Solid tumor Clinical Trials

Recruiting solid tumor studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat solid tumor. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting solid tumor studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting solid tumor trials

Within

Symptom Management to Improve Completion of Patient-reported Outcome Measures

for Malignant Solid Neoplasm

1 site in Detroit

Sponsor: Henry Ford Health System

Sex: All·Age: 18+

Code: NCT07723495

Targeting CD276 (B7-H3) Positive Solid Tumors by 4SCAR-276

for Solid Tumor

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 1 - 75

Code: NCT04432649·Phase 1, Phase 2

Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease

for Chronic Graft Versus Host Disease

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07733141

Novel mRNA-LNP-Based Intratumoral Immunotherapy in Patients With Advanced Malignant Solid Tumors

for Advanced Solid Tumor

1 site in Richmond

Sponsor: IntraAb, Inc.

Sex: All·Age: 18+

Code: NCT07587879·Phase 1, Phase 2

Study on GD2 Positive Solid Tumors by 4SCAR-GD2

for Solid Tumor

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 1 - 65

Code: NCT02992210·Phase 1, Phase 2

GD2/PSMA Bi-specific CAR-T Cell Therapy

for Solid Tumor

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 1 - 75

Code: NCT05437315·Phase 1, Phase 2

A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

for NSCLC (Advanced Non-small Cell Lung Cancer)

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07689812

Adoption of Audio Recording in the Outpatient Supportive Care Center

for Advanced Malignant Solid Neoplasm

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04871477

Study of ISM5939 in Patients With Advanced and/or Metastatic Solid Tumors

for Advanced Solid Tumor

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 18+

Code: NCT06724042·Phase 1

Probiotic Supplementation During Cytotoxic Chemotherapy for Solid Tumor Malignancies

for Solid Tumor, Adult

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06772090

A Study of TIL in Advanced Solid Tumors (CZ)

for Solid Tumor, Adult

Sponsor: Shanghai Juncell Therapeutics

Sex: All·Age: 18 - 70

Code: NCT07294872·Phase 1

Magnetic Resonance-Guided Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Tumors, ONE SHOT Trial

for Metastatic Malignant Solid Neoplasm

1 site in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07671768

Wearable Data for Personalized Prognostication in Cancer: A Registry Protocol

for Hematopoietic Neoplasm

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07691008

Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital

for Breast Carcinoma

1 site in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07606287

Tele-HOPE: A Telehealth Pharmacist Opioid Patient Education Pilot Study

for Hematopoietic and Lymphatic System Neoplasm

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07737314

Pharmacokinetics Study of Larotinib in Subjects With Impaired Hepatic Function

for Esophageal Cancer

Sponsor: Sunshine Lake Pharma Co., Ltd.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT05048368·Phase 1

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

2 sites incl. Boston

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07137416·Phase 1

Apply to this trial

Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation

for Graft Versus Host Disease

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 7+

Code: NCT07235501

A Study of Strengthening Teen Brain Resilience Using Music During Cancer Treatment

for Childhood Hematopoietic and Lymphatic System Neoplasm

1 site in Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 12 - 17

Code: NCT07729384

A Study of DS-3939a in Participants With Solid Tumors

for Solid Tumor

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT07739966·Phase 1, Phase 2

An Artificial Intelligence-Powered Supportive Care Chatbot to Address the Supportive Care Needs of Young Adult Cancer Survivors

for Hematopoietic and Lymphatic System Neoplasm

1 site in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18 - 39

Code: NCT07772596

Ivermectin Combined With Immune Checkpoint Inhibition in Cancer (ICONIC)

for Solid Tumor, Adult

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT07487805·Phase 2

SKB565 for Injection in Advanced Solid Tumors

for Advanced Solid Tumors

Sponsor: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07545265·Phase 1, Phase 2

Evaluating the Effects of Propionate and Butyrate Supplementation on the Intestinal Health of Healthy Volunteers

for Graft Versus Host Disease

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07611370·Phase 1

Validation of the G8 Screening Tool for Prognostic Assessment of Frailty and Early Mortality in Elderly Individuals With Cancer: Prospective Cohort Study in Brazil

for Solid Tumor

Sponsor: Latin American Cooperative Oncology Group

Sex: All·Age: 70+

Code: NCT07773285

A Study of SI-B036 in Patients With Locally Advanced or Metastatic Gynecological Tumors and Other Solid Tumors

for Gynecological Tumors

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07778862·Phase 1

A Study of BL-M08D in Patients With Locally Advanced or Metastatic Digestive Tract Tumors and Other Solid Tumors

for Gastrointestinal Tumors

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07780318·Phase 1, Phase 2

NK Cell Injection for Advanced Solid Tumors

for Advanced Solid Tumors

Sponsor: BOE Technology Group Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07784777·Phase 1

A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010)

for Advanced Solid Tumors

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07785609·Phase 2

A Study of BL-M08D1 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

for Head and Neck Squamous Cell Carcinomas

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07788950·Phase 2

A Study of BL-M08D1 in Patients With Recurrent or Metastatic Gynecological Malignancies and Other Solid Tumors

for Gynecological Tumors

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: Female·Age: 18 - 75

Code: NCT07793825·Phase 1, Phase 2

Pedi-STAR: Surface Target Antibody-drug Conjugate (ADC) Antigen Expression in Relapsed/Refractory Pediatric Solid and CNS Tumors

for CNS Tumor

2 sites in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 30

Code: NCT07793994

A Clinical Trial of MK-2010 Alone and With Other Treatments in Participants With Advanced Solid Tumors (MK-2010-002)

for Malignant Neoplam

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07793942·Phase 2

An Open-label Study of SG1827 Combined With Anti-PD-1/PD-L1 Antibody and Bevacizumab in Patients With Advanced Solid Tumors

for Advanced Solid Tumors

Sponsor: Hangzhou Sumgen Biotech Co., Ltd.

Sex: All·Age: 18+

Code: NCT07774611·Phase 1, Phase 2

Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids

for Hematopoietic and Lymphatic System Neoplasm

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 18 - 75

Code: NCT06827054·Phase 2

A Study of Risvutatug Rezetecan in Combination With Ivonescimab in Participants With Advanced Solid Tumors (EMBOLD PanTumour-103)

for Solid Tumors

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07602855·Phase 1, Phase 2

A First-in-Human Study Investigating BG-85738 Alone or in Combination With Other Antitumor Agents in Patients With Advanced or Metastatic Solid Tumors With Rat Sarcoma Virus (RAS) Mutations

for RAS Mutation

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07746141·Phase 1

Testing an Educational Program to Improve Goals of Care Conversations Between Patients and Their Care Teams

for Malignant Solid Neoplasm

1 site in Little Rock

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07278739

Apply to this trial

NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors

for Very Rare Tumors

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 Month - 120

Code: NCT07489378

Apply to this trial

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

for Extensive-Stage Small Cell Lung Cancer

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT07509034·Phase 1

A Wearable Biosensor Patch for Non-Invasive Monitoring for Patients Undergoing Abdominal or Chest Surgery

for Hematopoietic and Lymphatic System Neoplasm

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07612085

Olaparib in the Treatment of BRCA1/2 Unmutated and BRCA1 Promoter Methylated Recurrent and Metastatic Triple-negative Breast Cancer

for Solid Tumor

Sponsor: Hebei Medical University Fourth Hospital

Sex: Female·Age: 18 - 70

Code: NCT05522491·Phase 2

Community-Based Exercise and Nutrition Training and Education Program for Cancer Survivors

for Hematopoietic and Lymphatic System Neoplasm

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 18+

Code: NCT06565260

Apply to this trial

A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial

for Malignant Solid Neoplasm

2 sites incl. Bellingham

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT06771739

Virtual Reality Viewing of Unaltered Streetscape Versus Digitally Manipulated Opposite Streetscape to Assess Psychosocial Response in Participants

for Hematopoietic and Lymphatic System Neoplasm

1 site in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07216534

Apply to this trial

A Spiritual Health Intervention (PATH) for Improving Spiritual, Religious and Emotional Distress in Cancer Patients

for Hematopoietic and Lymphatic System Neoplasm

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07545291

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

for Clinical Stage III Cutaneous Melanoma AJCC v8

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT07576725·Phase 2

Cannabis Gummy for the Improvement of Sleep and Quality of Life in Patients With Cancer, Pillow Trial

for Hematopoietic and Lymphatic System Neoplasm

1 site in Columbus

Sponsor: Theodore Brasky PhD

Sex: All·Age: 18+

Code: NCT07658677·Phase 1, Phase 2

Phase I/II Clinical Trials of SHR-8203 Injection in Participants With Advanced Solid Tumors

for Solid Tumors

Sponsor: Beijing Suncadia Pharmaceuticals Co., Ltd

Sex: All·Age: 18 - 75

Code: NCT07769242·Phase 1, Phase 2

UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations

for Solid Tumor

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06895681

A Study to Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors

for Advanced Solid Tumors

4 sites incl. Boston

Sponsor: LigaChem Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07460375·Phase 1, Phase 2

Apply to this trial

Allogeneic NK Cell Therapy Combined With Standard Maintenance Treatment in Advanced Solid Tumors

for NSCLC (Advanced Non-small Cell Lung Cancer)

Sponsor: BOE Technology Group Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07551778·Phase 1, Phase 2

XTX501 in Patients With Metastatic Non-Small Cell Lung Cancer and Advanced Solid Tumors

for Metastatic NSCLC - Non-Small Cell Lung Cancer

Sponsor: Xilio Development, Inc.

Sex: All·Age: 18+

Code: NCT07688577·Phase 1, Phase 2

Evaluate the Diagnostic Efficacy and Safety of INR 202 PET/CT Imaging in Participants With Advanced Solid Tumors

for Solid Tumors

Sponsor: Shanghai Zhongshan Hospital

Sex: All·Age: 18+

Code: NCT07727317

A Study of IOV-5001 in Adults With Advanced Solid Tumors

for Advanced Solid Tumors

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT07743723·Phase 1, Phase 2

A Study of SI-B036 in Patients With Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors

for Breast Cancer

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07753226·Phase 1

A Clinical Study to Evaluate Single-agent Therapy of BR113 for Injection in Patients With Advanced Solid Tumors

for Advanced Solid Tumors

Sponsor: BioRay Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT07753590·Phase 1

A Study of SI-B036 in Patients With Locally Advanced or Metastatic Head and Neck Tumors and Other Solid Tumors

for Head and Neck Tumors

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07763639·Phase 1

A Study of BL-ARC002 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors

for Gastrointestinal Tumors

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT07763652·Phase 1

A Study of BL-M09D1 in Patients With Locally Advanced or Metastatic Gynecological Malignancies and Other Solid Tumors

for Gynecological Malignancies

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: Female·Age: 18 - 75

Code: NCT07769229·Phase 2

New trials in Los Angeles, CA?

Pick a condition and we'll email you once a week when a new study starts recruiting in Los Angeles, CA. Unsubscribe anytime.

Solid tumor clinical trials — common questions

Are solid tumor clinical trials free to join?

Yes. Participating in a solid tumor clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a solid tumor clinical trial?

Each solid tumor study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a solid tumor trial near me?

Use the location controls above. We'll show recruiting solid tumor trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many solid tumor trials are recruiting right now?

We're currently tracking roughly 495 recruiting solid tumor trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Solid tumor trials by city

Los Angeles, CA Duarte, CA Birmingham, AL San Francisco, CA Jacksonville, FL Boston, MA Denver, CO Chicago, IL Columbus, OH Portland, OR La Jolla, CA Aurora, CO

Related specialties

Oncology