Paid Clinical Trials in Cambridge, MA
As of August 2026, 48 paid clinical trials are recruiting in Cambridge, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Cambridge offers studies at sites including Massachusetts Institute of Technology for conditions such as Spinal Cord Injuries, Alzheimer Disease, Amputation, Chronic Pain. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Cambridge
Trials by drug in Cambridge
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Newly added in Cambridge
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Digital Coach to Support Exposure Therapy Homework for Anxious Youth
40 clinical trials
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury
A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone
The Mycophenolate Pregnancy Registry
Evaluating the Acceptability, Feasibility and Usability of Various Conversational Data Collection Software
A Survey to Assess Participants' and Physicians' Knowledge When Using GATTEX (Knowledge Assessment Survey)
Home Use Study of Targeted Mechanical Stimulation for Tremor Relief
Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis
Evaluation of a Powered Ankle Prosthesis Capable of Bidirectional Control Via Neural Recording and Cutaneous Stimulation in Free-Space and Walking Tasks
Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
Promoting Recovery After Brain Injury Using Focused Ultrasound
Investigating the Effects of Cannabidiol on Social Anxiety Disorder
A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception
AMI Construction in Lower Extremity Residual Limbs
Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease
BE WELL With Migraine: Brain Education and WELLness With Migraine
Improving Mental Health Treatment for Individuals in Crisis Interacting With the Criminal-Legal System
Modulating Exercise Dosage to Improve Concussion Recovery
TCF-001 TRACK (Target Rare Cancer Knowledge) Study
Low Oxygen Therapy to Enhance Walking Recovery After SCI.
Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury
Combination Therapy to Improve SCI Recovery.
Gamma Frequency Stimulation in Individuals With Down Syndrome
High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease
Yoga Breath Training to Improve Cardiorespiratory Synchrony in Spinal Cord Injury
Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy
Optimization of NIBS for Treatment of Addiction
Enhanced Coordinated Specialty Care for Early Psychosis
Evaluation of a Neural-Controlled Powered Prosthesis Across Diverse Real-World Tasks
Mechanisms of Open and Hidden Placebo in Stroke Recovery
Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial
Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response
Family Connections
Researching Heat and Yoga for Mood Enhancement
Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise
Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy
Pre-exposure Prophylaxis (PrEP) for Health
Extracorporeal Shockwave Therapy (ESWT) for the Management of Stress Fractures and High-grade Bone Stress Injuries (BSIs)
Top Research Study Locations in Cambridge
Researchers run research studies in Cambridge, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Massachusetts Institute of Technology | Alzheimer Disease, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset | 7 |
| Spaulding Rehabilitation Hospital | Spinal Cord Injuries, Aerobic Exercise, Concussion, Brain | 7 |
| MIT Media Lab | Amputation, Knee Osteoarthristis, Transfemoral Amputation | 3 |
| Spaulding Hospital Cambridge | Fibromyalgia, Pain, Hemiparesis, Phantom Limb Pain | 3 |
| Cambridge Health Alliance | Behavior Disorders in Children, Emotional Disturbance, Psychiatric Disorders | 2 |
| Spaulding Cambridge Hospital | ACL Injuries, Achilles Injuries Tendon, Achilles Tendinitis, Left Leg | 2 |
| AIDS Action | HIV (Human Immunodeficiency Virus), Substance Dependence | 1 |
| AugMend Health at MIT.nano Immersion Lab | Behavioral Health Challenges, Chronic Pain, Ecological Momentary Assessment Best Practices | 1 |
| Biogen | Postpartum Depression | 1 |
| Breathe Yoga Studio | Depression | 1 |
| Cambridge Health Alliance - Center for Mindfulness and Compassion | Migraine | 1 |
| Cambridge Health Alliance RISE Clinic | Bipolar Disorder, Psychosis, Psychosis Nos/Other | 1 |
| Encora Therapeutics | Essential Tremor, Parkinson's Disease | 1 |
| Harvard - Spaulding Rehabilitation Hospital | Bone Stress Fracture, Bones Stress Injury | 1 |
| Harvard Medical Center | Pain, Tibial Fractures | 1 |
| Harvard University | Anxiety Disorders, OCD | 1 |
| MIT | Alzheimer Disease, Cognitively Healthy People | 1 |
| MIT Media Laboratory | Transtibial Amputation - Unilateral | 1 |
| Massachusetts Institute of Technology (MIT) | Schizophrenia Spectrum Disorders | 1 |
| Massachusetts Institute of Technology - McGovern Institute for Brain Research | Healthy Volunteers, no Condition, Basic Science | 1 |
| Massachusetts Institute of Technology Media Lab | Amputation | 1 |
| New England Ambulatory SurgiCenter | Lumbar Spinal Stenosis | 1 |
| Orange Door Collaborative | Depression | 1 |
| Quintiles Outcome | Heart Transplantation, Kidney Transplantation, Liver Transplantation, Autoimmune Diseases | 1 |
| Spaulding Rehabilitation | Blood Pressure Disorders, Spinal Cord Injuries | 1 |
Active & Upcoming Studies in Cambridge (2026)
Recruiting trials in Cambridge grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Neurology & pain (13 active studies)
- Extracorporeal Shockwave Therapy and Platelet-Rich Plasma for Midportion Achilles Tendinopathy · Spaulding Rehabilitation Hospital
- Effects of taVNS on Fibromyalgia Pain · Spaulding Rehabilitation Hospital
Mental health & behavior (7 active studies)
- Digital Coach to Support Exposure Therapy Homework for Anxious Youth · Massachusetts General Hospital
- Gamma Light and Sound Stimulation in Schizophrenia · Massachusetts Institute of Technology
HIV / STI (1 active study)
- Pre-exposure Prophylaxis (PrEP) for Health · Brown University
Cancer & tumors (1 active study)
- TCF-001 TRACK (Target Rare Cancer Knowledge) Study · TargetCancer Foundation
Cardiovascular (1 active study)
- The Mycophenolate Pregnancy Registry · Genentech, Inc.
Pediatric (1 active study)
- Family Connections · Cambridge Health Alliance
Common conditions studied in Cambridge
- Spinal Cord Injuries (6 active studies)
- Alzheimer Disease (3 active studies)
- Amputation (3 active studies)
- Chronic Pain (2 active studies)
- Knee Osteoarthristis (2 active studies)
- ACL Injuries (1 active study)
Leading research sponsors in Cambridge
- Massachusetts Institute of Technology
- Spaulding Rehabilitation Hospital
- Massachusetts General Hospital
- Brigham and Women's Hospital
- Cambridge Health Alliance
Frequently asked questions
How many paid clinical trials are currently recruiting in Cambridge?
There are approximately 48 recruiting clinical trials in Cambridge, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Cambridge pay participants?
Most recruiting trials in Cambridge compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Cambridge?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Cambridge?
The most common conditions under active study in Cambridge include Spinal Cord Injuries (6), Alzheimer Disease (3), Amputation (3), Chronic Pain (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Cambridge?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cambridge on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Cambridge?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Cambridge?
Recruiting research sites in Cambridge include Massachusetts Institute of Technology, Spaulding Rehabilitation Hospital, MIT Media Lab, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Cambridge right now?
The largest active categories in Cambridge are Neurology & pain (13), Mental health & behavior (7), HIV / STI (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.