Solid tumor Clinical Trials

Recruiting solid tumor studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat solid tumor. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting solid tumor studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting solid tumor trials

Within

BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion

for Metastatic Biliary Tract Carcinoma

1 site in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07594626·Phase 1, Phase 2

Novel mRNA-LNP-Based Intratumoral Immunotherapy in Patients With Advanced Malignant Solid Tumors

for Advanced Solid Tumor

1 site in Richmond

Sponsor: IntraAb, Inc.

Sex: All·Age: 18+

Code: NCT07587879·Phase 1, Phase 2

A Multicenter Randomized Open-Label Trial Evaluating MRD-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

for NSCLC (Advanced Non-small Cell Lung Cancer)

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07689812

Adoption of Audio Recording in the Outpatient Supportive Care Center

for Advanced Malignant Solid Neoplasm

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04871477

Probiotic Supplementation During Cytotoxic Chemotherapy for Solid Tumor Malignancies

for Solid Tumor, Adult

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06772090

Wearable Data for Personalized Prognostication in Cancer: A Registry Protocol

for Hematopoietic Neoplasm

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07691008

Pharmacokinetics Study of Larotinib in Subjects With Impaired Hepatic Function

for Esophageal Cancer

Sponsor: Sunshine Lake Pharma Co., Ltd.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT05048368·Phase 1

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

2 sites incl. Boston

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07137416·Phase 1

Apply to this trial

Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation

for Graft Versus Host Disease

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 7+

Code: NCT07235501

Apply to this trial

Ivermectin Combined With Immune Checkpoint Inhibition in Cancer (ICONIC)

for Solid Tumor, Adult

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT07487805·Phase 2

Evaluating the Effects of Propionate and Butyrate Supplementation on the Intestinal Health of Healthy Volunteers

for Graft Versus Host Disease

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07611370·Phase 1

A Study of Risvutatug Rezetecan in Combination With Ivonescimab in Participants With Advanced Solid Tumors (EMBOLD PanTumour-103)

for Solid Tumors

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07602855·Phase 1, Phase 2

A Wearable Biosensor Patch for Non-Invasive Monitoring for Patients Undergoing Abdominal or Chest Surgery

for Hematopoietic and Lymphatic System Neoplasm

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07612085

Olaparib in the Treatment of BRCA1/2 Unmutated and BRCA1 Promoter Methylated Recurrent and Metastatic Triple-negative Breast Cancer

for Solid Tumor

Sponsor: Hebei Medical University Fourth Hospital

Sex: Female·Age: 18 - 70

Code: NCT05522491·Phase 2

Virtual Reality Viewing of Unaltered Streetscape Versus Digitally Manipulated Opposite Streetscape to Assess Psychosocial Response in Participants

for Hematopoietic and Lymphatic System Neoplasm

1 site in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07216534

Apply to this trial

A Spiritual Health Intervention (PATH) for Improving Spiritual, Religious and Emotional Distress in Cancer Patients

for Hematopoietic and Lymphatic System Neoplasm

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07545291

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

for Clinical Stage III Cutaneous Melanoma AJCC v8

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07576725·Phase 2

Cannabis Gummy for the Improvement of Sleep and Quality of Life in Patients With Cancer, Pillow Trial

for Hematopoietic and Lymphatic System Neoplasm

1 site in Columbus

Sponsor: Theodore Brasky PhD

Sex: All·Age: 18+

Code: NCT07658677·Phase 1, Phase 2

UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations

for Solid Tumor

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06895681

A Study to Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors

for Advanced Solid Tumors

2 sites incl. Boston

Sponsor: LigaChem Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07460375·Phase 1, Phase 2

Allogeneic NK Cell Therapy Combined With Standard Maintenance Treatment in Advanced Solid Tumors

for NSCLC (Advanced Non-small Cell Lung Cancer)

Sponsor: BOE Technology Group Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07551778·Phase 1, Phase 2

XTX501 in Patients With Metastatic Non-Small Cell Lung Cancer and Advanced Solid Tumors

for Metastatic NSCLC - Non-Small Cell Lung Cancer

Sponsor: Xilio Development, Inc.

Sex: All·Age: 18+

Code: NCT07688577·Phase 1, Phase 2

A Study to Evaluate the Safety and Antitumor Activity of GS-1206 in Adults With Solid Tumors

for Solid Tumor

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT07703878·Phase 1

Improving Processes of Cancer Care Delivery at a Comprehensive Cancer Center

for Metastatic Malignant Solid Neoplasm

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05095948

A Phase I Study to Evaluate the Safety,Pharmacokinetics,Pharmacodynamics,and Efficacy of TJ037130 in Adult Participants With Advanced Solid Tumors

for Solid Tumor

Sponsor: TJ Biopharma Co., Ltd.

Sex: All·Age: 18+

Code: NCT07715747·Phase 1

Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids

for Hematopoietic and Lymphatic System Neoplasm

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 18 - 75

Code: NCT06827054·Phase 2

HMPL-A830 in Solid Tumors

for Solid Tumor, Adult

Sponsor: Hutchmed

Sex: All·Age: 18+

Code: NCT07718581·Phase 1, Phase 2

First-in-Human Trial of DS1025a in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT07681882·Phase 1

A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial

for Malignant Solid Neoplasm

2 sites incl. Bellingham

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT06771739

OVV-01 Intravenous and Intratumoral Injection Combined With AK112 for the Treatment of Advanced Solid Tumors

for Advanced Solid Tumors

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Sex: All·Age: 18+

Code: NCT07650825·Phase 1

Imaging Study of [89Zr]DFO-YS5 for Cancer Detection

for Bladder Cancer

1 site in San Francisco

Sponsor: Robert Flavell, MD, PhD

Sex: All·Age: 18+

Code: NCT07664397·Phase 1

Transcranial Direct Current Stimulation for the Treatment of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors

for Chemotherapy-Induced Peripheral Neuropathy

1 site in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18 - 85

Code: NCT07673614

Bicycle Continued Access Protocol (BiCAP) for Participants Receiving a Bicycle Investigational Product

for Advanced Solid Tumors

Sponsor: BicycleTx Limited

Sex: All·Age: 18+

Code: NCT07681674·Phase 2

A Study of FG-B901 Monotherapy or Combination With Chemotherapy in Advanced or Metastatic Solid Tumors

for Solid Tumor

Sponsor: FutureGen Biopharmaceutical (Beijing) Co., Ltd

Sex: All·Age: 18 - 75

Code: NCT07623707·Phase 1, Phase 2

Study of LT-010391 in Participants With KRAS G12D-Mutant Solid Tumors

for Non-small Cell Lung Cancer (NSCLC)

Sponsor: Leadingtac Pharmaceutical (Shaoxing) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07624214·Phase 1

A Study of CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101)

for Advanced Solid Tumor

4 sites incl. Durham

Sponsor: Clasp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07650357·Phase 1

A Clinical Study of SHR-4685 on Safety, Tolerability and Pharmacokinetics in Participants With Solid Tumors

for Solid Tumor

Sponsor: Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07676903·Phase 1

A Study of SI-B036 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors

for Gastrointestinal Tumor

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07678970·Phase 1

A Phase Ib/II Study of BM230 in Combination With PD-1 Inhibitor for HER2-related Advanced Solid Tumors

for Solid Tumor

Sponsor: Suzhou Biomissile Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT07698587·Phase 1, Phase 2

HSK41959 With Standard Therapy in Solid Tumors With MTAP Deletion

for Non-Small Cell Lung Cancer

Sponsor: Haisco Pharmaceutical Group Co., Ltd.

Sex: All·Age: 18+

Code: NCT07699757·Phase 1

Safety and Efficacy of Canagliflozin in Patients With Locally Advanced or Advanced Solid Cancer

for Solid Tumor

Sponsor: West China Hospital

Sex: All·Age: 18 - 80

Code: NCT07703163·Phase 1

A Phase Ia/Ib Study of HW221043 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

Sponsor: Hubei Bio-Pharmaceutical Industrial Technological Institute Inc.

Sex: All·Age: 18+

Code: NCT07719920·Phase 1

NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors

for Very Rare Tumors

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 Month - 120

Code: NCT07489378

Apply to this trial

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

for Extensive-Stage Small Cell Lung Cancer

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT07509034·Phase 1

A Multicenter, Open-label, Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics (PK), and Immunogenicity of the Combination Therapy of SYS6026 in the Treatment of Advanced Solid Tumors

for Solid Tumor

Sponsor: CSPC Megalith Biopharmaceutical Co.,Ltd.

Sex: All·Age: 18+

Code: NCT07684261

Study of D3L-002 in Subjects With Advanced Solid Tumors

for Advanced Solid Tumor

Sponsor: D3 Bio (Wuxi) Co., Ltd

Sex: All·Age: 18+

Code: NCT07667842·Phase 1

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

for Solid Tumors

18 sites incl. San Francisco

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07492680·Phase 2

Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas

for Digestive System Neuroendocrine Neoplasm

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 18+

Code: NCT06202066·Phase 2

Apply to this trial

A Study to Evaluate the Safety, Tolerability, PK and Efficacy of Hemay5087 in Patients With Advanced Solid Tumors

for Solid Tumors

Sponsor: Ganzhou Hemay Pharmaceutical Co., Ltd

Sex: All·Age: 18 - 75

Code: NCT07624864·Phase 1

First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors

for Advanced Solid Tumors

5 sites incl. Duarte

Sponsor: VelaVigo Bio Inc

Sex: All·Age: 18+

Code: NCT07700160·Phase 1, Phase 2

Evaluation of ICP-B208 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sponsor: Beijing InnoCare Pharma Tech Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07617493·Phase 1, Phase 2

Apply to this trial

IL-15 Enhanced NK Cell Therapy for Solid Tumors

for Solid Tumors

Sponsor: Genovn Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18 - 70

Code: NCT07621471·EARLY_Phase 1

Gotistobart Long Term Extension (LTE) Study

for Advanced Solid Tumor

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT07659379·Phase 3

Magnetic Resonance-Guided Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Tumors, ONE SHOT Trial

for Metastatic Malignant Solid Neoplasm

1 site in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07671768

Study of ISM5939 in Patients With Advanced and/or Metastatic Solid Tumors

for Advanced Solid Tumor

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 18+

Code: NCT06724042·Phase 1

CD70.CAR for CD70+ Lymphoma, Myeloma and Solid Tumors

for Lymphoma

2 sites in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 0 - 75

Code: NCT07297160·Phase 1

A Clinical Study of ZL-85FA Tablets

for Advanced Solid Tumor

Sponsor: Chengdu Zenitar Biomedical Technology Co., Ltd

Sex: All·Age: 18 - 75

Code: NCT07339748·Phase 1, Phase 2

A Clinical Study GK01 Cell Injection in Subjects With Advanced Solid Tumors.

for Advanced Solid Tumors

Sponsor: Beijing Geekgene Technology Co., LTD

Sex: All·Age: 18 - 70

Code: NCT07412665·EARLY_Phase 1

A Study of Freeze-Dried Miracle Fruit (MiraBurst) on Participants Receiving Cancer Treatment

for Dysgeusia

1 site in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07419581

SKB565 for Injection in Advanced Solid Tumors

for Advanced Solid Tumors

Sponsor: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07545265·Phase 1, Phase 2

Solid tumor clinical trials — common questions

Are solid tumor clinical trials free to join?

Yes. Participating in a solid tumor clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a solid tumor clinical trial?

Each solid tumor study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a solid tumor trial near me?

Use the location controls above. We'll show recruiting solid tumor trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many solid tumor trials are recruiting right now?

We're currently tracking roughly 495 recruiting solid tumor trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Solid tumor trials by city

Los Angeles, CA Duarte, CA Birmingham, AL San Francisco, CA Jacksonville, FL Boston, MA Denver, CO Chicago, IL Columbus, OH Portland, OR La Jolla, CA Aurora, CO

Related specialties

Oncology