Non-small cell lung cancer (NSCLC) Clinical Trials in Baltimore, MD
As of August 2026, 37 paid clinical trials are recruiting for Non-small cell lung cancer (NSCLC) in Baltimore, Maryland. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Baltimore
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
38 clinical trials for Non-small cell lung cancer (NSCLC)
·Clear filters·A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
GEMINI-NSCLC: NSCLC Biomarker Study
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors
A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)
A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)
Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer
Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer
First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
DK222 Study at Hopkins
Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients
A Study Evaluating Neoadjuvant Chemoimmunotherapy With Immunosensitizing Radiation for Borderline Resectable Non-Small Cell Lung Cancer
KRAS-Targeted Vaccine With Chemoimmunotherapy, Nivolumab and Ipilimumab for Patients With NSCLC
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations
Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
Top Research Study Locations in Baltimore
Researchers run research studies in Baltimore, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Johns Hopkins University | Cystic Fibrosis, Pancreatic Ductal Adenocarcinoma (PDAC), Prostate Cancer | 189 |
| Johns Hopkins Hospital | Barrett Esophagus, Bladder Cancer, Urothelial Cancer | 120 |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, B Acute Lymphoblastic Leukemia | 63 |
| University of Maryland | Acute Kidney Injury, Carcinoma, Non-Small-Cell Lung, Multiple Myeloma | 58 |
| University of Maryland Medical Center | Subarachnoid Hemorrhage, Acute Kidney Injury, Cardiomyopathies | 51 |
| Sinai Hospital of Baltimore | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, B Acute Lymphoblastic Leukemia | 49 |
| Johns Hopkins University School of Medicine | Alcohol Use Disorder, Amputation, Traumatic, Chronic Low-back Pain | 44 |
| University of Maryland/Greenebaum Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia | 43 |
| Johns Hopkins | Primary Immune Deficiency Disorder, Chronic Obstructive Pulmonary Disease (COPD), Atrial Fibrillation | 38 |
| Kennedy Krieger Institute | Adrenomyeloneuropathy, Autism Spectrum Disorder, Cerebral Palsy | 30 |
| Johns Hopkins School of Medicine | Alzheimer Disease, Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy | 29 |
| Johns Hopkins Bayview Medical Center | Carcinoma, Non-Small-Cell Lung, Healthy, Sleep | 26 |
| Greater Baltimore Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Amblyopia, Anatomic Stage IIIA Breast Cancer AJCC v8 | 21 |
| The Johns Hopkins Hospital | Achilles Tendon Repairs/Reconstructions, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Aortic Stenosis | 21 |
| Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD | Cognitive Impairment, Falls, Obesity | 20 |
| University of Maryland, Baltimore | Fatigue, Stroke, ADPKD (Autosomal Dominant Polycystic Kidney Disease) | 19 |
| Johns Hopkins Medicine | Achondroplasia, Acute Kidney Injury, Aging | 19 |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Breast Cancer, Kaposi Sarcoma, Lymphoma | 18 |
| University of Maryland School of Medicine | Acute-On-Chronic Liver Failure, Brain Injury, Caregiver Distress | 17 |
| John Hopkins University | Amyotrophic Lateral Sclerosis, Advanced Solid Tumors, Allogenic Transplant Patients | 16 |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Prostate Cancer, Kidney Cancer, Metastatic Castration-resistant Prostate Cancer | 16 |
| Mercy Medical Center | Breast Cancer, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 16 |
| National Institute on Drug Abuse | Normal Physiology, Alcohol Use Disorder, Substance Use Disorder | 14 |
| Maryland Proton Treatment Center | Breast Cancer, Anatomic Stage IV Breast Cancer AJCC v8, Biliary Tract Cancer | 13 |
| National Institute of Aging, Clinical Research Unit | Healthy Volunteers, Aging, Alzheimer's Disease | 13 |
Active & Upcoming Studies in Baltimore (2026)
Recruiting trials in Baltimore grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (418 active studies)
- A Study of Topical Duvelisib in Participants With Early-stage Mycosis Fungoides · Phase 1 · SecuraBio
- Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer · Phase 2 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Neurology & pain (115 active studies)
- Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea. · Phase 2 · Johns Hopkins University
- A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep · Phase 1, Phase 2 · Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Cardiovascular (73 active studies)
- Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART) · National Heart, Lung, and Blood Institute (NHLBI)
- Pulmonary Hypertension (PH) Biorepository for Translational Research · National Institutes of Health Clinical Center (CC)
Diabetes & metabolic (52 active studies)
- Integrating Free-choice Marketplace, dieTitian coacHing, cultuRally Tailored messagIng to improVE Blood Pressure · Johns Hopkins University
- Continuous Glucose Monitors (CGMs) and Readmission Rates · University of Maryland, Baltimore
Mental health & behavior (45 active studies)
- Duloxetine and aeRobic Exercise to Improve Function in VEterans With Knee Osteoarthritis (DRIVE) · Phase 2 · VA Office of Research and Development
- Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving · Phase 2, Phase 3 · Johns Hopkins University
HIV / STI (44 active studies)
- Decision Support Tool to Integrate PrEP Into Emergency Departments · Phase 1 · George Washington University
- ED Patient's Perceptions and Acceptability Toward a Novel POC HCV Viral Load Testing · Johns Hopkins University
Eye & vision (27 active studies)
- Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects · Phase 4 · University of Maryland, Baltimore
- Optic Nerve Head Strain in Non-glaucoma Subjects · EARLY_Phase 1 · Johns Hopkins University
Pediatric (22 active studies)
- Hypoxic Red Blood Cells in Sickle Cell Anemia · Hemanext
- Mobile Technology to Reduce Teen Substance Misuse · Evidence-Based Practice Institute, Seattle, WA
Vaccines (16 active studies)
- Safety and Immunogenicity of Chimeric Hemagglutinin mRNA Vaccine Candidates · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Common conditions studied in Baltimore
- Breast Cancer (22 active studies)
- Prostate Cancer (20 active studies)
- Stroke (17 active studies)
- Heart Failure (14 active studies)
- Opioid Use Disorder (14 active studies)
- Pancreatic Cancer (13 active studies)
Leading research sponsors in Baltimore
- Johns Hopkins University
- University of Maryland, Baltimore
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- National Cancer Institute (NCI)
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Baltimore?
There are approximately 1,543 recruiting clinical trials in Baltimore, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Baltimore pay participants?
Most recruiting trials in Baltimore compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Baltimore?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Baltimore?
The most common conditions under active study in Baltimore include Breast Cancer (22), Prostate Cancer (20), Stroke (17), Heart Failure (14), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Baltimore?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Baltimore on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Baltimore?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Baltimore?
Recruiting research sites in Baltimore include Johns Hopkins University, Johns Hopkins Hospital, Johns Hopkins University/Sidney Kimmel Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Baltimore right now?
The largest active categories in Baltimore are Cancer & tumors (418), Neurology & pain (115), Cardiovascular (73). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.