Paid Clinical Trials in Newton, MA
As of August 2026, 33 paid clinical trials are recruiting in Newton, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Newton offers studies at sites including Boston Center for Memory for conditions such as Alzheimer Disease, Gastroesophageal Junction Adenocarcinoma, Narcolepsy Type 1, Alzheimers Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Newton
Trials by drug in Newton
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30 clinical trials
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)
A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)
Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices
ATEMPT 2.0: Adjuvant T-DM1 vs TH
Sacituzumab Govitecan In TNBC
BoTox Into the Sternocleidomastoid Muscles (SCM)
Outpatient Epcoritamab as 2L in NTE R/R DLBCL
Experiment 2: One Target in Many Situations
A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers
Folfox+Irinotecan+Chemort In Esophageal Cancer
ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection
A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2
A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1
A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)
Top Research Study Locations in Newton
Researchers run research studies in Newton, MA at 19 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Boston Center for Memory | Alzheimer Disease, Alzheimers Disease, AD | 8 |
| Dana-Farber Cancer Institute - Chestnut Hill | Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma, Gastroesophageal Junction Adenocarcinoma | 5 |
| Alkermes Investigational Site | Narcolepsy Type 1, Narcolepsy Type 2 | 2 |
| Newton Wellesley Hospital | Breast Cancer, HER2-positive Breast Cancer, Inflammatory Arthritis | 2 |
| Newton-Wellesley Hospital | Clostridium Difficile Infection Recurrence, Refractory Large B-cell Lymphoma, Relapsed Large B-cell Lymphoma | 2 |
| Brigham & Women's Hospital | Attention, Healthy, Vision | 1 |
| Dana Farber Cancer Institute | Metastatic Castration-resistant Prostate Cancer | 1 |
| Dana-Farber Cancer Institute -Chestnut Hill | Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases | 1 |
| Dynocardia Inc | Healthy, Hypertension | 1 |
| Mass General Cancer Center Newton-Wellesley Hospital | Non Metastatic Rectal Cancer, Rectal Cancer | 1 |
| Mass General Cancer Center at Newton-Wellesley Hospital's Vernon Cancer Center | Breast Cancer | 1 |
| Mass General at Newton Wellesley Hospital | Cancer, Caregiver Burden, Coping Skills | 1 |
| Massachusetts General Hospital at Newton Wellesley Hospital | Esophagogastric Cancer, Gastroesophageal Junction Adenocarcinoma | 1 |
| Massachusetts General Hospital at Newton-Wellesley Hospital | ER-Negative Breast Cancer, HER2-negative Breast Cancer, Invasive Breast Cancer | 1 |
| Neurocare Inc | Narcolepsy Type 1 | 1 |
| Neurocare, Inc. | OSA | 1 |
| Newton Wellesley Hospital Ambulatory Care Center | Lumbar Spinal Stenosis | 1 |
| Newton, Massachusetts | Idiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 2 | 1 |
| The Spiegel Center | Neck Muscle Issue | 1 |
Active & Upcoming Studies in Newton (2026)
Recruiting trials in Newton grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (13 active studies)
- ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer · Massachusetts General Hospital
- Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer · Phase 1, Phase 2 · Pfizer
Neurology & pain (4 active studies)
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). · Phase 3 · Eli Lilly and Company
- A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3) · Phase 3 · Bristol-Myers Squibb
Cardiovascular (1 active study)
Common conditions studied in Newton
- Alzheimer Disease (4 active studies)
- Gastroesophageal Junction Adenocarcinoma (3 active studies)
- Narcolepsy Type 1 (3 active studies)
- Alzheimers Disease (2 active studies)
- Breast Cancer (2 active studies)
- Esophageal Adenocarcinoma (2 active studies)
Leading research sponsors in Newton
- Massachusetts General Hospital
- Pfizer
- Bristol-Myers Squibb
- Alkermes, Inc.
- Hoffmann-La Roche
Frequently asked questions
How many paid clinical trials are currently recruiting in Newton?
There are approximately 33 recruiting clinical trials in Newton, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Newton pay participants?
Most recruiting trials in Newton compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Newton?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Newton?
The most common conditions under active study in Newton include Alzheimer Disease (4), Gastroesophageal Junction Adenocarcinoma (3), Narcolepsy Type 1 (3), Alzheimers Disease (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Newton?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Newton on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Newton?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Newton?
Recruiting research sites in Newton include Boston Center for Memory, Dana-Farber Cancer Institute - Chestnut Hill, Alkermes Investigational Site, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Newton right now?
The largest active categories in Newton are Cancer & tumors (13), Neurology & pain (4), Cardiovascular (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.