Clinical Trials

Recruiting delirium studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat delirium. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting delirium studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting delirium trials

Within

Post-surgical Delirium in Patients Undergoing Radical Cystectomy.

for Delirium

Sponsor: University of Alexandria

Sex: All·Age: 18 - 99

Code: NCT03806439

Post-surgical Delirium in Patients Undergoing Open Heart Surgery.

for Delirium

Sponsor: University of Alexandria

Sex: All·Age: 18 - 99

Code: NCT03806413

Analysis of Weaning of Analgosedation and Kinetics of Emergence in Critically Ill Patients

for Critical Illness

Sponsor: Patricia Rodriguez Villamizar

Sex: All·Age: 18+

Code: NCT07710066

Predictors of Cognitive Decline and Delirium in Older Women With Ovarian Cancer

for Ovarian Cancer

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: Female·Age: 70+

Code: NCT07716800

Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle

for Sleep

Sponsor: University of Alberta

Sex: All·Age: 18+

Code: NCT06824077·EARLY_Phase 1

Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery

for Postoperative Cognitive Complications

1 site in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT07577726

Bedside Bike Early Mobilization Program for Inpatients

for Immobility Syndrome

Sponsor: Indiana University

Sex: All·Age: 18 - 110·Accepts healthy volunteers

Code: NCT07281638

Respiratory Physiotherapy and PMR After Cardiac Surgery

for Cardiac Surgery

Sponsor: Istanbul Aydın University

Sex: All·Age: 18 - 80

Code: NCT07542691

EEG-TMS for Postoperative Delirium After Cardiac Surgery

for Delirium

Sponsor: RenJi Hospital

Sex: All·Age: 50+

Code: NCT07537725

VR-Based Cognitive Stimulation Games for Delirium Prevention

for Surgery

2 sites in Houston

Sponsor: The Methodist Hospital Research Institute

Sex: All·Age: Up to 65

Code: NCT07641153

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Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery

for Delirium

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 60+

Code: NCT06969287·Phase 3

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Lemborexant for Sleep and Delirium Prevention in Elderly ICU Patients

for Sleep Disturbance

Sponsor: Mahidol University

Sex: All·Age: 65+

Code: NCT07407400·Phase 4

Fecal Microbiota Transplantation for the Treatment of ICU Delirium

for Delirium

Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Sex: All·Age: 18 - 80

Code: NCT07348471

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Delirium in Neurodegenerative Disease Patients: A Music Therapy Intervention for Hospital Care

for Delirium

1 site in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 60+

Code: NCT07137949

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A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Profile of Gastrodin Injection in Healthy Chinese Subjects

for Delirium

Sponsor: Kunming Pharmaceuticals, Inc.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07422142·Phase 1

Computer-assisted Cognitive Stimulation Treatment for Delirium

for Delirium

Sponsor: Institut Investigacio Sanitaria Pere Virgili

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07563244

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Clinical Application of Listening to Music to Prevent Delirium in the Intensive Care Unit

for Critical Illness

Sponsor: HOSPITAL BRITANICO DE BUENOS AIRES

Sex: All·Age: 65+

Code: NCT07369258

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Research on the Development and Validation of an Early Prediction Model for Delirium

for Delirium

Sponsor: Ruijin Hospital

Sex: All·Age: 18+

Code: NCT07337356

Quality Improvement Project to Reduce Preoperative Fasting Times Before Elective Procedures

for Preoperative Fasting

Sponsor: University of Giessen

Sex: All·Age: All ages

Code: NCT07488468

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Remimazolam vs Midazolam to Reduce Delirium in Adults ≥65 Undergoing CPB Valve Surgery

for Delirium

Sponsor: Yonsei University

Sex: All·Age: 65 - 99

Code: NCT07265128·Phase 4

Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients

for Aged

Sponsor: Peking University First Hospital

Sex: All·Age: 18+

Code: NCT06468436

Effects of Artificial Intelligence Nurse Orientation Program on Psychological Outcomes and Length of Hospital Stay in Intensive Care Unit

for Delirium

Sponsor: Koç University

Sex: All·Age: 18+

Code: NCT07171944

TaVNS for Delirium

for Delirium Treatment

1 site in Stony Brook

Sponsor: Stony Brook University

Sex: All·Age: 22+

Code: NCT07258082

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Effect of a Virtual Reality Program on Patient Comfort in the Surgical Intensive Care Unit

for Immersive Virtual Reality

Sponsor: Centre Hospitalier Universitaire, Amiens

Sex: All·Age: 18+

Code: NCT06830369

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Sedation and Analgesia Bundled Strategies Among ICU Nurses

for Sedation and Analgesia

Sponsor: Ruijin Hospital

Sex: All·Age: 18+

Code: NCT07132450

Development and Validation of Delirium Recognition Using Computer Vision in Neuro-critical Patients

for Delirium

Sponsor: Beijing Tiantan Hospital

Sex: All·Age: 18 - 80

Code: NCT07136207

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VoiceLove Digital Therapy for Delirium in the ICU

for Delirium

1 site in Houston

Sponsor: The Methodist Hospital Research Institute

Sex: All·Age: 18+

Code: NCT07218484

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Delirium and Cognitive Impairment Development in Hospitalized Older Adults Under Isolation Conditions

for Delirium

Sponsor: Universitätsklinikum Hamburg-Eppendorf

Sex: All·Age: 70+

Code: NCT07114458

Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study

for Delirium

Sponsor: Herlev Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06974214

Comparison of Haloperidol and Dexmedetomidine for Delirium and Agitation in ICU Patients With Traumatic Brain Injury

for Traumatic Brain Injury

Sponsor: Benha University

Sex: All·Age: 18+

Code: NCT06993194

Stanford-Lucidify EEG Delirium Study

for Delirium

1 site in Stanford

Sponsor: Stanford University

Sex: All·Age: 55+

Code: NCT06999967

ABCDEF Bundle to Prevent Delirium for COPD Patients

for Delirium

Sponsor: Istanbul Saglik Bilimleri University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06974318

Effects of Nonpharmacological Interventions in Sleep Quality, Anxiety, and Delirium for Patients of Adult Intensive Care Units

for Intensive Care Unit

Sponsor: Chiayi Christian Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06774599

Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)

for Delirium

14 sites incl. Los Angeles

Sponsor: Massachusetts General Hospital

Sex: All·Age: 60+

Code: NCT06192615·Phase 3

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A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors

for Critical Illness

1 site in Seattle

Sponsor: University of Washington

Sex: All·Age: 60+

Code: NCT06411561

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Simultaneous Recumbent Cycling and Cognitive Training

for Delirium

1 site in Kansas City

Sponsor: University of Missouri, Kansas City

Sex: All·Age: 45 - 64

Code: NCT04556227

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Effect of Nasal Spray Dexmedetomidine on Emergence Delirium Prevention in Total Hip Replacement

for Delirium

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Sex: All·Age: 60+

Code: NCT06579001·Phase 4

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Music for Surgical Intensive Care (MUSIC)

for DELIRIUM

Sponsor: D'Or Institute for Research and Education

Sex: All·Age: 65+

Code: NCT06657040

Light and Noise: Objectively Assessing Environmental Risk Factors for Delirium in the ICU

for Delirium

Sponsor: Medical University of Graz

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06294158

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Comparative Analysis of Delirium in Older Adults Treated With Ceftazidime, Cefepime, or Ceftriaxone

for Delirium

Sponsor: Alexandria University

Sex: All·Age: 65+

Code: NCT07026253

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The Use of Melatonin for Delirium Prevention in Medically Hospitalized Patients

for Delirium

Sponsor: Sultan Qaboos University

Sex: All·Age: 65+

Code: NCT06509191·Phase 2, Phase 3

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The Trajectory and Influencing Factors of Cognitive Level in ICU Delirium Patients After Transfer Out of the ICU

for Cognition Disorder

Sponsor: Zunyi Medical College

Sex: All·Age: 18+

Code: NCT06674603

Transcranial Alternating Current Stimulation on Patients with Delirium and Critical Illness (DeliTACS)

for Delirium

Sponsor: Kuopio University Hospital

Sex: All·Age: 18+

Code: NCT06460363

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DeliKet (Substudy of KetoNiFast Study ID 22-1398_1)

for Delirium

Sponsor: University Hospital of Cologne

Sex: All·Age: 18+

Code: NCT06535022

Neurosteer Bedside Monitoring System

for Delirium

1 site in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT06718764

Apply to this trial

Behavioral Economic & Staffing Strategies in the ICU

for Implementation Science

3 sites incl. Iowa City

Sponsor: University of Nebraska

Sex: All·Age: 19+

Code: NCT06184945

Apply to this trial

Anticoagulation and Inflammation Monitoring in Patients After Heart and Vascular Interventions

for Heart Surgery

Sponsor: Medical University Innsbruck

Sex: All·Age: 18+

Code: NCT06222866

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Modifying the Inpatient Environment to Reduce Delirium in Older Adults

for Delirium

5 sites incl. Baytown

Sponsor: Farhaan S. Vahidy

Sex: All·Age: 70+

Code: NCT06736951

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Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery

for Delirium, Postoperative

Sponsor: Auckland City Hospital

Sex: All·Age: 55+

Code: NCT06268080

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DEliriuM in STroke: the Link Between Stroke, Delirium and Long-term Cognitive Impairment

for Ischemic Stroke

Sponsor: Universitair Ziekenhuis Brussel

Sex: All·Age: 18+

Code: NCT06650436

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Delirium Treatment With Transcranial Electrical Stimulation

for Delirium

Sponsor: A.J.C. Slooter

Sex: All·Age: 50+

Code: NCT06285721

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Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department

for Delirium

1 site in Columbus

Sponsor: Ohio State University

Sex: All·Age: 65+

Code: NCT06326424

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Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation

for Delirium

2 sites incl. Boston

Sponsor: Penn State University

Sex: All·Age: 70+

Code: NCT05915377

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Delirium Phenotypes and Subsequent Impairment During Transition From ICU to Hospital Wards

for Delirium

Sponsor: Shanghai Zhongshan Hospital

Sex: All·Age: 18 - 100

Code: NCT07193797

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Effectiveness of a Virtual Reality-Based Sensory Stimulation Intervention in Preventing Delirium in Intensive Care Units

for Delirium

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 18 - 90

Code: NCT06153472

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

for Delirium

1 site in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 65+

Code: NCT05461092·EARLY_Phase 1

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VR Interventions to Reduce the Prevalence of Delirium in ICU Patients

for Delirium

Sponsor: Peking Union Medical College Hospital

Sex: All·Age: 18 - 90

Code: NCT05525702

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Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders

for Delirium

7 sites incl. Orange

Sponsor: University of Michigan

Sex: All·Age: 70+

Code: NCT05929703

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CTSN Embolic Protection Trial

for Delirium

19 sites incl. North Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788

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Delirium in the (Neuro)Intensive/Critical Care in the Adult and Paediatric Czech Populations

for Delirium

Sponsor: Masaryk University

Sex: All·Age: All ages

Code: NCT05891873

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Delirium clinical trials — common questions

Are delirium clinical trials free to join?

Yes. Participating in a delirium clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a delirium clinical trial?

Each delirium study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a delirium trial near me?

Use the location controls above. We'll show recruiting delirium trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many delirium trials are recruiting right now?

We're currently tracking roughly 26 recruiting delirium trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Delirium trials by city

Boston, MA Columbus, OH Gainesville, FL Los Angeles, CA Madison, WI Orange, CA Seattle, WA Stanford, CA

Related specialties

Geriatrics