Non-invasive Prediction of EArly Cardiac rEjection
for Heart Transplant
Sites in Boston +21 more locations
Sponsor: Vanderbilt University Medical Center
Sex: All·Age: 6 - 25
Code: NCT07770659·Recruiting·Listed Aug 18, 2026
Clinical Trials at Boston Children's Hospital
As of September 2026, 216 paid clinical trials are recruiting at Boston Children's Hospital, located at 11 HEREFORD ST, APT 4R, BOSTON, MA 02115-1602, phone (617) 602-9730 in Boston, Massachusetts. Active studies at this site cover conditions such as Breast Cancer, Prostate Cancer and Ovarian Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
View the full facility profile →
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Boston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
217 clinical trials at Boston Children's Hospital
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A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
for Sickle Cell Disease
Drug: Etavopivat
Sites in Boston +43 more locations
Sponsor: Novo Nordisk A/S
Sex: All·Age: 12+
Code: NCT06612268·Phase 3·Recruiting·Listed Sep 2024
Pompe Disease Registry Protocol
for Glycogen Storage Disease Type II
Sites in Boston, Springfield +72 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00231400·Recruiting·Listed Oct 2005
Fabry Disease Registry & Pregnancy Sub-registry
for Fabry Disease
Sites in Boston, Springfield +72 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00196742·Recruiting·Listed Sep 2005
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
for Colitis, Ulcerative
Sites in Boston, Worcester +16 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 2 - 17
Code: NCT05076175·Phase 2, Phase 3·Recruiting·Listed Oct 2021
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
for Complex Congenital Heart Defect
Sites in Boston +20 more locations
Sponsor: Edwards Lifesciences
Sex: All·Age: All ages
Code: NCT02744677·Recruiting·Listed Apr 2016
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
for Attention-Deficit/Hyperactivity Disorder
Sites in Boston +46 more locations
Sponsor: Supernus Pharmaceuticals, Inc.
Sex: All·Age: 48 Months - 69 Months
Code: NCT04781140·Phase 4·Recruiting·Listed Mar 2021
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
for Single Ventricle Heart Disease
Sites in Boston +36 more locations
Sponsor: Mezzion Pharma Co. Ltd
Sex: All·Age: 12 - 18
Code: NCT05918211·Phase 3·Recruiting·Listed Jun 2023
Child and Adolescent Registry for Participants With Narcolepsy
for Narcolepsy
Sites in Boston +24 more locations
Sponsor: Jazz Pharmaceuticals
Sex: All·Age: Up to 17
Code: NCT04899947·Recruiting·Listed May 2021
A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively
for Schizophrenia
Drug: KarXT
Sites in Boston, Lexington +47 more locations
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Sex: All·Age: 5 - 17
Code: NCT07424404·Phase 3·Recruiting·Listed Feb 2026
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
for Schizophrenia
Drug: KarXT
Sites in Boston, Worcester +19 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 13 - 17
Code: NCT07288567·Phase 3·Recruiting·Listed Dec 2025
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
for Spinal Muscular Atrophy (SMA)
Sites in Boston +14 more locations
Sponsor: argenx
Sex: All·Age: 5 - 17
Code: NCT07287982·Phase 2·Recruiting·Listed Dec 2025
Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)
for Fragile X Syndrome
Sites in Boston, Worcester +13 more locations
Sponsor: Mirum Pharmaceuticals, Inc.
Sex: Male·Age: 13 - 45
Code: NCT07209462·Phase 2·Recruiting·Listed Oct 2025
Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
for GRIN-related Neurodevelopmental Disorder
Sites in Boston +16 more locations
Sponsor: GRIN Therapeutics, Inc.
Sex: All·Age: 1 Month - 18
Code: NCT07224581·Phase 3·Recruiting·Listed Nov 2025
A Long-term Follow-up Study in Patients Who Received BEAM-101
for Hemoglobinopathy
Sites in Boston +16 more locations
Sponsor: Beam Therapeutics Inc.
Sex: All·Age: 14 - 37
Code: NCT07373639·Recruiting·Listed Jan 2026
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
for Obesity
Sites in Boston +50 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 6 - 17
Code: NCT06672549·Phase 3·Recruiting·Listed Nov 2024
A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)
for PIK3CA-Related Overgrowth Spectrum (PROS)
Sites in Boston +21 more locations
Sponsor: Relay Therapeutics, Inc.
Sex: All·Age: 2+
Code: NCT06789913·Phase 2·Recruiting·Listed Jan 2025
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
for Spinal Muscular Atrophy
Sites in Boston +14 more locations
Sponsor: Alcyone Therapeutics, Inc
Sex: All·Age: 3+
Code: NCT05866419·Recruiting·Listed May 2023
REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome
for Angelman Syndrome
Sites in Boston +17 more locations
Sponsor: Ionis Pharmaceuticals, Inc.
Sex: All·Age: 2 - 50
Code: NCT06914609·Phase 3·Recruiting·Listed Apr 2025
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
for Heart Failure
Sites in Boston +19 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 29 Days - 17
Code: NCT05714085·Phase 2, Phase 3·Recruiting·Listed Feb 2023
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
for Systemic Lupus Erythematosus
Sites in Boston, Worcester +16 more locations
Sponsor: Cabaletta Bio
Sex: All·Age: 18 - 65
Code: NCT06121297·Phase 1, Phase 2·Recruiting·Listed Nov 2023
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
for Muscular Atrophy, Spinal
Sites in Boston +9 more locations
Sponsor: Biogen
Sex: All·Age: 3+
Code: NCT06555419·Phase 1·Recruiting·Listed Aug 2024
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
for Crohn's Disease
Sites in Boston +14 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 2 - 17
Code: NCT05509777·Phase 3·Recruiting·Listed Aug 2022
Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age
for Hyperkalemia
Drug: patiromer
Sites in Boston +10 more locations
Sponsor: Vifor Pharma, Inc.
Sex: All·Age: 0 - 11
Code: NCT05766839·Phase 2·Recruiting·Listed Mar 2023
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
for Ulcerative Colitis
Sites in Boston, Waltham +9 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 2 - 19
Code: NCT04844606·Phase 3·Recruiting·Listed Apr 2021
4D-710 in Adult Patients With Cystic Fibrosis
for Cystic Fibrosis Lung
Sites in Boston +17 more locations
Sponsor: 4D Molecular Therapeutics
Sex: All·Age: 18+
Code: NCT05248230·Phase 2·Recruiting·Listed Feb 2022
Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease
for Crohn's Disease
Drug: Upadacitinib
Sites in Boston +11 more locations
Sponsor: AbbVie
Sex: All·Age: 2 - 17
Code: NCT06332534·Phase 3·Recruiting·Listed Mar 2024
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
for Dravet Syndrome
Sites in Boston +10 more locations
Sponsor: Encoded Therapeutics
Sex: All·Age: 6 Months - 17
Code: NCT05419492·Phase 1, Phase 2·Recruiting·Listed Jun 2022
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
for Ulcerative Colitis
Sites in Boston +19 more locations
Sponsor: Pfizer
Sex: All·Age: 12 - 17
Code: NCT05287126·Phase 2·Recruiting·Listed Mar 2022
Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis
for Cystic Fibrosis
Sites in Boston +11 more locations
Sponsor: Arcturus Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06747858·Phase 2·Recruiting·Listed Dec 2024
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
for Crohn's Disease (CD)
Sites in Boston +14 more locations
Sponsor: Takeda
Sex: All·Age: 2 - 17
Code: NCT04779320·Phase 3·Recruiting·Listed Mar 2021
A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)
for Phenylketonuria (PKU)
Drug: Palynziq
Sites in Boston +11 more locations
Sponsor: BioMarin Pharmaceutical
Sex: All·Age: All ages
Code: NCT05813678·Recruiting·Listed Apr 2023
A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)
for Phenylketonuria (PKU)
Drug: Palynziq
Sites in Boston +10 more locations
Sponsor: BioMarin Pharmaceutical
Sex: All·Age: All ages
Code: NCT06305234·Recruiting·Listed Mar 2024
52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism
for Hypogonadism, Male
Sites in Boston, Worcester +18 more locations
Sponsor: Halozyme Therapeutics
Sex: Male·Age: 12 - 17
Code: NCT06689085·Phase 3·Recruiting·Listed Nov 2024
Minima Stent System Post- Approval Study (PAS)
for Pulmonary Artery Stenosis
Sites in Boston +14 more locations
Sponsor: Renata Medical
Sex: All·Age: All ages
Code: NCT06828770·Recruiting·Listed Feb 2025
A Multicenter Multinational Observational Study of Children With Hypochondroplasia
for Hypochondroplasia
Sites in Boston +15 more locations
Sponsor: BioMarin Pharmaceutical
Sex: All·Age: Up to 15
Code: NCT06212947·Recruiting·Listed Jan 2024
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease (IFALD).
for Intestinal Failure Associated Liver Disease
Sites in Boston +12 more locations
Sponsor: NorthSea Therapeutics B.V.
Sex: All·Age: 16+
Code: NCT05919680·Phase 2·Recruiting·Listed Jun 2023
Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia
for RPS19 Deficient Diamond-Blackfan Anemia
Sites in Boston +1 more location
Sponsor: Apriligen, Inc.
Sex: All·Age: 2 - 25
Code: NCT07476183·Phase 1·Recruiting·Listed Mar 2026
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
for Catecholaminergic Polymorphic Ventricular Tachycardia
Sites in Boston +3 more locations
Sponsor: Solid Biosciences Inc.
Sex: All·Age: 7+
Code: NCT07148089·Phase 1·Recruiting·Listed Aug 2025
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study
for Congenital Heart Disease
Sites in Boston +8 more locations
Sponsor: Starlight Cardiovascular Inc
Sex: All·Age: 1 Minute - 6 Months
Code: NCT07114718·Recruiting·Listed Aug 2025
AERA Pediatrics Registry
for Dysfunction of Eustachian Tube
Sites in Boston +8 more locations
Sponsor: Integra LifeSciences Corporation
Sex: All·Age: Up to 18
Code: NCT07071298·Recruiting·Listed Jul 2025
Common conditions studied in Boston
- Breast Cancer (64 active studies)
- Prostate Cancer (41 active studies)
- Ovarian Cancer (36 active studies)
- Heart Failure (34 active studies)
- Acute Myeloid Leukemia (32 active studies)
- Colorectal Cancer (32 active studies)
Leading research sponsors in Boston
- Massachusetts General Hospital
- Brigham and Women's Hospital
- Dana-Farber Cancer Institute
- Boston Children's Hospital
- Beth Israel Deaconess Medical Center
Frequently asked questions
How many paid clinical trials are currently recruiting in Boston?
There are approximately 2,894 recruiting clinical trials in Boston, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Boston pay participants?
Most recruiting trials in Boston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Boston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Boston?
The most common conditions under active study in Boston include Breast Cancer (64), Prostate Cancer (41), Ovarian Cancer (36), Heart Failure (34), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Boston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Boston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Boston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Boston?
Recruiting research sites in Boston include Massachusetts General Hospital, Brigham and Women's Hospital, Dana-Farber Cancer Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Boston right now?
The largest active categories in Boston are Cancer & tumors (879), Neurology & pain (218), Cardiovascular (187). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Boston Children's Hospital?
Boston Children's Hospital is located at 11 HEREFORD ST, APT 4R, BOSTON, MA 02115-1602. Use the Google Maps link in the intro above to get directions.
How do I contact Boston Children's Hospital?
You can reach Boston Children's Hospital by phone at (617) 602-9730. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
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