Assessing the Mechanisms and Impact of a Novel Cannabinoid Product for Gynecologic Pain
for Endometriosis
1 location in Belmont
Sponsor: Staci Gruber, Ph.D.
Sex: Female·Age: 21+
Code: NCT07728695·Phase 1, Phase 2·Recruiting·Listed Jul 27, 2026
Paid Clinical Trials in Belmont, MA
As of August 2026, 46 paid clinical trials are recruiting in Belmont, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Belmont offers studies at sites including McLean Hospital for conditions such as Schizophrenia, Psychosis, Schizoaffective Disorder, Bipolar Disorder. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Belmont
Trials by drug in Belmont
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Newly added in Belmont
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
35 clinical trials
A Study of Brenipatide in Adult Participants With Schizophrenia
for Schizophrenia
Drug: Brenipatide
Sites in Belmont, Watertown +30 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 55
Code: NCT07410507·Phase 2·Recruiting·Listed Feb 2026
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
for Alzheimer Disease
Drug: KarXT
Sites in Belmont, Boston +47 more locations
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Sex: All·Age: 55 - 90
Code: NCT06585787·Phase 3·Recruiting·Listed Sep 2024
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
for Psychosis Associated With Alzheimer's Disease
Drug: KarXT
Sites in Belmont, Boston +84 more locations
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Sex: All·Age: 55 - 90
Code: NCT05980949·Phase 3·Recruiting·Listed Aug 2023
Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)
for Schizophrenia
Drug: KarXT
Sites in Belmont, Boston +15 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT07101094·Recruiting·Listed Aug 2025
Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression
for Major Depression
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18+
Code: NCT07560878·EARLY_Phase 1·Recruiting·Listed May 2026
A Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder
for Borderline Personality Disorder (BPD)
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18+
Code: NCT07460947·Phase 1, Phase 2·Recruiting·Listed Mar 2026
Identifying Substance Use Consequences
for Substance Use Disorder (SUD)
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18+
Code: NCT07503067·Recruiting·Listed Mar 2026
Biomarkers to Enhance Early Schizophrenia Treatment
for Schizophenia Disorder
Sites in Belmont +3 more locations
Sponsor: Northwell Health
Sex: All·Age: 18 - 35
Code: NCT06969755·Phase 4·Recruiting·Listed May 2025
Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis
for Endometriosis
1 location in Belmont
Sponsor: Mclean Hospital
Sex: Female·Age: 21+
Code: NCT06477406·Phase 2·Recruiting·Listed Jun 2024
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
for Bipolar I Disorder
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 50
Code: NCT05837104·Phase 2·Recruiting·Listed May 2023
Mechanisms of Exposure Therapy for OCD
for Obsessive-Compulsive Disorder
Sites in Belmont +1 more location
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 65
Code: NCT06173752·Recruiting·Listed Dec 2023
Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents
for Rumination
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 13 - 18·Accepts healthy volunteers
Code: NCT04697966·Recruiting·Listed Jan 2021
Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder
for Bipolar I Disorder
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 45
Code: NCT06221852·Recruiting·Listed Jan 2024
Neural Correlates of Stress and Perceived Control in Adolescent Depression
for Major Depressive Disorder
1 location in Belmont
Sponsor: Mclean Hospital
Sex: Female·Age: 14 - 18·Accepts healthy volunteers
Code: NCT04788524·Recruiting·Listed Mar 2021
Interpretation Bias as a Mechanism of Treatment Response in OCD
for Obsessive-Compulsive Disorder
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18+
Code: NCT05224414·Recruiting·Listed Feb 2022
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation
for Depressive Disorder, Major
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 45·Accepts healthy volunteers
Code: NCT05232032·Phase 2·Recruiting·Listed Feb 2022
Pharmacologic Augmentation of TMS for Depression With D-serine
for Depression
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 80
Code: NCT06876129·Phase 1·Recruiting·Listed Mar 2025
Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder
for Bipolar Disorder
Sites in Belmont & Charlestown
Sponsor: Stony Brook University
Sex: All·Age: 18 - 45·Accepts healthy volunteers
Code: NCT06373016·Recruiting·Listed Apr 2024
Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services
for Schizophrenia Spectrum and Other Psychotic Disorders
Sites in Belmont, Boston +4 more locations
Sponsor: Beth Israel Deaconess Medical Center
Sex: All·Age: 18 - 40
Code: NCT06740383·Recruiting·Listed Dec 2024
PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product
for Chronic Pain
1 location in Belmont
Sponsor: Staci Gruber, Ph.D.
Sex: All·Age: 21+
Code: NCT03984565·Phase 2·Recruiting·Listed Jun 2019
Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder
for Bipolar Disorder
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 65
Code: NCT05457465·Phase 2·Recruiting·Listed Jul 2022
Enhanced Coordinated Specialty Care for Early Psychosis
for Psychosis
Sites in Belmont, Cambridge +3 more locations
Sponsor: Mclean Hospital
Sex: All·Age: All ages
Code: NCT06071858·Recruiting·Listed Oct 2023
Cerebellar Modulation of Cognition in Psychosis
for Schizophrenia
Sites in Belmont & Boston
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 55
Code: NCT06107764·Recruiting·Listed Oct 2023
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
for Schizophrenia
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 55
Code: NCT05343598·Recruiting·Listed Apr 2022
Cerebellar TMS and Satiety in Prader-Willi Syndrome
for Prader-Willi Syndrome
1 location in Belmont
Sponsor: Brigham and Women's Hospital
Sex: All·Age: 18 - 64
Code: NCT05938543·Recruiting·Listed Jul 2023
Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
for Appetitive Behavior
Sites in Belmont & Boston
Sponsor: Brigham and Women's Hospital
Sex: All·Age: 18 - 65·Accepts healthy volunteers
Code: NCT06105164·Recruiting·Listed Oct 2023
Stress Dynamics and Familial Risk for Depression in Female Adolescents
for Major Depressive Disorder
1 location in Belmont
Sponsor: Mclean Hospital
Sex: Female·Age: 13 - 15·Accepts healthy volunteers
Code: NCT06816329·Recruiting·Listed Feb 2025
Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression
for Major Depressive Disorder
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 45·Accepts healthy volunteers
Code: NCT05630963·Recruiting·Listed Nov 2022
Role of Parent Interpretation Bias in the Transmission of Anxiety to Children
for Anxiety
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 7+
Code: NCT05665491·Recruiting·Listed Dec 2022
MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction
for Schizophrenia and Related Disorders
Sites in Belmont +1 more location
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 35
Code: NCT06191965·Phase 2, Phase 3·Recruiting·Listed Jan 2024
Early Life Stress and Depression: Molecular and Functional Imaging
for Depression
1 location in Belmont
Sponsor: Mclean Hospital
Sex: Female·Age: 20 - 32·Accepts healthy volunteers
Code: NCT04713722·Recruiting·Listed Jan 2021
Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
for Alzheimer Disease
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 89
Code: NCT05245903·Recruiting·Listed Feb 2022
Individually Targeted Neuromodulation for Contamination-based OCD
for Obsessive-Compulsive Disorder
1 location in Belmont
Sponsor: Mclean Hospital
Sex: All·Age: 18 - 55
Code: NCT05048251·Recruiting·Listed Sep 2021
Study of ALTO-101 in Patients With Schizophrenia
for Schizophrenia
Sites in Belmont +12 more locations
Sponsor: Alto Neuroscience
Sex: All·Age: 21 - 55
Code: NCT06502964·Phase 2·Recruiting·Listed Jul 2024
Top Research Study Locations in Belmont
Researchers run research studies in Belmont, MA at 8 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| McLean Hospital | Psychosis, Schizoaffective Disorder, Schizophrenia | 38 |
| Harvard Mclean Hospital | Treatment Resistant Depression, Treatment Resistant Depression (TRD) | 1 |
| Local Institution - 0008 | Schizophrenia | 1 |
| Local Institution - 1223 | Psychosis Associated With Alzheimer's Disease | 1 |
| McLean | Schizophenia Disorder | 1 |
| McLean Hospital OnTrack Clinic | Bipolar Disorder, Psychosis, Psychosis Nos/Other | 1 |
| McLean OCDI | Obsessive-Compulsive Disorder | 1 |
| Oaks Building | Posttraumatic Stress Disorder (PTSD) | 1 |
Active & Upcoming Studies in Belmont (2026)
Recruiting trials in Belmont grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Mental health & behavior (27 active studies)
- MDMA-AT for PTSD in Young Adults With Childhood Trauma · Phase 2 · Jenna M. Traynor
- A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial · Phase 2, Phase 3 · NeuroRx, Inc.
Neurology & pain (3 active studies)
- A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4) · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product · Phase 2 · Staci Gruber, Ph.D.
Diabetes & metabolic (1 active study)
- Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans · Brigham and Women's Hospital
Common conditions studied in Belmont
- Schizophrenia (7 active studies)
- Psychosis (5 active studies)
- Schizoaffective Disorder (5 active studies)
- Bipolar Disorder (3 active studies)
- Bipolar I Disorder (3 active studies)
- Cognitive Impairment (3 active studies)
Leading research sponsors in Belmont
- Mclean Hospital
- Brigham and Women's Hospital
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Staci Gruber, Ph.D.
- Alto Neuroscience
Frequently asked questions
How many paid clinical trials are currently recruiting in Belmont?
There are approximately 46 recruiting clinical trials in Belmont, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Belmont pay participants?
Most recruiting trials in Belmont compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Belmont?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Belmont?
The most common conditions under active study in Belmont include Schizophrenia (7), Psychosis (5), Schizoaffective Disorder (5), Bipolar Disorder (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Belmont?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Belmont on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Belmont?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Belmont?
Recruiting research sites in Belmont include McLean Hospital, Harvard Mclean Hospital, Local Institution - 0008, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Belmont right now?
The largest active categories in Belmont are Mental health & behavior (27), Neurology & pain (3), Diabetes & metabolic (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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