Oncology Clinical Trials in Grand Rapids, MI
As of July 2026, 172 paid clinical trials are recruiting for Oncology in Grand Rapids, Michigan. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Grand Rapids
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
175 clinical trials for Oncology
·Clear filters·↓ Download CSVA Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
A Phase 1/1b Study of IAM1363 in HER2 Cancers
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors
Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
A Study of PHST001 in Advanced Solid Tumors
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
About research studies in Grand Rapids
Grand Rapids has approximately 413 recruiting research studies across a wide range of therapeutic areas. Michigan hosts University of Michigan Health, Henry Ford Health, and Corewell Health, running trials across oncology, neurology, and cardiology with a strong focus on precision medicine.
Top Research Study Locations in Grand Rapids
Researchers run research studies in Grand Rapids, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 59 |
| Trinity Health Grand Rapids Hospital | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Advanced Lung Non-Small Cell Carcinoma | 54 |
| START Midwest | Colorectal Cancer, Advanced Solid Tumor, Endometrial Cancer | 54 |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 52 |
| Corewell Health | Amblyopia, Large B-cell Lymphoma, Non-Hodgkin Lymphoma | 41 |
| Helen DeVos Children's Hospital | Cystic Fibrosis, Focal Segmental Glomerulosclerosis, ATRT Recurrent | 16 |
| BAMF Health | Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Prostate Cancer | 9 |
| Helen DeVos Children's Hospital at Spectrum Health | Muscular Atrophy, Spinal, Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 8 |
| START Midwest, LLC | Advanced Solid Tumors, Advanced Breast Cancer, Advanced NRAS-Mutant Melanoma | 8 |
| Spectrum Health at Butterworth Campus | Metastatic Malignant Neoplasm in the Brain, Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 8 |
| Cancer and Hematology Centers of Western Michigan | Diffuse Large B-cell Lymphoma (DLBCL), Limited-stage Small Cell Lung Cancer (LS-SCLC), Metastatic Breast Cancer | 8 |
| South Texas Accelerated Research Therapeutics (START) Midwest | Advanced Solid Tumors, Colorectal Cancer, Colorectal Carcinoma | 7 |
| Corewell Health West | Angina Pectoris, Atrial Fibrillation, Chest Pain | 5 |
| START - Midwest | Advanced Solid Tumors, Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC), Advanced or Metastatic ER+ HER2- Breast Cancer (mBC) | 5 |
| Spectrum Health | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases | 5 |
| The Cancer & Hematology Centers | Breast Cancer, Carcinoma, Non-Small-Cell Lung, Colonic Diseases | 4 |
| Foundation for Vision Research | DME, Diabetic Macular Edema, Diabetic Macular Edema (DME) | 4 |
| GSK Investigational Site | Breast Neoplasms, Multiple Myeloma, Neoplasms | 4 |
| Spectrum Health Medical Group | Bladder Cancer, Cardiovascular Diseases, Colorectal Disorders | 4 |
| The Cancer and Hematology Centers | B Cell Lymphoma, Chronic Lymphocytic Leukemia, Extra-Pancreatic Neuroendocrine Tumor (epNET) | 4 |
| Cancer & Hematology Centers of Western Michigan | Bladder Carcinoma, Breast Cancer, Cutaneous Melanoma | 4 |
| BAMF Health Inc. | Breast Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms | 3 |
| Pediatric Ophthalmology, P.C. | Amblyopia | 3 |
| Cancer And Hematology Centers of Western Michigan PC | Colorectal Neoplasms, Multiple Myeloma | 2 |
| Corewell Health (Spectrum) | Aortic Aneurysm, Abdominal, Aortic Stenosis | 2 |
Active & Upcoming Studies in Grand Rapids (2026)
Recruiting trials in Grand Rapids grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (222 active studies)
- Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE) · Phase 2, Phase 3 · GE Healthcare
- A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer · Phase 1 · Aktis Oncology, Inc.
Cardiovascular (20 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Clinical Evaluation of Radiation Reduction for Optimized Safety · Angiowave Imaging
Neurology & pain (11 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- Clinical Evaluation of Radiation Reduction for Optimized Safety · Angiowave Imaging
Eye & vision (6 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
Mental health & behavior (5 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Diabetes & metabolic (4 active studies)
Pediatric (2 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- Randomized Study in Children and Adolescents With Migraine: Acute Treatment · Phase 3 · Pfizer
Common conditions studied in Grand Rapids
- Colorectal Cancer (15 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Advanced Solid Tumors (13 active studies). Recruiting Advanced Solid Tumors studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumor (11 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (10 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Ovarian Cancer (10 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Endometrial Cancer (9 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Grand Rapids
- National Cancer Institute (NCI)
- Children's Oncology Group
- SWOG Cancer Research Network
- AstraZeneca
- Merck Sharp & Dohme LLC
Local regulations and guidelines
Clinical trials in Michigan are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Michigan research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Grand Rapids. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Grand Rapids
Hipa.ai aggregates every recruiting study in Grand Rapids from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Grand Rapids?
There are approximately 413 recruiting clinical trials in Grand Rapids, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Grand Rapids pay participants?
Most recruiting trials in Grand Rapids compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Grand Rapids?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Grand Rapids?
The most common conditions under active study in Grand Rapids include Colorectal Cancer (15), Advanced Solid Tumors (13), Advanced Solid Tumor (11), Breast Cancer (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Grand Rapids?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Grand Rapids on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Grand Rapids?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Grand Rapids?
Recruiting research sites in Grand Rapids include Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Trinity Health Grand Rapids Hospital, START Midwest, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Grand Rapids right now?
The largest active categories in Grand Rapids are Cancer & tumors (222), Cardiovascular (20), Neurology & pain (11). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.