As of July 2026, 233 paid clinical trials are recruiting in Worcester, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Worcester offers studies at sites including University of Massachusetts Chan Medical School for conditions such as Schizophrenia, Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Atrial Fibrillation. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Worcester has approximately 233 recruiting research studies across a wide range of therapeutic areas. Massachusetts is a global epicenter of biomedical research, anchored by Harvard-affiliated hospitals (MGH, Brigham and Women's, Dana-Farber), Boston Children's Hospital, and the Kendall Square biotech corridor in Cambridge.
Researchers run research studies in Worcester, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Massachusetts Chan Medical School | Immune Thrombocytopenic Purpura (ITP), Rheumatoid Arthritis, Acute Stress Reaction | 33 |
| UMass Memorial Medical Center - University Campus | Stage IV Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, B Acute Lymphoblastic Leukemia | 30 |
| UMass Memorial Medical Center | Intracerebral Hemorrhage, Acute Kidney Injury, Atrial Fibrillation | 23 |
| UMass Chan Medical School | Atrial Fibrillation, AML With Mutated NPM1, ASCVD | 19 |
| University of Massachusetts Memorial Medical Center | Pregnancy, High Risk, B-cell Malignancy, Becker Muscular Dystrophy | 16 |
| University of Massachusetts | Abdominal Aortic Aneurysm, Acute Ischemic Stroke, Acute Lymphoblastic Leukemia (ALL) | 14 |
| University of Massachusetts Medical School | Multiple Sclerosis, Alcohol; Use, Problem, Amyotrophic Lateral Sclerosis | 9 |
| Vitalix Clinical | Major Depressive Disorder, Alzheimer Disease, Post Traumatic Stress Disorder | 4 |
| UMass Memorial Health | Clostridium Difficile Infection, Fecal Microbiota Transplantation, Fragile X Syndrome | 3 |
| University of Massachusetts Medical Center | Aortic Valve Disease, Aortic Valve Stenosis, COACH | 3 |
| GSK Investigational Site | Multiple Myeloma, Neoplasms, Head and Neck, Newly Diagnosed Multiple Myeloma | 2 |
| Local Institution - 0059 | Schizophrenia, Autism-Related Irritability | 2 |
| Reliant Medical Group | Asthma, Asthma Attack, Asthma Exacerbations | 2 |
| UMass Memorial Hospital | Genetic Predisposition to Disease, Genetics Disease, Genetics/Birth Defects | 2 |
| UMass/Shields | Esophageal Cancer, Gastric Cancer (GC), Gastroesophageal Junction | 2 |
| UMassMemorial Health Care | Fatigue, Shift Work Type Circadian Rhythm Sleep Disorder, Wellness, Psychological | 2 |
| University of Massachusetts Memorial Health | Lupus Nephritis, Neuropsychiatric Systemic Lupus Erythematosus, Postpartum Hypertension | 2 |
| University of Massachusetts Memorial Health Care | Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation | 2 |
| University of Massachusetts Worcester | GIST, Triple Negative Breast Cancer | 2 |
| Central Massachusetts Health Center | Alcohol-Related Disorders, Contraception, Maternal Health | 1 |
| Clinical Research | Immunoglobulin A Nephropathy | 1 |
| Clinical Study Site | Non-Small Cell Lung Cancer | 1 |
| Decentralized | Adherence, Medication, Anticoagulants and Bleeding Disorders, Atrial Fibrillation | 1 |
| Family Health Center of Worcester | Depression, Diabetes, Hyperlipidemias | 1 |
| Investigative | Hidradenitis Suppurativa | 1 |
Recruiting trials in Worcester grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Massachusetts are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Massachusetts trials follow additional state privacy requirements enforced under 201 CMR 17.00 and oversight from the Massachusetts Department of Public Health.
Hipa.ai aggregates every recruiting study in Worcester from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 233 recruiting clinical trials in Worcester, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Worcester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Worcester include Schizophrenia (6), Stage IV Lung Cancer AJCC v8 (5), Acute Myeloid Leukemia (4), Atrial Fibrillation (4), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Worcester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Worcester include University of Massachusetts Chan Medical School, UMass Memorial Medical Center - University Campus, UMass Memorial Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Worcester are Cancer & tumors (62), Neurology & pain (18), Mental health & behavior (14). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.