ENT Clinical Trials in Boston, MA
As of August 2026, 30 paid clinical trials are recruiting for ENT in Boston, Massachusetts. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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30 clinical trials for ENT
·Clear filters·The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
Clonal Hematopoiesis Chemotherapy and Radiation Effects Study
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer
Distance-Based Exercise to Preserve Function and Prevent Disability
PDT For Induction Therapy For Head And Neck Cancer
PD-L1 t-haNK, NAI IL-15sa and Cetuximab for Recurrent, Metastatic HNSCC
Jump: MR Simulation For Radiation Therapy Master Protocol
Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment
Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC
Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma
Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers
Improving Spatial Perception and Speech Understanding in Multitalker Mixtures
Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia
Aspiration in Acute Respiratory Failure Survivors 2
A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)
Top Research Study Locations in Boston
Researchers run research studies in Boston, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Massachusetts General Hospital | Breast Cancer, Advanced Solid Tumor, Heart Failure | 693 |
| Brigham and Women's Hospital | Obesity, Breast Cancer, Prostate Cancer | 350 |
| Dana-Farber Cancer Institute | Breast Cancer, Acute Myeloid Leukemia, Multiple Myeloma | 346 |
| Beth Israel Deaconess Medical Center | Multiple Myeloma, Lymphoma, Acute Myeloid Leukemia | 263 |
| Boston Children's Hospital | Congenital Heart Disease, Cystic Fibrosis, Sickle Cell Disease | 258 |
| Dana Farber Cancer Institute | Breast Cancer, Ovarian Cancer, Prostate Cancer | 217 |
| Tufts Medical Center | Heart Failure, Acute Myeloid Leukemia, Acute Respiratory Distress Syndrome | 113 |
| Boston Medical Center | Amblyopia, Alpha1-Antitrypsin Deficiency, Anatomic Stage II Breast Cancer AJCC v8 | 95 |
| Massachusetts General Hospital Cancer Center | Breast Cancer, Coping Skills, B Acute Lymphoblastic Leukemia | 51 |
| VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA | Chronic Obstructive Pulmonary Disease, Mild Traumatic Brain Injury, Prostate Cancer | 30 |
| Brigham & Women's Hospital | Attention, Chronic Lymphocytic Leukemia, Critical Illness | 25 |
| Boston University | Obsessive-Compulsive Disorder, Adolescent Behavior Problem, Alzheimer Disease | 24 |
| Joslin Diabetes Center | Type 1 Diabetes Mellitus, Type 1 Diabetes (T1D), T1D | 22 |
| Mass General Brigham | Heart Failure, Heart Failure With Preserved Ejection Fraction, Advanced Solid Tumors | 22 |
| Northeastern University | Cognitive Change, Autism Spectrum Disorder (ASD), Healthy | 22 |
| Massachusetts Eye and Ear | Cone Rod Dystrophy, Glaucoma, Juvenile Macular Degeneration | 17 |
| Ophthalmic Consultants of Boston | Neovascular Age-related Macular Degeneration, Macular Edema Secondary to Inflammation, Age-Related Macular Degeneration | 13 |
| Adams Clinical Boston | Depressive Disorder, Major, Major Depressive Disorder, Alcohol Use Disorder | 12 |
| Brigham and Womens Hospital | Advanced Prostate Cancer, Alpha1-Antitrypsin Deficiency, Alzheimers Disease | 12 |
| Massachusetts Eye and Ear Infirmary | Laryngeal Dystonia, Stargardt Disease, Age-related Macular Degeneration | 12 |
| Clinical Trial Site | Transthyretin Amyloidosis With Cardiomyopathy, Acid Cholesteryl Ester Hydrolase Deficiency, Type 2, Acid Lipase Deficiency | 11 |
| Boston Childrens Hospital | CSTB-related Disease, Crohn's Disease, Cystic Fibrosis | 11 |
| Mass General Hospital | Biliary Tract Cancer (BTC), PDAC - Pancreatic Ductal Adenocarcinoma, AML | 11 |
| Beth Israel Deaconess Medical Center (BIDMC) | Prostate Cancer, Advanced Melanoma, Endometrial Cancer | 11 |
| Brigham and Women's Faulkner Hospital | Multimodal Analgesia, Opioid Consumption, Postoperative, Adverse Event | 8 |
Active & Upcoming Studies in Boston (2026)
Recruiting trials in Boston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (877 active studies)
- Early Intervention · Massachusetts General Hospital
- Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial) · Phase 2 · National Cancer Institute (NCI)
Neurology & pain (218 active studies)
- Mindfulness Therapy for Chronic Pain After Intimate Partner Violence · Brigham and Women's Hospital
- Computerized Decision Support to Prevent Stroke in Atrial Fibrillation · Brigham and Women's Hospital
Cardiovascular (188 active studies)
- Computerized Decision Support to Prevent Stroke in Atrial Fibrillation · Brigham and Women's Hospital
- CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock · Phase 2 · Brigham and Women's Hospital
Diabetes & metabolic (96 active studies)
- Adiposity Distribution in Acute Respiratory Failure · Maurizio F. Cereda, MD
- Creating Linked Inpatient CGM for Kids · Boston Children's Hospital
Mental health & behavior (90 active studies)
- Whole Selves User Testing and Feasibility Study · Boston University
- Clinician Practice Companion to Address Youth Substance Use · Massachusetts General Hospital
Pediatric (62 active studies)
- Clinician Practice Companion to Address Youth Substance Use · Massachusetts General Hospital
- Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary Disease · EARLY_Phase 1 · Massachusetts General Hospital
HIV / STI (33 active studies)
- Intervention to Reduce Implicit Bias in Pharmacies · Massachusetts General Hospital
- Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP · Boston Children's Hospital
Eye & vision (32 active studies)
- Glaucoma Drop Aids Part 2 · Boston Medical Center
- Study of Remimazolam for Cataract Surgery · Phase 4 · Fred E, Shapiro
Vaccines (15 active studies)
- Sauna for Long Covid · Massachusetts General Hospital
- A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Common conditions studied in Boston
- Breast Cancer (64 active studies)
- Prostate Cancer (41 active studies)
- Ovarian Cancer (36 active studies)
- Heart Failure (34 active studies)
- Acute Myeloid Leukemia (32 active studies)
- Colorectal Cancer (32 active studies)
Leading research sponsors in Boston
- Massachusetts General Hospital
- Brigham and Women's Hospital
- Boston Children's Hospital
- Dana-Farber Cancer Institute
- Beth Israel Deaconess Medical Center
Frequently asked questions
How many paid clinical trials are currently recruiting in Boston?
There are approximately 2,891 recruiting clinical trials in Boston, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Boston pay participants?
Most recruiting trials in Boston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Boston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Boston?
The most common conditions under active study in Boston include Breast Cancer (64), Prostate Cancer (41), Ovarian Cancer (36), Heart Failure (34), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Boston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Boston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Boston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Boston?
Recruiting research sites in Boston include Massachusetts General Hospital, Brigham and Women's Hospital, Dana-Farber Cancer Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Boston right now?
The largest active categories in Boston are Cancer & tumors (877), Neurology & pain (218), Cardiovascular (188). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.