Rhabdomyosarcoma Clinical Trials

Recruiting rhabdomyosarcoma studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat rhabdomyosarcoma. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting rhabdomyosarcoma studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting rhabdomyosarcoma trials

Within

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

for Pediatric Solid Tumors

1 site in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT07514819

my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults

for Sarcoma

1 site in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 15 - 24

Code: NCT07516353

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

for Rhabdomyosarcoma

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT07466316·Phase 3

Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors

for Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)

Sponsor: Sun Yat-sen University

Sex: All·Age: 2 - 18

Code: NCT07584499·Phase 1

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Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

for Adenocarcinoma

1 site in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT07628634·EARLY_Phase 1

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Tumor-Lymph Node Mapping

for Pediatric Solid Tumors

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 1 Month - 17

Code: NCT07054944

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Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors

for Solid Tumor (Excluding CNS)

1 site in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 21+

Code: NCT07224568·Phase 1

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

for Neuroblastoma

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 6 Months - 25

Code: NCT06625190·Phase 1, Phase 2

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A Clinical Study on the Efficacy and Safety of All-trans Retinoic Acid Combined With VAC Regimen in the Treatment of Intermediate-to-high-risk Rhabdomyosarcoma

for Rhabdomyosarcoma

Sponsor: Fudan University

Sex: All·Age: 14 - 60

Code: NCT07355855·Phase 2

Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)

for Rhabdomyosarcoma

2 sites in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 1 - 23

Code: NCT07172958·Phase 1

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Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

for Solid Tumor (Excluding CNS)

1 site in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 1 - 26

Code: NCT07148050·Phase 1

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Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

for Somatostatin Receptor Positive

2 sites incl. Philadelphia

Sponsor: ITM Solucin GmbH

Sex: All·Age: 24 Months - 18

Code: NCT06441331·Phase 1

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FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma

for Rhabdomyosarcoma

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 3 - 39

Code: NCT06865664·Phase 1

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Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

for Hepatoblastoma

1 site in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 21

Code: NCT06198296·Phase 1

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Exploratory Study of Personalized mRNA Vaccine in Patients With Refractory Rhabdomyosarcoma

for Rhabdomyosarcoma

Sponsor: Xinxin Zhang

Sex: All·Age: 6+

Code: NCT06932861·EARLY_Phase 1

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

for Metastatic Sarcoma

3 sites incl. Washington D.C.

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: Up to 39

Code: NCT06796543

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Identification of Specific Molecular Signatures in Pediatric, Adolescent, and Young Adult Rhabdomyosarcoma Through Spatial Proteome Analysis Using Mass Spectrometry

for Rhabdomyosarcoma

Sponsor: Lille University

Sex: All·Age: 0 - 25

Code: NCT06924463

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Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models

for Neuroblastoma

Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Sex: All·Age: 0 - 18

Code: NCT06822842

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

for Sarcoma

3 sites in Boston

Sponsor: David S Shulman, MD

Sex: All·Age: 12 - 49

Code: NCT06709495·Phase 1, Phase 2

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Multi-cohort, Single-arm Phase II Study of Albumin-paclitaxel, Ifosfamide, and Cisplatin in the Treatment of Rare Advanced Tumors

for Paget Disease, Extramammary

Sponsor: Fudan University

Sex: All·Age: 18+

Code: NCT06684327·Phase 2

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Ivonescimab in the Treatment of Multiple Advanced Tumors

for Pheochromocytoma/Paraganglioma

Sponsor: Fudan University

Sex: All·Age: 18+

Code: NCT06683846·Phase 2

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Analyzing Engagement Trends in Rhabdomyosarcoma Clinical Trials

for Rhabdomyosarcoma

1 site in San Francisco

Sponsor: Power Life Sciences Inc.

Sex: All·Age: 18+

Code: NCT06029465

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

21 sites incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2

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Effectiveness of Pucotenlimab Combined With Standard Chemotherapy Regimen

for Rhabdomyosarcoma

Sponsor: Sun Yat-sen University

Sex: All·Age: 1 - 18

Code: NCT06456892·Phase 1, Phase 2

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Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

for Liver Cancer

1 site in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 - 21

Code: NCT04715191·Phase 1

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Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

for Rhabdomyosarcoma

3 sites incl. Palo Alto

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 22

Code: NCT06023641·Phase 2

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Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)

for Ewing Sarcoma

Sponsor: University Hospital Tuebingen

Sex: All·Age: 2 - 40

Code: NCT06094101·Phase 1, Phase 2

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VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

for Solid Tumor

7 sites incl. Chicago

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 6 Months - 30

Code: NCT04796012·Phase 1, Phase 2

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B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

for Pediatric Solid Tumor

1 site in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04897321·Phase 1

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HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

for Sarcoma

1 site in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 1 - 25

Code: NCT04995003·Phase 1

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FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma

for Rhabdomyosarcoma

Sponsor: University of Birmingham

Sex: All·Age: All ages

Code: NCT04625907·Phase 1, Phase 2

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Molecular-Functional Imaging of Hypoxia in Childhood Sarcomas

for Rhabdomyosarcoma

Sponsor: The Hospital for Sick Children

Sex: All·Age: 6 - 18

Code: NCT03054792·Phase 1

Familial Investigations of Childhood Cancer Predisposition

for Acute Leukemia

1 site in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT03050268

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Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies

for Ewing Sarcoma

1 site in Valhalla

Sponsor: New York Medical College

Sex: All·Age: 1 - 30

Code: NCT04308330·Phase 1

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A Prospective Clinical Cohort Study on Stratified Treatment of Rhabdomyosarcoma Based on Risk Factors.

for Rhabdomyosarcoma

Sponsor: Yizhuo Zhang

Sex: All·Age: 0 - 18

Code: NCT06836492·Phase 3

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Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

for Acute Myeloid Leukemia

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 7 Months - 21

Code: NCT02508038·Phase 1

Apply to this trial

Rhabdomyosarcoma clinical trials — common questions

Are rhabdomyosarcoma clinical trials free to join?

Yes. Participating in a rhabdomyosarcoma clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a rhabdomyosarcoma clinical trial?

Each rhabdomyosarcoma study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a rhabdomyosarcoma trial near me?

Use the location controls above. We'll show recruiting rhabdomyosarcoma trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many rhabdomyosarcoma trials are recruiting right now?

We're currently tracking roughly 20 recruiting rhabdomyosarcoma trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Rhabdomyosarcoma trials by city

Boston, MA Seattle, WA Birmingham, AL Chicago, IL Gainesville, FL Madison, WI Orange, CA Palo Alto, CA San Francisco, CA

Related specialties

Oncology Pediatric oncology