Colorectal cancer Clinical Trials in Grand Rapids, MI
As of July 2026, 27 paid clinical trials are recruiting for Colorectal cancer in Grand Rapids, Michigan. Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Grand Rapids
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27 clinical trials for Colorectal cancer
·Clear filters·↓ Download CSVA Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
A Study of MGC028 in Participants With Advanced Solid Tumors
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer
A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers
A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors
177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors
A Study of MGC026 in Participants With Advanced Solid Tumors
Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE)
A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors
CT-95 in Advanced Cancers Associated With Mesothelin Expression
64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
About research studies in Grand Rapids
Grand Rapids has approximately 435 recruiting research studies across a wide range of therapeutic areas. Michigan hosts University of Michigan Health, Henry Ford Health, and Corewell Health, running trials across oncology, neurology, and cardiology with a strong focus on precision medicine.
Top Research Study Locations in Grand Rapids
Researchers run research studies in Grand Rapids, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 63 |
| Trinity Health Grand Rapids Hospital | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Advanced Lung Non-Small Cell Carcinoma | 60 |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 57 |
| START Midwest | Advanced Solid Tumor, Colorectal Cancer, Endometrial Cancer | 57 |
| Corewell Health | Amblyopia, Atrial Fibrillation, Large B-cell Lymphoma | 44 |
| Helen DeVos Children's Hospital | Cystic Fibrosis, Focal Segmental Glomerulosclerosis, ATRT Recurrent | 16 |
| BAMF Health | Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Prostate Cancer | 9 |
| Helen DeVos Children's Hospital at Spectrum Health | Muscular Atrophy, Spinal, Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 8 |
| START Midwest, LLC | Advanced Solid Tumors, Advanced Breast Cancer, Advanced NRAS-Mutant Melanoma | 8 |
| Spectrum Health at Butterworth Campus | Metastatic Malignant Neoplasm in the Brain, Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 8 |
| Cancer and Hematology Centers of Western Michigan | Diffuse Large B-cell Lymphoma (DLBCL), Limited-stage Small Cell Lung Cancer (LS-SCLC), Metastatic Breast Cancer | 8 |
| South Texas Accelerated Research Therapeutics (START) Midwest | Advanced Solid Tumors, Colorectal Cancer, Colorectal Carcinoma | 7 |
| Corewell Health West | Angina Pectoris, Atrial Fibrillation, Chest Pain | 5 |
| Foundation for Vision Research | DME, Diabetic Macular Edema, Diabetic Macular Edema (DME) | 5 |
| Spectrum Health | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases | 5 |
| The Cancer & Hematology Centers | Breast Cancer, Carcinoma, Non-Small-Cell Lung, Colonic Diseases | 4 |
| GSK Investigational Site | Breast Neoplasms, Multiple Myeloma, Neoplasms | 4 |
| START - Midwest | Advanced Solid Tumors, Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC), Advanced or Metastatic ER+ HER2- Breast Cancer (mBC) | 4 |
| Spectrum Health Medical Group | Bladder Cancer, Cardiovascular Diseases, Colorectal Disorders | 4 |
| The Cancer and Hematology Centers | B Cell Lymphoma, Chronic Lymphocytic Leukemia, Extra-Pancreatic Neuroendocrine Tumor (epNET) | 4 |
| Cancer & Hematology Centers of Western Michigan | Bladder Carcinoma, Breast Cancer, Cutaneous Melanoma | 4 |
| BAMF Health Inc. | Breast Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms | 3 |
| Infusion Associates - Grand Rapids | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 3 |
| Pediatric Ophthalmology, P.C. | Amblyopia | 3 |
| BAMF Health, Inc. | Cholesterol, Colorectal Cancer, Esophageal Cancer | 2 |
Active & Upcoming Studies in Grand Rapids (2026)
Recruiting trials in Grand Rapids grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (231 active studies)
- Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE) · Phase 2, Phase 3 · GE Healthcare
- A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer · Phase 1 · Aktis Oncology, Inc.
Cardiovascular (23 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Clinical Evaluation of Radiation Reduction for Optimized Safety · Angiowave Imaging
Neurology & pain (14 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- Clinical Evaluation of Radiation Reduction for Optimized Safety · Angiowave Imaging
Eye & vision (7 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
Mental health & behavior (6 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Diabetes & metabolic (4 active studies)
Pediatric (3 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine · Phase 3 · H. Lundbeck A/S
Common conditions studied in Grand Rapids
- Colorectal Cancer (16 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Advanced Solid Tumors (14 active studies). Recruiting Advanced Solid Tumors studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumor (13 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (11 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Ovarian Cancer (10 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Endometrial Cancer (9 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Grand Rapids
- National Cancer Institute (NCI)
- Children's Oncology Group
- SWOG Cancer Research Network
- AstraZeneca
- Merck Sharp & Dohme LLC
Local regulations and guidelines
Clinical trials in Michigan are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Michigan research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Grand Rapids. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Grand Rapids
Hipa.ai aggregates every recruiting study in Grand Rapids from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Grand Rapids?
There are approximately 435 recruiting clinical trials in Grand Rapids, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Grand Rapids pay participants?
Most recruiting trials in Grand Rapids compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Grand Rapids?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Grand Rapids?
The most common conditions under active study in Grand Rapids include Colorectal Cancer (16), Advanced Solid Tumors (14), Advanced Solid Tumor (13), Breast Cancer (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Grand Rapids?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Grand Rapids on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Grand Rapids?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Grand Rapids?
Recruiting research sites in Grand Rapids include Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Trinity Health Grand Rapids Hospital, Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Grand Rapids right now?
The largest active categories in Grand Rapids are Cancer & tumors (231), Cardiovascular (23), Neurology & pain (14). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.