Hematologic malignancy Clinical Trials

Recruiting hematologic malignancy studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat hematologic malignancy. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting hematologic malignancy studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting hematologic malignancy trials

Within

Aberrant Expression of CD56 in Patients With Hematologic Malignancies.

for Hematologic Malignancies

Sponsor: Asmaa Hassan mohamed Abdel Mawjoud

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04546945

Apply to this trial

The High Fiber Program to Increase Fiber Intake Among Patients Undergoing Allogeneic Hematopoietic Cell Transplant

for Hematopoietic and Lymphatic System Neoplasm

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07664670

Adoption of Audio Recording in the Outpatient Supportive Care Center

for Advanced Malignant Solid Neoplasm

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04871477

Wearable Data for Personalized Prognostication in Cancer: A Registry Protocol

for Hematopoietic Neoplasm

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07691008

Study to Characterize Mismatched to Fully HLA-Matched Ossium HPC, Marrow and Living Donor Transplantation in Patients With Hematologic Malignancies

for Hematologic Malignancy

Sponsor: Ossium Health, Inc.

Sex: All·Age: 12 - 75

Code: NCT07710781

Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation

for Graft Versus Host Disease

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 7+

Code: NCT07235501

Apply to this trial

Evaluating the Effects of Propionate and Butyrate Supplementation on the Intestinal Health of Healthy Volunteers

for Graft Versus Host Disease

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07611370·Phase 1

A Wearable Biosensor Patch for Non-Invasive Monitoring for Patients Undergoing Abdominal or Chest Surgery

for Hematopoietic and Lymphatic System Neoplasm

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07612085

Virtual Reality Viewing of Unaltered Streetscape Versus Digitally Manipulated Opposite Streetscape to Assess Psychosocial Response in Participants

for Hematopoietic and Lymphatic System Neoplasm

1 site in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07216534

Apply to this trial

Self-Amplifying mRNA COVID-19 Vaccine (LUNAR-COV19) Versus Comirnaty Vaccine in Adult Hematopoietic Cell Transplant Patients

for Hematopoietic and Lymphatic System Neoplasm

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07390968·Phase 2

A Spiritual Health Intervention (PATH) for Improving Spiritual, Religious and Emotional Distress in Cancer Patients

for Hematopoietic and Lymphatic System Neoplasm

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07545291

Cannabis Gummy for the Improvement of Sleep and Quality of Life in Patients With Cancer, Pillow Trial

for Hematopoietic and Lymphatic System Neoplasm

1 site in Columbus

Sponsor: Theodore Brasky PhD

Sex: All·Age: 18+

Code: NCT07658677·Phase 1, Phase 2

Rutgers University Study of the Genetics of Blood Cancers

for Blood Cancers

1 site in Piscataway

Sponsor: Rutgers, The State University of New Jersey

Sex: All·Age: 18 - 110·Accepts healthy volunteers

Code: NCT07714044

A Clinical Trial of MK-1045 in People With B-cell Cancer (MK-1045-006)

for Chronic Lymphocytic Leukaemia

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07709000·Phase 2

Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids

for Hematopoietic and Lymphatic System Neoplasm

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 18 - 75

Code: NCT06827054·Phase 2

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

for Relapsed Pediatric ALL

1 site in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT07257419·Phase 1

Apply to this trial

Transcranial Direct Current Stimulation for the Treatment of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors

for Chemotherapy-Induced Peripheral Neuropathy

1 site in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18 - 85

Code: NCT07673614

Assessing DCog Short for Neurotoxicity in CAR-T

for Neurotoxicity

1 site in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT07403812

Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease

for Chronic Graft Versus Host Disease

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07535008

Apply to this trial

CD45RA-depleted DLI for the Prevention of Viral Infections in High-risk Patients After Haploidentical Transplantation

for Hematologic Malignancy

Sponsor: Ruijin Hospital

Sex: All·Age: 14 - 50

Code: NCT07672964·Phase 1

Role of Viscoelastometric Testing in the Development and Validation of a Clinical-biological Score for Predicting Bleeding in Patients With Malignant Haematological Disorders and Severe Thrombocytopenia

for Thrombocytopenia

Sponsor: Centre Hospitalier Annecy Genevois

Sex: All·Age: 18+

Code: NCT07653672

Clinical Study of the Safety and Efficacy of Allogeneic TCR-enhanced Vδ2 T Cell in Patients With Malignant Tumors.

for Hematologic Malignancy

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 18 - 75

Code: NCT07570563·Phase 1, Phase 2

Apply to this trial

Community-Based Exercise and Nutrition Training and Education Program for Cancer Survivors

for Hematopoietic and Lymphatic System Neoplasm

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 18+

Code: NCT06565260

Apply to this trial

Axatilimab Plus Standard of Care Therapy for the Prevention of Graft Versus Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Hematologic Cancer, ABRAXAS Trial

for Hematopoietic and Lymphatic System Neoplasm

3 sites incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07349771·Phase 2

Early Discontinuation of Antibiotics in Paediatric High-risk Febrile Neutropenia

for Febrile Neutropenia (FN)

Sponsor: Hospital Universitari Vall d'Hebron Research Institute

Sex: All·Age: Up to 18

Code: NCT07590648·Phase 4

CD45RA-depleted DLI for the Treatment of Refractory/Persistent Viral Infections After Haploidentical Transplantation

for Hematologic Malignancy

Sponsor: Ruijin Hospital

Sex: All·Age: All ages

Code: NCT07662369·Phase 1, Phase 2

Apply to this trial

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

for Anxiety

1 site in Seattle

Sponsor: University of Washington

Sex: All·Age: 18 - 85

Code: NCT07336238·Phase 2

Apply to this trial

Phase I Randomized Controlled Trial of Functional Resistance Training in Older Cancer Survivors: The ACES Trial

for Hematopoietic and Lymphatic System Neoplasm

1 site in Portland

Sponsor: OHSU Knight Cancer Institute

Sex: All·Age: 65+

Code: NCT07606313

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

3 sites incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07020533·Phase 1

Apply to this trial

Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

for Hematopoietic and Lymphatic System Neoplasm

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07025538·Phase 1

Apply to this trial

L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance

for Hematopoietic and Lymphatic System Neoplasm

4 sites incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07220447·EARLY_Phase 1

Apply to this trial

Allergy Delabeling in Antibiotic Stewardship - Intervention

for Beta Lactam Allergy

1 site in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07133074·Phase 4

Apply to this trial

A Culturally Informed Patient Navigation Program (CFPN) to Reduce Delays Between Diagnosis and Treatment in American Indian and Alaska Native Cancer Patients Living in Rural California

for Hematopoietic and Lymphatic System Neoplasm

2 sites incl. Bishop

Sponsor: University of Southern California

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07332312

Apply to this trial

Telephone-Based Coaching Sessions (TAC) to Improve Advance Care Planning Participation in Advanced Cancer Patients and Their Support Person

for Advanced Malignant Solid Neoplasm

3 sites incl. Everett

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07141407

Apply to this trial

A Study of BL-M24D1 in Patients With Relapsed or Refractory Multiple Myeloma and Other Hematologic Malignancies

for Multiple Myeloma

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT07255898·Phase 1

Apply to this trial

Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention

for Graft-versus-Host Disease (GVHD)

1 site in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT06926595·Phase 2

Apply to this trial

Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

for Leukemia

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT06856226

Apply to this trial

Comparing the Efficacy of Different Durations of Maribavir Treatment Regimens in Allo-HSCT

for Hematologic Malignancy

Sponsor: Ruijin Hospital

Sex: All·Age: 18 - 75

Code: NCT07511127·Phase 3

Apply to this trial

A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment

for Chemotherapy-Induced Peripheral Neuropathy

1 site in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT07365007

Apply to this trial

The Safety and Efficacy of the Regimen of Thiotepa + Fludarabine +Granulocyte Colony-Stimulating Factor+ Cytarabine + Busulfan in Single Unrelated Umbilical Cord Blood Transplantation

for Hematologic Malignancies

Sponsor: Institute of Hematology & Blood Diseases Hospital, China

Sex: All·Age: 60 - 69

Code: NCT07441967·Phase 2

Prevalence and Clinical Manifestations of Cannabis Withdrawal in Hospitalized Patients With Hematological Malignancies Undergoing Bone Marrow Transplant (BMT) or Chimeric Antigen Receptor T-Cell (CAR-T) Therapy

for Hematopoietic and Lymphatic System Neoplasm

1 site in Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07594496

Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer

for Hematopoietic and Lymphatic System Neoplasm

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07477886

Apply to this trial

Expressive Writing Program Among Young Adults With Blood Cancer

for Hematologic Malignancy

1 site in Washington D.C.

Sponsor: Blood Cancer United

Sex: All·Age: 18+

Code: NCT07413991

Apply to this trial

Long-Term Follow-Up of AvenCell Sponsored CAR-T Cell Clinical Trials

for B-cell Lymphoma

Sponsor: AvenCell Therapeutics, Inc.

Sex: All·Age: All ages

Code: NCT07474051

ONC-MM-2407: The Effect of Virtual Reality Headsets on Pain and Anxiety in the Peri and Post Bone Marrow Biopsy Period

for Hematologic Malignancy

1 site in Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07203534

Apply to this trial

Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

for B-ALL

6 sites incl. Aurora

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT06579469

Apply to this trial

A Study of Ruxolitinib for Preventing Graft-Versus-Host Disease in People With a Hematologic Malignancy Who Will Receive a Stem Cell Transplant

for Hematologic Malignancies

7 sites incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07359859·Phase 2

Apply to this trial

Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment

for Hematologic Malignancy

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06532773

Apply to this trial

Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy

for Hematologic Malignancies

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07186192·Phase 3

Apply to this trial

Understanding Needs of Older Patients Prior to Starting Cancer Treatment

for Hematopoietic and Lymphatic System Neoplasm

24 sites incl. Tuscaloosa

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225920

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

for Solid Tumors

8 sites incl. Duarte

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07195916·Phase 1

Apply to this trial

Feasibility and Acceptability of Primary Palliative Care Intervention in Patients Undergoing Hematopoietic Stem Cell Transplantation

for Hematopoietic Cell Transplant

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06676852

Apply to this trial

Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

for Hematopoietic and Lymphatic System Neoplasm

3 sites incl. Duarte

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT06817889·Phase 2

Apply to this trial

A Clinical Study of Allogenic CD19-CAR-T in the Treatment of R/R B-Cell Hematologic Malignancies

for Hematologic Malignancies

Sponsor: YANRU WANG

Sex: All·Age: 18 - 70

Code: NCT07316907·Phase 1

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

for Amyloidosis

1 site in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07285044·Phase 2

Apply to this trial

Patient Interest in an Integrative Oncology Program at USC Norris Cancer Center: A Single-Institution Needs Assessment

for Hematopoietic and Lymphatic System Neoplasm

1 site in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT07306338

Apply to this trial

Impact of Physician Behavior on Cancer Distress

for Hematopoietic and Lymphatic System Neoplasm

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07325006

Apply to this trial

Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation

for Hematologic Malignancies

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 75

Code: NCT07162038·Phase 1

Apply to this trial

Voices: Messages of Wisdom and Hope in the Face of Illness

for Hematopoietic and Lymphatic System Neoplasm

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07381179

Apply to this trial

HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCT

for Hematologic Malignancy

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06731504·EARLY_Phase 1

Apply to this trial

Hematologic malignancy clinical trials — common questions

Are hematologic malignancy clinical trials free to join?

Yes. Participating in a hematologic malignancy clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a hematologic malignancy clinical trial?

Each hematologic malignancy study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a hematologic malignancy trial near me?

Use the location controls above. We'll show recruiting hematologic malignancy trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many hematologic malignancy trials are recruiting right now?

We're currently tracking roughly 214 recruiting hematologic malignancy trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Hematologic malignancy trials by city

Duarte, CA Jacksonville, FL Birmingham, AL Columbus, OH Seattle, WA Los Angeles, CA Boston, MA Portland, OR Ann Arbor, MI Aurora, CO Chicago, IL Detroit, MI

Related specialties

Oncology Blood cancer