As of July 2026, 97 paid clinical trials are recruiting in Springfield, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Springfield offers studies at sites including Baystate Medical Center for conditions such as Stroke, Alzheimer Disease, Atrial Fibrillation, Coronary Artery Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Springfield has approximately 97 recruiting research studies across a wide range of therapeutic areas. Massachusetts is a global epicenter of biomedical research, anchored by Harvard-affiliated hospitals (MGH, Brigham and Women's, Dana-Farber), Boston Children's Hospital, and the Kendall Square biotech corridor in Cambridge.
Researchers run research studies in Springfield, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Baystate Medical Center | Stroke, Anatomic Stage II Breast Cancer AJCC v8, Atrial Fibrillation | 43 |
| Mercy Medical Center | Advanced Lung Non-Small Cell Carcinoma, Anatomic Stage IV Breast Cancer AJCC v8, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative | 10 |
| Baystate Health | Coronary Artery Disease, Heart Diseases, Atrial Fibrillation | 5 |
| Elixia MA | Alzheimer Disease, Bipolar Disorder, Treatment Resistant Depression | 3 |
| Elixia Health - Springfield - Elixia - PPDS | Alzheimer Disease, Type II Diabetes Mellitus | 2 |
| Elixia MA, LLC | Agitation, Major Depressive Disorder | 2 |
| New England Retina Consultants | DME, Diabetic Macular Edema, Diabetic Macular Edema (DME) | 2 |
| Elixia - Springfield | Generalized Anxiety Disorder (GAD), Bipolar I or II Disorder | 2 |
| Bay State Medical Center | Rheumatic Joint Disease | 1 |
| Baystate Children's Hospital | Bronchiolitis Acute | 1 |
| Baystate Clinical Trials Unit | OSA | 1 |
| Baystate Medical Center Inc. | Triple Negative Breast Cancer | 1 |
| Baystate Pain Management Center | Lumbar Spinal Stenosis | 1 |
| Behavioral Health Network | Mental Health Disorder, Opioid Use Disorder | 1 |
| Caring Health Center | Breast Cancer Screening, Cervical Cancer Screening, Colon Cancer Screening | 1 |
| Caring Health Center, Inc. | Hypertension, Medication Adherence | 1 |
| Direct Biologics Investigational Site | ARDS, Acute Respiratory Distress Syndrome | 1 |
| ELIXIA | Major Depressive Disorder | 1 |
| Elixia Health | Major Depressive Disorder | 1 |
| Elixia SISU BHR - Sprinfield | Chronic Idiopathic Constipation (CIC) | 1 |
| Elixia SISU BHR - Springfield | Cortisol Excess, Type 2 Diabetes | 1 |
| Holyoke Medical Center | Chronic Kidney Diseases, Type 2 Diabetes Mellitus | 1 |
| Kidney Care and Transplant Services of NE | Arteriovenous Fistula, End-stage Renal Disease, Kidney Disease, End-Stage | 1 |
| Local Institution - 0042 | Colitis, Ulcerative | 1 |
| Local Institution - 1239 | Psychosis Associated With Alzheimer's Disease | 1 |
Recruiting trials in Springfield grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Massachusetts are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Massachusetts trials follow additional state privacy requirements enforced under 201 CMR 17.00 and oversight from the Massachusetts Department of Public Health.
Hipa.ai aggregates every recruiting study in Springfield from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 97 recruiting clinical trials in Springfield, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Springfield compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Springfield include Stroke (4), Alzheimer Disease (3), Atrial Fibrillation (3), Coronary Artery Disease (3), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Springfield on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Springfield include Baystate Medical Center, Mercy Medical Center, Baystate Health, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Springfield are Cancer & tumors (33), Cardiovascular (9), Mental health & behavior (8). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.