Paid Clinical Trials in Methuen, MA
As of August 2026, 24 paid clinical trials are recruiting in Methuen, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Methuen offers studies at sites including Dana Farber-Merrimack Valley for conditions such as Breast Cancer, Chronic Weight Management, Obesity, Overweight. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Methuen
Trials by drug in Methuen
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Newly added in Methuen
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
24 clinical trials
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
ATEMPT 2.0: Adjuvant T-DM1 vs TH
EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations
Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome
SURGE: Supporting UnderRepresented Minorities in Genomics-based Cancer Trial Enrollment (Intervention)
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Top Research Study Locations in Methuen
Researchers run research studies in Methuen, MA at 14 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Dana Farber-Merrimack Valley | Stage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma | 8 |
| ActivMed Practices and Research | Alzheimer's Disease, Hypothyroidism | 2 |
| Activmed Practices & Research, Llc - Methuen | Depression, Major Depressive Disorder, Major Depressive Disorder (MDD) | 2 |
| Dana-Farber Cancer Instiute - Merrimack Valley | Breast Cancer, Gastrointestinal Cancer, HER2-positive Breast Cancer | 2 |
| ACCOMPLISH-1 Research Site | Chronic Weight Management, Obesity, Overweight | 1 |
| ACCOMPLISH-2 Research Site | Chronic Weight Management, Obesity, Overweight | 1 |
| ActivMed Practices & Research | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hypertension | 1 |
| Clinical Study Site | Non-Small Cell Lung Cancer | 1 |
| Dana Farber Cancer Institute - Merrimack Valley | Breast Cancer | 1 |
| Dana Farber Cancer Institute at Merrimack Valley | B-cell Malignancy, Low-grade, Hematological Malignancies, IgG Monoclonal Gammopathy of Uncertain Significance | 1 |
| Dana-Farber Cancer Institude at Merrimack Valley | Triple Negative Breast Cancer | 1 |
| Dana-Farber Cancer Institute - Merrimack Valley | Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer | 1 |
| Dana-Farber Cancer Institute Merrimack Valley | Metastatic Breast Cancer | 1 |
| Dana-Farber Cancer Instiute Merrimack Valley | EGFR Gene Mutation, Lung Cancer | 1 |
Active & Upcoming Studies in Methuen (2026)
Recruiting trials in Methuen grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (17 active studies)
- EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations · Dana-Farber Cancer Institute
- Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer · Phase 3 · Alliance for Clinical Trials in Oncology
Diabetes & metabolic (3 active studies)
- A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Mental health & behavior (1 active study)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
Cardiovascular (1 active study)
Common conditions studied in Methuen
- Breast Cancer (3 active studies)
- Chronic Weight Management (2 active studies)
- Obesity (2 active studies)
- Overweight (2 active studies)
- Stage IIIB Lung Cancer AJCC v8 (2 active studies)
- Advanced Esophageal Adenocarcinoma (1 active study)
Leading research sponsors in Methuen
- Alliance for Clinical Trials in Oncology
- Dana-Farber Cancer Institute
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- NRG Oncology
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Methuen?
There are approximately 24 recruiting clinical trials in Methuen, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Methuen pay participants?
Most recruiting trials in Methuen compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Methuen?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Methuen?
The most common conditions under active study in Methuen include Breast Cancer (3), Chronic Weight Management (2), Obesity (2), Overweight (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Methuen?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Methuen on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Methuen?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Methuen?
Recruiting research sites in Methuen include Dana Farber-Merrimack Valley, ActivMed Practices and Research, Activmed Practices & Research, Llc - Methuen, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Methuen right now?
The largest active categories in Methuen are Cancer & tumors (17), Diabetes & metabolic (3), Mental health & behavior (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.